Cancer Transfer Factors

Catharina Svanborg says she does; it is human breast milk, and it is killing cancer cells! It has been extremely difficult to convince her science colleagues that the work she is doing is for real! Her lab is not large, and she does not qualify as a high-profile, "big scientist." Besides, her specialty is not even cancer at all but infectious disease. David Solomon, a cancer researcher at the National Cancer Institute (NCI) says that novel ideas in science always challenge the current paradigm. Furthermore, he said, "If this work had come from a well-known lab at the NCI, you'd have reporters calling six days to Sunday. You'd have scientists eager to collaborate. But it's coming from a small lab in a foreign country. It's like General

The immune system of a 3-week old infant is immature with limited antibody production. “A system of active transport facilitates the passage of maternal antibodies into the fetal circulation to protect the child against infectious agents in utero and during the first few postnatal months”(McCance & Huether, 2014, p. 257). It is divided into two systems:

may help kill certain cancer cells and reduce the size of others. Evidence from one cell culture study

Cancer or the big C as it is commonly referred to by laymen is a scary word for people to hear or discuss. The exact cause of cancer is unknown, but is believed to be caused by many elements, including diet, chemicals, tobacco, radiation, and mutations that occur in the human body, as well as defective cells and genes. Experts know that cancer requires oxygen and nutrients to grow more cancer cells. The paper will explore the concept of angiogenesis, what it is, and how it impacts cancer, along with exploring activators and inhibitors to stop the growth of cancer. Natural products will be reviewed to highlight any potential value in eliminating and reducing the risks of getting any type of cancer.

In “The Mysteries of Milk,” Natalie Shenker, PhD and co-founder of the Hearts Milk Bank, emphasizes the importance of breast milk, writing “it is critically important to prevent infections and necrotising enterocolitis (NEC), a catastrophic gut condition that carries a mortality rate of 40%” (Shenker, 2017, p.11). Breast milk, especially colostrum, which is produced two to three days after birth, provides not only an energy-rich source of food for an infant but is composed predominantly of white blood cells which can “engulf and absorb harmful microorganisms” (Shenker, 2017, p.12). The cells are breast-specific macrophages that produce lactoferrin, an iron-binding protein that helps the infant absorb and store protein, and lysozyme, an

“The Breast are considered to be in the reproductive system because they are able to produce milk during childbirth” ("Breast Pictures, Anatomy & Anatomy | Body Maps," 2005). There are many risk factors that increase a woman’s chances of developing breast cancer, but it is not yet known exactly how some of these risk factors cause cells to become cancerous. Some of the few risk factors that are included are taking

An exclusively breastfeeding mother’s mammary glands produce a total of approximately 750 mL of milk per day. Synthesized from substances in the mother’s blood, breast milk contains all necessary nutrients for a baby’s healthy development. For example, human breast milk consists of a specific combination of proteins, fats, carbohydrates, and vitamins. Additional milk components include minerals, electrolytes, and water. The nutrient concentrations fluctuate as lactogenesis progresses. Changes in milk composition and volume are controlled by multiple hormones, including cortisol, insulin, and prolactin. Along with composition, the volume of produced milk changes throughout lactogenesis. The

Breast cancer is the most common cause of cancer-related death among females in the world. It is known for “have both a genetic and non-genetic etiology” (Milne et al., 2010). It involves a combination of several factors- such as “genetic, environmental and behavioral risk factors”- that are unique to each individual (Nickels et al., 2013). This type of cancer is represented by a malignant tumor manifested in breast cells such as the line duct and line lobules cells, just to name a few. Because there are different types of breast cancer, it is harder to create an effective treatment or therapy that would lower or prevent its death rates. Despite advances in technology but lack of monetary support, there is a higher prevalence in African countries (U.S. breast cancer statistics, 2013). It has been found that “two thirds of breast tumors express estrogen receptors” (Lopez-Tarruella & Schiff, 2007). Because of this, growth factor receptor signaling and hormone therapies have been shown as promising treatments to prevent and/or to find a cure for this cancer.

