Candida Essay

Decent Essays
By far the most common causes of invasive fungal infections are members of the genus Candida. Candida is a dimorphic fungus and it the highest investigated and most common fungal pathogen in humans, capable of evading the human complement system. Yeast may lives within the intestinal environment of the human body and usually causes no major health issues. But due to various environmental factors Candida can change into an invasive multicellular form from a unicellular or yeast form and begins to reproduce very rapidly. As it spreads it builds a biofilm that can range from thickness and begins to multiply within 24 hours of colonization as a means of protection. As Candida becomes multicellular the biofilm which is composed of cellulose are bounded together by lignans with stickiness properties. The biofilm also contains fibrinogen and fibronectin which are the same materials that the body uses to coagulate the blood at wound sites. The form it takes depends on environmental changes and this flexibility makes it highly adaptable. Switching to the hyphae phase which is the long branching filamentous structure of the fungi is based primarily on temperature and pH changes.…show more content…
The change is spontaneous and reversible, though possibly controlled by regulatory gene expression. One structure of invasive candida grows as a smooth round white colony, and one grows as a rod-shaped in flat, gray colony. This can be the same species of candida and it can switch between the phases as a method of adaptation. Another strain of candida known to undergo switching or as I like to say, shape shifting, produces seven different types of colonies. This switching ability is reversible and is inherited from one generation to the other. Research has also shown that structural chromosome rearrangements are a way to maintain genetic diversity and is an adaptation strategy of this
Get Access