Case Study : Lincosamides Antibiotics ( Cleocin )

Azithromycin (Zithromax) 500 mg IVPB q24h for~ 2 days then 500 mg PO for~ 7 days

B. After delivery the dose of zidovudine (AZT) will be doubled to prevent further infection.

• the dose to give and how often it may be repeated before referring to the resident’s doctor

For adults and children 12 years of age and older, the recommended dosage is 0.63 mg three times daily, given every 6 to 8 hours (maximum 1.25 mg three times a day).

Make sure you can read the prescription and directions for use. If anything is illegible, ask the prescriber to re-write or type it.

A twenty-five-year old Caucasian female presented to the office with burning with urination. External inspection of the patient’s labia majora revealed genital herpes. Herpes simplex virus infections associated with the genitals are usually deemed type two (Uphold & Graham, 2013). The patient was placed on acyclovir for her outbreak. The current dosage that she is being placed on is 400 mg orally every eight hours for ten days (Medscape, n.d.). There are no medication contraindications for this drug; however, one should not use neomycin orally due to an increase in nephrotoxicity and or otoxicity if the two are taken together (Medscape, n.d.). Other medications such as bacitracin and cidofovir should also not be used with acyclovir due to an increase in nephrotoxicity and or otoxicity if these are

She is without complaints. She has not noted any increase in preterm labor. No signs/symptoms or change in pelvic pressure. She is compliant with bedrest and has help taking care of her son. She is otherwise aware that she should discontinue Motrin next week and is aware of the signs/symptoms that we are monitoring. The placental cord insertion does appear marginal as noted on prior ultrasound and we are following monthly growth. She is aware that after surveillance of cervical length which will the last one we would anticipate would be next week at 32 weeks and after that we would still recommend monthly evaluation of fetal growth. Preterm labor precautions were reviewed. She is scheduled to return in one

Clinafloxacin is a broad-spectrum antibiotic of the quinolone carboxylic acid category that inhibits both DNA gyrase and topoisomerase IV dually in Streptococcus pneumonia. Clinafloxacin, a fluoroquinolone, is currently in development for oral and intravenous therapy of serious infections.

Plan of Care: No laboratory work ordered at this time. Patient prescribed Tobramycin ophthalmic ointment 1/4 to 1/2 inch ribbon to lower conjunctiva every four hours while awake (Medscape, 2014). Patient instructed to keep eye clean using a dilute baby shampoo solution twice daily. The patient is instructed to seek immediate medical intervention for visual changes, fever greater than 100.0, or increasing ocular pain. Return for follow-up appointment in two days (Goolsby & Grubs, 2011). Continue current medication regime as previously prescribed.

Other treatments that could be order are Clarithromycin 500mg twice daily for five days or Clarithromycin XL 1000 mg (Two 500 mg tablets) daily for five days (File, 2017).

Thank you for the opportunity to participate in the care of Ms. Megan Robertson, who as you know is a 20yo female, G2 P0101, currently at 16 weeks 5 days EGA with a pregnancy complicated by a history of prior spontaneous preterm delivery at 35 weeks of gestation and maternal underweight status. She presents today for evaluation of cervical length and fetal growth due to her history of prior preterm delivery and started her course of 17-alpha hydroxyprogesterone caproate injections today and these are weekly injections for her to reduce the risk of preterm birth secondary to her history of prior spontaneous birth.

The benefits of this would be that the delivery of the antibiotic is less invasive. It will also decrease her risk for further infection. This could

If a patient with suspected infection has a negative PCR test and fetal ultrasounds continue to demonstrate no signs of congenital toxoplasmosis, spiramycin therapy should be continued until delivery. If the patient is diagnosed, spiramycin should be discontinued at 18 weeks, and combination therapy should be initiated until delivery. It is strongly recommended that pregnant patients with acute infection consult with experts at either the Palo Alto Medical Foundation Toxoplasma Serology Laboratory or the U.S. National Collaborative Treatment Trial

First option for treatment includes a drug by the name of Metronidazole 500 mg, also referred to as Flagyl or Protostat. The listed medications are all forms of an antibiotic. Treatment consists of one of the following, taking 2g of Metronidazole (4 tabs) as a single oral dose, taking 250 mg of Metronidazole orally 3 times a day for seven days or 500 mg of Metronidazole twice a day for 7 days. Since this is an antibiotic alcohol should be avoided and be acknowledged that antibiotic decrease the effectiveness of birth control. An additional treatment of Trichomoniasis can also be Clotrimazole which is 1 tablet inserted vaginally at bedtime for 7 days. During pregnancy, the suggested treatment changes such as Metronidazole can be taken only after the first trimester to ensure no harm is done to the unborn baby. During this time of treatment, the infected partner should also be treated as well so that the disease does not transfer back and forth between hosts. There is also a 1 in 5 chance of a person become infected again so it is important to visit with your doctor again in symptoms persist or come back after

(Igual-Adell et al., 2004).It has also been registered as the drug of choice in the World Health Organization’s list of essential drugs for the treatment of human strongyloidiasis (Albonico et al., 1999).The dosage generally recommended is of 200 mm/kg of body weight administered orally once daily for 1-2 days (Mejia and Nutman, 2012). Treatment is repeated if necessary 2-3 weeks after the first course to ensure eradication of infection (Segarra-Newnham, 2007). Although this is the standard dose administered for the treatment of the disease but the dosing interval and the length of therapy depends on the stage of diagnosis and the severity of the diseases. Also the prompt treatment is essential for improving the patient outcome. Moreover, combined therapy using ivermectin and thiabendazole or ivermectin and albendazole has been recommended in patients with disseminated disease (Segarra-Newnham, 2007). It is important to note there is an issue with Oral absorption of ivermectin in severe strongyloidiasis patients due to hypoalbuminemia, paralytic ileus and sometimes increased drug clearance (Turner et al., 2005). In such cases, it is administered subcutaneously or rectally. The dose for the subcutaneous ivermectin administration is different from the oral administration of the drug. Prescribed dosage