Case Study: Hibiscus Gellan Gum

Aspirin, Caffeine and Salicylamide were extracted from an over-the-counter pain reliever (BC Powder). These components were separated by manipulating their solubilities by adjusting the acidity and basicity of the solution. By doing this, the three components were forced into conjugate acid (or base) forms, causing selective solubility in either an aqueous or organic solvent. These layers were then separated by use of a separation funnel. Once separated, the components extracted were characterized by measuring the melting point and performing a TLC analysis. Also, the recovered aspirin from the first part of the experiment was recrystallized and compared to that of the

Separation and Purification of the Components of an Analgesic Tablet. Cora Bruno, Lab Section E. Aspirin, Caffeine and Acetaminophen were separated from four analgesic tablets of Excedrin using extraction techniques. 5% wt/vol NaHCO3, 4M HCL, ethyl acetate and deionized water were used to separate the three active components. MgSO4 was used to dry each extraction. Aspirin was isolated using a hot water bath and weighed to determine the percent theoretical recovery and the actual percent recovery of aspirin. After separation, Aspirin (ASA), Caffeine (CAF), and Acetaminophen (ACE) were purified and identified using Thin Layer Chromatography (TLC). Standards and purified ASA, CAF, and ACE were spotted on the silica gel (stationary phase) of the

Capsule is the most versatile of all dosage forms. Capsules are solid dosage forms in which one or more medicinal and inert ingredients are enclosed in a small shell or container usually made of gelatin. There are two types of capsules, “hard” and “soft”. The hard capsule is also called “two piece” as it consists of two pieces in the form of small cylinders closed at one end, the shorter piece is called the “cap” which fits over the open end of the longer piece, called the “body”. The soft gelatin capsule is also called as “one piece”. Capsules are available in many sizes to provide dosing flexibility. Unpleasant drug tastes and odors can be masked by the tasteless gelatin shell. The administration of liquid and solid drugs enclosed in hard

In this experiment, aspirin was synthesized from acetic anhydride and salicylic acid made in order to characterize its properties and determine its purity. The purity of the aspirin was examined by its melting point, thin layer chromatography, and UV spectroscopy.

We tested three different brands of bubble gum. The three brands are Bubble Yum, Bazooka, and Bubblicious. There were 3 people that blew bubbles for our experiment. My Mom, Dad, and myself were the three bubble blowers. We each read a couple of articles on the best way to blow big bubbles. We then chewed each piece of gum for three minutes before blowing the bubble. We used a ruler to measure the diameter of the bubble in centimeters. Through my research, I believe that the bubble gum with the highest sugar content will blow the biggest bubble.

Hopewell, GA. This was an agreement set forth by the State of Georgia, that established

The hypothesis was formed under the thought that the fastest dissolving pill would be the most effective because the sooner the ingredients and materials were realized, the sooner they would be able to attack and neutralize the pain, therefore getting the job done quicker or more efficiently. The hypothesis was not supported because, overall, the first two pills to dissolve were both children’s pain killers and were “junior strength”. Therefore, these medicines could not have been the most effective because the strength is significantly weakened to accommodate to young kids, and would not be as effective as normal strength medicines. In order to accurately determine the time taken for the pills to dissolve inside the body, it is very important to create a solution similar to stomach acid. Stomach acid was simulated by heating vinegar, which has the same ph level of stomach acid and shares other similarities in makeup and properties. The vinegar was heated to 36.7 degrees Celsius and constantly stirred to represent the temperature and motion of stomach acid. Eight different pills were timed to see how fast they dissolved. Each type of pill was tested three times in order to find an average for each medicine. The pills tested were Advil, Children’s Advil Grape Flavored, Ibuprofen, Children's Ibuprofen Grape Flavored, Tylenol, Tylenol Liquid Gels, Aleve, and Aleve Liquid Gels. The children's strength pills were the first two medicines to dissolve. Aleve was the slowest to dissolve and took almost two hours to dissolve. The liquid gel capsules were the second and third slowest pills to dissolve. In order, from fastest to slowest to dissolve, the medicines were Children's Ibuprofen Grape Flavored, Children’s Advil

Have you ever taken a bite into a fresh piece of gum and just died?The first chews of gum are the perfect way to start a soon to end experience. The way your tongue dissolve the booming flavor like a baby kicking for the first time ,but it's not the first time...it's maybe the 100th.Or like meeting someone you heard of ,but not met personally .The exciting part is when you're in the middle where the flavor is shy, but acting out at random moments. You chew and chew and chew and chew and chew and chew and with every bite into that clumped of piece of gum filled with saliva and 10 million thriving bacteria. The minty air rushes through your nose relieving your breath of a deadly stench…...and then it ends out of nowhere, but you chew and chew

Have you ever wondered how gelatin gets shape? This research paper is going to talk about additives that make the strongest gelatin. Terms that will be discussed in this paper include gelatin, molecule, collagen, and protein.

Tablets and capsules are two of the most widely use forms of oral medication. Careful and accurate administration of tablets and capsules is critical to providing safe patient care, every effort should be taken to avoid “medication errors” and the dangerous effects they may have on a patient. Some tablets and capsules are formulated with special coatings to manage their discharge and therapeutic effectiveness; crushing, chewing then ingesting them can increase the risk of an adverse reaction. David C. Wordell RPh describes in his article “Should You Crush That Tablet?” “some categories of drugs you shouldn’t alter.” These drugs includes, “sustained release tablets and capsules,” “enteric coated tablets” and “sublingual and buccal tablets.” This literature

The purpose of this investigation is to find out if the coating on pills makes it harder to dissolve.

17 (Scheme 6) was purified by column chromatography (1% MeOH/DCM). The NMR showed that there was still a bit of the starting alcohol present. A second column (1% acetone/DCM) was done to separate the alcohol from the galactoside. The yield was 45%.

Marcela Ramirez-Campos Y et al reported that the effect of formulation variables on verapamil hydrochloride release from hydrated HPMC matrices, among different variables that influence drug release from hydrated hydrophilic matrices, the polymer proportion, the drug dose and the matrix pH can be included. The release profiles showed zero order kinetics for drug dissolution proportions up to 70%.The increase of the matrix pH from 5.0 to 8.0 increased the release rate. The effect of both pH and drug load becomes lesser as the matrix polymer proportion increases from 5% to 15% w/w.

The extraction of the active constituents from the leaves by chewing is very effective with only 9.1% remaining as a residue after chewing. The second adsorptive segment is the stomach and small intestine (Toennes et al.,

Herbal medicines are great alternative for commercially manufactured medicines available in the market. The major reason why herbal medicine differ from modern medicine is because they are produced with 100% natural content. Therefore the plant extract has all the medicinal values that are as effective as modern medicine. Commercially prepared drugs show results quickly but have numerous side effects. However herbal medicines don’t show any side