The most important reason breast milk is better for an infant’s immune system is because it is loaded with

The data showed in figure 6, are form Boyden chamber assay that was used to observe the invasion or movement of cells from one place to another. In this assay the authors used three treatment groups; i. 1mM melatonin supplemented with 10% FBS (Fetal Bovine Serum), ii. 10% FBS supplement defined as positive control, and iii. 0.5% FBS supplement as a negative control. Although the figure was shown in two sub-part, but we can compare the melatonin group with the negative control group because all data were normalized by positive control. The authors conducted the Boyden chamber assay in canine (CMT-U229) and human (MCF-7) breast cancer stem cells. 1mM melatonin decreased cell invasion by 40.4% in canine breast cancer stem cells and by 56.3% in human breast cancer stem cells compared to the positive control. However, negative control further decreased cell invasion compared to melatonin treatment. Although the authors did not mention any exact number, it could be assumed from figure 6 that negative control decreased cell invasion by about 90% in canine breast cancer stem cells and by about 95% in human breast cancer stem cells compared to positive control. Therefore, the percentage of inhibition of cell invasion was higher for negative control compared to the melatonin group in both types of cancer stem cells. However, we cannot confirm that this comparison is precise due to lack of statistical comparison. Student’s t-test was used to compare between two groups, whereas, ANOVA needs to be used for three or more groups. Therefore, if we want to compare among positive control, melatonin treatment and negative control we need to run one-way ANOVA

DMBA is an effective chemical used to induce breast tumorigenesis in rats. In this study, DMBA treatment led to the development of tumors by rats as revealed by tumorigenesis analyses and the histopathological examination. Treatment with lycopene reversed the pathological changes showing the efficiency of lycopene in breast tumor treatment. This result was in accordance with previous studies where lycopene alone or in combination with other products was proven to have anti-tumor activity.

Group I served as normal control animal. Group II animals received DMBA (60 mg/Kg) i.p. to generate mammary tumor. Animals in Group III were breast cancer rats treated with xxxxx mg lycopene/kg body weight (bw) daily once for 4 weeks after 90 days of DMBA induction. Group IV were breast cancer animals treated with xxxxx mg lycopene/kg body weight (bw) daily once from the onset of DMBA induction. Group V were control animals treated with lycopene as mentioned above. Palpation for mammary tumors was performed weekly for each DMBA-treated rat. When the first tangible mammary tumors (∼ 0.5 mm in diameter) were noticed, the tumor length (L) and width (W) were determined once weekly. The tumor volume was computed using the formula (L ×W2)/2. Rats were sacrificed when they became moribund. The amount of mammary tumors grown in each rat was calculated and

A lot of these problems seen in formula feed babies are due to the fact that the particular composition of the formula doesn’t suit their digestive system. Breast milk consists of the optimum proportions of fats, carbohydrates, proteins, vitamins, minerals and water. It is extremely digestible for a new-born baby because the milk is naturally refined to perfectly suit the baby’s digestive system. The milk also contains growth factors such as, epidermal growth factor (EGR) and insulin-like growth factor. The epidermal growth factor works by helping to prepare the lining of the gut to absorb the nutrients from the milk consumed. Insulin-like growth factor is believed to be one of the primary factors regulating early growth and development. Breast milk also contains essential fatty acids that are not present in most formula milk products. The two essential fatty acids present in breast milk are docosahexaenoic acid and arachidonis acid. Both of these play a vital role in optimal development of the central nervous system, intellectual and visual development in babies. Furthermore, one of the most prominent advantages associated with breast feeding over formula feeding babies is that, breast milk naturally changes composition to correspond to the stage of development of the infant. For example, colostrum is the name given to the first milk produced post-delivery. It has an abundance of white cells and antibodies, it also contains a

Each person knows about Breast cancer these days, due to the fact that humankind witnesses countless organizations working for this sole purpose diligently every day. Periodically we meet or hear individuals struggling with this devastating category of cancer, which is particularly prevalent in women. According to the recent facts and figures from American Cancer Society about the number of deaths from breast cancer in US in 2013, among all ages, has gone up to 39,620[1]. This portrays a massive number, nevertheless analyzing the mortality trend from 1990-2010, one can grasp the death rate has been decreased to 34% [1]. Consequently, the known reason behind this decline is attributable to the improvements in our health care system in terms of treatment, in conjunction with the early detection of breast cancer. Discussing about the risks of having breast cancer, we all know that there are certain factors which can’t be modified that comprise sex, family history, age, early menarche, and late menopause; however, there are several factors which can be taken care of for instance abstinence from smoking and alcohol consumption, use of combination oral contraceptives, avoiding obesity, and increase the usage of vegetables and fruits in your diet could prevent a significant proportion of the population from getting this cancer [1]. Nevertheless, when populaces mention the dietary changes that can give an

Transition to 1st main point: First, let’s talk about the anticancer properties that are found in certain teas. ll. Body