Capillary Essay

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“ According to (P.Charalampos K.Menelaos J Clin Med Res 2011) – Increased capillary is the hallmark of ARDS. Damage of the capillary endothelium and alveolar epithelium in correlation to impaired fluid remove from the alveolar space result in accumulation of protein-rich fluid inside the alveoli, thereby producing diffuse alveolar damage, with release of pro-inflammatory cytokines, such as Tumour Necrosis Factor (TNF)”. So as we can see those fluids that accumulates in the alveoli will tend to leak into the lungs where its difficult for breathing and leads to decreased in oxygen level in the blood or a condition which is known as hypoxemia. This fluid makes the lungs capacity and also its shape or becomes rigid where it will be difficult to inflate.…show more content…
In order to improve the amount of oxygen and to reduce the burden to the lungs, most ARDS patients will be monitored on a ventilator to support them for breathing, while the lungs goes through process of healing. If the inflammation and fluids still persist in the lungs some patients may develop into scarring of the lung tissue, which is known as fibrotic stages of ARDS. During this stage the lungs will be able to inflate and deflate and all of sudden it may stop, which may cause the lungs to collapse and also a condition known as pneumothorax. Neutrophils are enlisted to the lungs by cytokines, become activated and releases toxic mediators, such as reactive oxygen species and proteases. Extensive free radical productions defeats endogenous anti-oxidant and will cause oxidative cell damages. And “according to C.Melissa Pharm D, C. Michelle, Pharm D, R. Mark, MD in Drug Update journal pathophysiology of ARDS is characterized by 3 progressive clinical stages, the exudative, proliferative, and fibrotic
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