Big Idea 1 (Unit 1)
Chronic Obstructive Pulmonary Disease (COPD) is a long term respiratory disease. It is characterised by a slowly progressive irreversible airflow obstruction that is due to a loss of lung elasticity resulting from parenchymal destruction and peripheral airflow obstruction. It is estimated that 80 % to 90 % of all cases of COPD are caused by cigarette, but it can also be caused by genetic disorders. Identification of genetic markers that predict the rate of loss of lung function may help in disease prevention and improved management in the future (1).
Why
Approximately 1.5 million Canadians suffer from chronic obstructive pulmonary disease, and an estimated 1.6 million remain undiagnosed. In the United States, COPS is the third leading cause of death (2). It is a disease of increasing public health importance around the world. It is one of the commonest causes of death and the only common cause of death which is increasing (3).
How
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Cigarette smoking is currently a causal factor in more than 90% of patients in westernised societies, so environmental factors are clearly very important in the disease (4). However, in Caucasians only 10–20% of chronic heavy cigarette smokers develop symptomatic COPD, suggesting that genetic factors are likely to be important in determining which cigarette smokers are at risk from developing airflow obstruction. Furthermore, some patients develop airflow obstruction at an earlier age, again suggesting that genetic factors may determine the progression of
R.W. appears with progressive difficulty getting his breath while doing simple tasks, and also having difficulty doing any manual work, complains of a cough, fatigue, and weight loss, and has been treated for three respiratory infections a year for the past 3 years. On physical examination, CNP notice clubbing of his fingers, use accessory muscles for respiration, wheezing in the lungs, and hyperresonance on percussion of the lungs, and also pulmonary function studies show an FEV1 of 58%. These all symptoms and history represented here most strongly indicate the probability of chronic obstructive pulmonary disease (COPD). COPD is a respiratory disease categorized by chronic airway inflammation, a decrease in lung function over time, and gradual damage in quality of life (Booker, 2014).
COPD is one of the greatest causes of disability and mortality in the twenty first century with future predictions painting an even graver story. Occupation, genome, and primarily smoking are the main causes of COPD. COPD is the third leading cause of death in America, claiming the lives of 134,676 Americans in 2010. Symptoms are typical of a constant smokers cough which progresses into the debilitating palliative stage of the disease; the development of co-morbidities exacerbates these symptoms. COPD has a complex pathophysiology involving hyperinflation, excessive mucus production and airway remodeling; diagnosis is through lung function tests. COPD is poorly managed with few effective treatments and a poor
COPD is almost always caused by smoking, or second hand smoke. The tobacco smoke irritates the airways and destroys the fibers in the lungs. Breathing in chemical fumes, dust, or air pollution over a long period of time may also cause it. It usually takes a long time for the lung damage to start causing symptoms, so COPD is most come in people who are older than 60.
Chronic obstructive pulmonary disease, commonly known as COPD, is a slowly progressive inflammatory respiratory disease that affects the airways in the lungs. This makes it difficult for affected individuals to breath and get enough oxygen into their body. According to health statistics, COPD is the third leading cause of death and disability in the U.S.
The cause of COPD is from long term smokers and also from people who smoke marijuana which increases a higher risk of COPD. Normally it begins with a cold or infection of the pharynx. Chest pain along with coughing having shortness of breath, and wheezing
First step preventing COPD is to know how it affects the body and the path taken; this is called the pathology. In normal, healthy breathing a person breathes in air that is moves through the bronchial tubes to the bronchioles. At the end of the bronchioles there are air sacs called alveoli. The alveoli are elastic air sacs that control the gas exchange of oxygen and carbon dioxide to the body (Smoking, 2016). The alveoli consist of elastic tissue so when a person breaths in the the alveoli can expand and when the carbon dioxide is released it can deflate and return to it’s normal size.
The study included 100 patients with COPD. All patients fulfilled the inclusion and exclusion criteria. According to its demographic and clinical parameters and treatment groups differ among themselves. Completed the study, all patients included in the study. The therapy in all patients with a clinically meaningful improvement of symptoms was observed.
The most common cause of COPD is smoking, since inhaling tobacco smoke for a long time destroys the lung tissues and irritates the airways. However, second-hand smokers seem to be in danger, as well.
The topic is Chronic Obstructive Pulmonary Disease (COPD). It is an umbrella term used for respiratory disorders such as chronic asthma, chronic bronchitis and emphysema. It is a serious condition that restricts airflow to the lungs and is not fully reversible. It is a major cause of morbidity and mortality in Australia. More than 1 in 20 Australians over 55 have COPD and is also the fifth leading cause of death. There is also a rate of 1,008 per 100,000 of the population aged 55 and over being hospitalized for the condition. The rates among Aboriginal and Torres Strait Islanders compared with non-indigenous Australians are 2.5 times as high (Australian Institute of Health and Welfare, 2016). There is no cure however; the management can slow the disease progression and is therefore crucial to the quality of life of patients.
In the vast majority of cases, lung damage leading to COPD is caused by long-term cigarette smoking. There are other factors that play into the development of COPD, such as a genetic susceptibility to the disease, because only about 25 percent of smokers develop COPD. In addition, about 1 percent of people with COPD get the disease from a genetic disorder that causes low levels of a protein. This protein is called alpha-1-antitrypsin. This protein is made in the liver and is secreted into the bloodstream to help protect your lungs.
Smoking cigarettes is the leading cause of COPD. Most patients diagnosed with COPD are smokers or have smoked in the past. Prolonged exposure to substances that cause lung inflammation or other exasperations, such as air pollution, chemical fumes or dust, can also contribute to a diagnosis of Chronic Obstructive Pulmonary Disease.
There are many factors that contribute to the diagnosis of COPD. Smoking is the most common cause behind the disease. According to Healthline Networks,
A. has a history of smoking for 50 years and being diagnosed with COPD 2 years ago. Development of COPD and its exacerbations may be a leading caused by bacteria, viruses, or environmental pollutants, including cigarette smoke. Coussa, et al, “Expiratory flow limitation (EFL), as a consequence of airway inflammation is the pathophysiological hallmark of COPD.” Exacerbations fundamentally reflect acute worsening of EFL and there is evidence for both increased airway inflammatory activity and worsening airway obstruction as likely explanations.
I will analyse the prevalence of the condition and what the potential causes may be. My interests have been directed to pre hospital care and community lead treatment packages, which are potentially available to the patient, as this is the acute environment, which I will have contact with in my employment as a paramedic. The initial reading was to understand COPD as a chronic condition, what is COPD? and its prevalence in the population. The (World health organisation, 2000), states that one in four deaths in the world are caused by COPD. In 2010 (Vos T Flaxman etal, 2012), says globally there were approximately 329 million, which is 4.8% of the population who are affected by this chronic condition, In the UK (NICE, 2010), have estimated that 3 million people suffer from COPD, with more yet to be diagnosed. This information about the amount of people living with this condition was surprising, as I little knowledge of its existence. During the early 1960’s (Timothy Q. Howes, 2005), says the term COPD had been designated as a single term unifying all the chronic respiratory diseases. Since then the term COPD, has been sub divided in to three umbrella areas, Bronchitis, Emphysema and Chronic asthma, which are separate conditions, which I have been previously aware of as their individual conditions. The 58 year old patient who we visited,
The main characterizing feature of Chronic obstructive pulmonary disease is that there is limitation of airflow because the smoke of cigarette directly damages the epithelial cells of the