Burkitt Lymphoma Research Paper

My sister has lived in Baltimore most of her life, for undergraduate studies, pharmacy school and now working as a pharmacist. Although she attended Notre Dame of Maryland University, she often heard different stories about Johns Hopkins experimenting on people. I heard that they would find vagabonds or street people to experiment on as well as the patients in their hospital, or people in different countries. Johns Hopkins is a well-known and respected, but now also feared. With this in mind I, understand the Lacks family’s fear of Hopkins and what was done to their mother. Back in February, my best friend since childhood, Abdul Conteh, was diagnosed with an aggressive, stage four cancer called Burkitt Lymphoma. He skyped me and personally told me about his diagnosis, after hearing that, my life changed instantly. To think about how her children must have felt to lose their mother, especially around those ages was

The symptoms of Burkitt's depends on the type that the person has acquired. Endemic, which is the African form usually starts as tumors of the facial bones, commonly the jaw, it may affect the gastrointestinal tract, ovaries, and can spread to the Central Nervous System. It can cause nerve damage, paralysis, and weakness. Immunodeficiency and Sporadic, the type that is more often seen in other areas of the world but is more frequently seen in the Untied States. This type usually starts in the bowels and forms a mass in the abdomen, because of this bone marrow, the liver, and spleen are usually involved. These two forms can also start in the ovaries, testis, or other organs and will eventually spread to the brain and spinal cord fluid. Symptoms that are involved with all three variants consist of bowel problems, fatigue, loss of appetite, nausea, night sweats, unexplained fever, and weight loss.

Castleman 's disease is a rare condition characterized by benign, non-cancerous, growths that develop in the lymph node tissue throughout the body. With the exception of the central nervous system (CNS), lymph nodes may be found in every area of the body. Most often, these growths occur in the chest, stomach, and/or neck, but may also be found in the armpit, pelvis, and pancreas. Usually the tumors represent abnormal enlargement of the lymph nodes normally found in these areas (About Castleman Disease). The abnormal overgrowth of cells of the lymph system is similar in many ways to lymphomas, which is cancer of lymph nodes (Weerakkody, Y).

1. Sweating, high temperature, weight loss, fatigue, anemia, and itching all over the body are symptoms of Lymphoma.

Today I will be talking about three aspects of Leukemia; First what it is and one of the possible causes, Secondly what are the recognizable symptoms and what tests doctors use to identify leukemia in a young child. And what

Cancers arising from the lymph nodes or other sites of lymphoid tissue are broadly termed lymphomas. This group of diseases is divided into Hodgkin’s disease and non-Hodgkin’s lymphoma. In both conditions, there is a replacement of normal lymphatic tissue by collections of abnormal lymphoma cells.

Since Wilms tumor is a rare kidney cancer, diagnostic tests are usually not performed on children that do not show any signs and symptoms like abdominal swelling. However, kids under 8 years old that have any of the genetic factors or birth defects must undergo regular examination where physicians do various tests that will determine if any tumor is there in order to detect it early and prevent spreading. The main focus in there tests are the abdominal area of the child as well the presence of elevated blood pressure. First of all, some blood tests are done to check the overall's child health. A urine test is performed in order to check the kidney function. Subsequently, imaging tests are performed. They will help in detecting the tumor, along

EBV is associated with malignant tumors, in particular: Burkitt’s lymphoma, which is especially prevalent in immunocompromised individuals. EBV has the ability to immortalize B-lymphocytes by hindering apoptosis signals within the cell. The virally encoded cells, therefore, proliferate to high numbers in the body leading to malignancies. EBV can then change the B-lymphocytes to lymphoblastoid cell lines. Individuals who carry the virus in most cases do not go on to have Burkitt’s Lymphoma because the immune system can recognize the transformed cells and destroy them before they cause malignancies. The immune system in immunocompromised patients, however, is not typically able to destroy these cells, making the individual at risk for malignancies

My patient is a 64-year-old that came in for upper abdominal pain. She felt her pain was worse when she lied down flat, so she had been trying to sit up and lean forward for most of the day. As the day went on her pain got worse, so she came into Emergency Department for further evaluation. She did not have any nausea or emesis and no change in her bowel habits. No fevers or chills. No trauma to the abdomen. In the hospital, she is diagnosed with acute pancreatitis.

Burkitt’s lymphoma is a very aggressive form of B-cell non-Hodgkin lymphoma. The disease is related with Epstein-Barr virus and was one of the first tumours shown to have a chromosomal translocation. The Burkitt’s lymphoma disease is the most common childhood cancer where malaria is predominantly an epidemic. About10% of all malignant diseases in children under 15 years of age. Disease is very common in those whose immune system is not functionally efficient. With the help of intensive chemotherapy, children are in better health. On the other hand, children in third world countries are not as aggressive in treatment of Burkitt’s lymphoma. The right prognosis helps doctors evaluate the initial steps of Burkitt’s lymphoma.

Pancritits is an inflammation of the pancreas characterized by a process in which the digestive enzymes are spilled out to autodiagest the pancreatic paranchema(1). Pancreatits is known to be found in two major forms, one of which is marked by the presence of inflammatory cells resulting in reversible structural and functional changes; known as acute pancreatitis (AP). On the other hand, chronic pancreatits is known to have irreversible changes that ultimately results in fibrosis and loss of exocrine and/or endocrine function(2). We focus here on acute pancreatitis in children.

Pancreatitis is the inflammation of the pancreas. It’s located in the stomach and its function is to provide the body with hormones to aid in the digestion, regulating glucose. The triggers for this health condition can be linked to heredity, lifestyle choices and injuries to the abdomen.

When a parent takes their child to the doctor the last thing they want to hear is that their child has cancer. Unfortunately, it is not uncommon for a child to be diagnosed with Acute Lymphoblastic Leukemia, also known as ALL. Acute Lymphoblastic Leukemia is one of the most common forms of childhood cancer, and “makes up approximately 25% of cancer diagnoses among children under 15 years old” (3). Children under five years of age are at the most risk of developing ALL. Since it is an acute form of cancer once the onset has begun the disease quickly begins to worsen, therefore patients must seek treatment as soon as possible. “ALL is different than other diseases in that it is not just a single disease but also rather a group of related diseases with different subtypes”(1). This uniqueness causes the treatment of ALL to depend on the subtypes the patient has, therefore each

Lymphoma is unifying name a blood cancer that develops in the lymphatic system. There are two types, Hodgkin Lymphoma and non-Hodgkin Lymphoma. Both are cancers that affect the body’s defense system. After being diagnosed, approximately seven to ten years are left before death, however, many are able to survive longer than the given amount. Survival rates have doubled to 87.7 percent in the white population since 1960-1963, which has become one of the curable cancers, with a 71.4 percent increase for non-Hodgkin for all people. Signs of lymphoma can be seen from the size of large cells with two or more nuclei, or can be from infiltration of B cells or T cells, both that aid our lymphatic system. Symptoms can be Asymptomatic or the same as Leukemia.

Wilms tumor is a cancer that starts in one, or rarely, both kidneys. It is most often found in children about three years old, and is uncommon in children older than six. It can show up as a swelling or lump in the belly. This type of cancer accounts for about 5% of childhood cancers (American Cancer Society, 2010).