Cannabinoid Analysis

McGrath, J., Welham, J., Scott, J., Varghese, D., Degenhardt, L., & Hayatbakhsh, M. et al. (2010). Association Between Cannabis Use and Psychosis-Related Outcomes Using Sibling Pair Analysis in a Cohort of Young Adults. Arch Gen Psychiatry, 67 (5), 440. http://dx.doi.org/10.1001/archgenpsychiatry.2010.6

David Casarett a Physician in California explains how he learned about Medical Marijuana and how he has come to recommend other physicians to research and consider medical marijuana. Casarett asks, “What if mainstream health care operated more like a medical marijuana dispensary?”

Studies have determined that two of the major cannabinoids found in cannabis, tetrahydrocannabinol (THC) and cannabidiol (CBD)

With the understanding of the pharmacokinetic and pharmacodynamic actions of cannabinoids, coupled with benefits that many have received from cannabis, the emergence of a paradoxical cannabinoid-related condition called Cannabinoid Hyperemesis Syndrome (CHS) is perplexing. CHS is a relatively newer condition appearing in emergency rooms across the country, with the first documented case in 2004 in Australia. Patients with CHS present to the emergency room with intractable vomiting, intense recurrent nausea and abdominal pains and a history of chronic cannabis use. The cycles of vomiting begin with intense nausea in the morning with intractable vomiting lasting for hours. The episodes occur every couple of weeks, or sometimes months, some lasting

The marijuana screening inventory is an individually administered test. It was developed as a psychometrically reliable and valid tool for clinical use in general health and primary care settings. This is a thirty-one question assessment that assess the participant need for marijuana. The assessment is completed with paper and pen and takes approximately ten minutes to complete. Participants have the ability of answering yes or no to each question. After the participant has completed the assessment the scores are added calculating yes as one point and no for zero points. Seven or more “Yes” responses suggest a “High Risk-Problematic” pattern of marijuana use; four to six “Yes” responses suggest a “Moderate Risk” pattern; one to three a “Low

These summary debates summarize and discuss are the calculation of cannabis use for many individuals with PTSD. According to the article, Does Cannabis Cause Exacerbated or Ameliorate Psychiatric Disorders, Neuropsychopharmacology (2016) 41, the authors of the article gives opposing viewpoints concerning the influence cannabis use has on those with post-traumatic stress disorder, the relationship with schizophrenia, and psychotic disorders.

The overall goal of my research is to better understand the roles that fatty acid binding proteins (FABPs), specifically epidermal-FABP (FAPB5) and brain-FABP (FABP7), play within regulating the endocannabinoid system and to understand the role of FABP in addiction. The endocannabinoid system is linked with the rewarding effects of abused drugs. Central to the endocannabinoid system is the cannabinoid type 1 receptor (CB1R), which is expressed ubiquitously throughout the brain. Within the brain reward circuit, activation of CB1Rs regulates the strength and plasticity of glutamate and GABA synapses. Specifically, dopaminergic projections from the ventral tegmental area (VTA) to the nucleus accumbens (NAc) plays a critical role in reward

During the featured article “how to make your exercise high last,” the author, S. Angle, describes the high you receive during and after a workout. This high is a feeling that you can’t miss, it happens after a great workout is finished, this feeling puts one's self in an astounding mood, plus making you ready for your next workout. The only problem with this is that it simply lasts for about 20 to 30 minutes before the feeling begins to go away. Studies by Johannes Fuss, Ph.D., the lead research of this study, have recently proven that this high feeling that many people enjoy are from our levels of endocannabinoids, and endorphins being at high levels. Endocannabinoids tend to have a more powerful effect on how we feel. Firstly, Endocannabinoids

It was found that patients gained weight and a heightened sense of appetite. The change in mass and increase in appetite is due to marijuana or the oral alternative identified as Delta-9-tetrahydrocannabinol (THC) which is inside dronabinol (Lutge, Gray, & Siegfried, 2013). THC had immense effects on the nausea, appetite, and other uncomfortable phases allowing many patients to be relieved of their discomfort. THC is inside the dronabinol which is man-made form of cannabis. Dronabinol can either be smoked or ingested by the subjects. This synthetic drug is commonly used in the place of a plant form of cannabis. Collectively dronabinol and THC causes the patients to be twice as likely to gain two kilograms or more in body weight (Lutge, Gray,

Cannabis is one of several midly intoxicating hallucinogenic drugs that is prepared from various parts of the hemp plant and has the effects of oth stimulants and depressants on different parts of the nervous system. This drug, cannabis could be called many things such as: weed, pot, grass, dope, hash, herb, chronic, or reeper. The effects cannabis could have on a person or driver is the poor ability to concentrate which would be bad for a driver and could cause them not to notice things going on around them. The light headiness a driver could get while taking cannabis is a safety hazard to the driver and others around the driver. Cannabis could cause colors to a persons eyes or dilate their pupils which would make a driver lose focus of the

The topic of this article is the effects of adolescence female cannabinoid exposure on male offspring’s response to opiates. The particular study is important because marijuana is one of the most abused drugs among females. Since women have babies it is important to understand any potential health risk of the cannabinoid exposure on their offspring. Previous studies have shown increased risks of anxiety and depression, as well as decreased motivation and reading comprehension skills (Brynes, 2012, p 1348). The current study looks at whether exposure during adolescence will affect future offspring. Therefore one does not want to alter fetal development, even if the mother is not using during pregnancy. The purpose of the current study was

Marijuana’s active ingredient is tetrahydrocannabinol (THC) it contains a chemical compound called cannabinoids which are naturally found in the human anatomy. THC affects the central nervous system by binding to cannabinoid receptors that are present in the brain which triggers a euphoric response. The active ingredient in marijuana is quickly absorbed by the blood and has an immediate effect on the brain and other drugs. The drug comes from the hemp plant Cannabis sativa and it’s the seeds and leaves that are used and also the flowers are usually dried. (Above the Influence, 2015)

The overall focus of my research is to better understand the roles of fatty acid binding proteins (FABPs), specifically epidermal-FABP (FAPB5) and brain-FABP (FABP7) and their influence on addictive behavior. Central to the endocannabinoid system is the cannabinoid type 1 receptor (CB1R), which is expressed ubiquitously throughout the brain [1]. Within the mesolimbic system, activation of CB1Rs modulate the release of dopamine. This is done by CB1’s ability to inhibit GABA and glutamate projections onto ventral tegmental area (VTA) dopamine neurons [3]. CB1R agonists have been shown to increase dopamine levels in NAc, thereby increasing the reinforcing effects of drugs of abuse [4]. In contrast, blockade of CB1Rs can decrease the rewarding

The cannabinoid receptors are present throughout the body. Researchers have identified two cannabinoid receptors the cannabinoid receptor type 1 or the CB1 receptors and the cannabinoid receptor type 2 or CB2 receptors. The CB1 receptors are mainly found in the brain and the nervous system. Furthermore, CB1 is the main receptor for the photocannabinoid THC and its twin, anandamide which is one of the body’s naturally occurring cannabinoid which THC mimics or mirrors. On the other hand, CB2 receptors are found mainly in the immune system and its associated structures (Kossen, n.d.).

While there have been countless reports linking sleep deprivation to obesity, how inadequate sleep can fuel weight gain is unclear. According to a new study published in Sleep, the real culprit is the endocannabinoid (eCB) system.