Case Study 2: Lincosamides Antibiotics
Jenny Rodriguez is a 28 - year – old para 2 gravida 3 woman. She is 28 weeks pregnant and is diagnosed with bacterial vaginosis. With Jenny being a pregnant woman we have to carefully, assess what will be prescribed to her confirming it will not harm the fetus or baby. We used careful consideration and looked at medications to treat vaginosis, reviewed literature and other important information for pregnant woman for vaginosis was discussed. Our group feels that clindamycin would be the best treatment with the least side effects because it has shown no harm to harming the fetus as well. Our group discussed this via e-mail and text and contacted promptly as needed.
1. What is the dosage of Clindamycin (Cleocin) you will prescribe?
A. Clindamycin at the dose of 300 mg by mouth twice daily for seven days would be prescribed. According To Up-To-Date, the oral treatment has not shown any adverse fetal or obstetrical effects.
2. What is the recommended dose according to Up-To-Date?
A. UpToDate (2016), list three possible treatment options. Metronidazole 500 mg orally daily for seven days, Metronidazole 250 mg orally three times daily for seven days, or Clindamycin 300 mg orally twice daily for seven days. In the past Metronidazole was not given to women in their first trimester, but CDC now considers it safe based on meta-analysis studies.
3. What are the pharmacokinetics, pharmacodynamics, and pharmacotherapeutics of the lincosamide