Ulcerative Colitis
Ulcerative Colitis (UC) is a chronic, idiopathic disease of recurring inflammation that affects mostly the colon. Similar to Chron’s disease (Chron’s), Ulcerative Colitis is a type of inflammatory bowel disease that is classified as auto immune. The difference between Chron’s and Ulcerative Colitis is the location of the inflammation. Inflammation occurs when the mucosal barrier is broken down in the intestine. Damage to the mucosal barrier and epithelial cells leads to an increase in gut permeability. With Chron’s inflammation can occur anywhere in the digestive tract, while Ulcerative Colitis is only present in the large intestine also known as the colon. Occurring more often than Chron’s, North America and Northern Europe
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There are many treatment options for patients diagnosed with ulcerative colitis with a similar goal of remission in mind. The main line of prescriptions used to treatment Ulcerative Colitis are corticosteroids, antibiotics, aminosalicylates, and immunomodulators. The aminosalycilates or salicylic acid is the most common treatment and comes in oral form or enema (given rectally) form for a more local approach. Aminosalicylates work as an anti-inflammatory when broken down by the gut flora. During acute episodes’ corticosteroids are used to control inflammation and to help achieve remission. Corticosteroids work by suppressing the immune sytem, so long term use of corticosteroids can suppress the can hinder adrenal sufficiency and cause chemical dependency. Antibiotics are usually ineffective in the treatment of ulcerative colitis but can help with initial symptoms and complications like an infection.. Immunodialators are the newest drug for treatment and are used in patients with long term steroid use, they are effective in suppressing the natural killer cell activity and t-cell function. Though effective, the side effects of this drug class include pancreatitis, diarrhea, and …show more content…
“A study was performed with nicotine patches or gum added with previous medication, 17 out of 35 patients in the nicotine group went into complete remission compared with 11 out of 35 in the placebo group”(Head 259) It is theorized that the nicotine causes increased production of mucus in the mucosal barrier and shrinks blood vessels which lowers inflammation.(Guslandi, 482) Although the side effects are discouraging,( nausea, lightheadedness, and headaches) there is some proof that nicotine helped UC patients into remission along with prescription medication. Unexpectedly heparin was also found to improve symptoms, “patients with UC have a greater risk of developing coagulation problems such as deep vein thrombosis (DVT). In treating patients for DVT with heparin, an improvement in UC was noted.” (Head,
Crohn's disease is an inflammatory bowel disease (IBD). It causes inflammation of the lining of your digestive tract, which can lead to abdominal pain, severe diarrhea and even malnutrition. Inflammation caused by Crohn's disease can involve different areas of the digestive tract in different people. The inflammation caused by Crohn's disease often spreads deep into the layers of affected bowel tissue. Like ulcerative colitis, another common IBD, Crohn's disease can be both painful and debilitating, and sometimes may lead to life-threatening complications. Although it may involve any part of the digestive tract from the mouth to the anus, it most commonly affects the last part of the small intestine (ileum) and/or the large
I really enjoyed reading your response to DQ and how well you discribe Crohn and ulcerative colititis. I also wrote similar discription but I includded the part about family history of having ulcerative colititis and especially from a Jewish descent. Both of these diseases similar symptoms so mecidcal evaluation would have to be done to get the right diagnoses. Crohn disease is also associated with smoking and it is silently increase in women than
An inflammatory bowel disease is characterized by intermittent and recurrent abdominal pain associated with ulceration in bowel function. Inflammatory bowel disease is a group of chronic disorders that cause inflammation or ulceration in the small and large intestines. Most often, inflammatory bowel disease is classified as ulceration colitis or Crohn’s disease but may be referred to as colitis, enteritis, ileitis, or proctitis (Crohn's disease-website).
Crohn 's disease is one of two conditions referred to by the term "Inflammatory Bowel Disease" (IBD). The other condition that is referred to as an IBD is called Ulcerative Colitis. Both Crohn’s and Ulcerative Colitis are conditions that cause recurring or persistent inflammation in one or more sections of the intestine. The literal definition of "inflammation" is "being set on fire". It is a protective reaction that happens when tissue is injured or destroyed. There are two types of inflammations. The first is acute inflammation, which is defined by heat, redness, pain and swelling. The
Crohn’s disease is a life-long condition effecting victims of any age. It is considered a form of an inflammatory bowel disease that causes inflammation in the digestive system. The cause of the disease is unknown. The inflammation is due to the immune system attacking the healthy cells throughout the body’s gastrointestinal tract.
Crohn's disease is a chronic inflammatory bowel disease characterized by an inflammation immune response to tissue that causes redness, swelling and pain of the digestive or gastrointestinal tract.
to as colitis, enteritis, ileitis, and proctitis. When you have this disease your body’s immune system begins attacking healthy cells in your digestive tract, and this is what causes the inflammation. Crohn’s disease is one of the fastest growing intestinal diseases in the United States. Although the condition can affect any part of the gut, the most commonly affected areas are the ileum or the large intestine, the colon. Crohn's disease may be mild, moderate, or severe. Most patients are able to lead full and productive lives when treated properly.
The name for these erosions is aphthous ulcers. These erosions, after a while, start to deepen and grow in diameter. Once they reach a certain size, they can be referred to as ulcers. These ulcers can cause scarring and they can also cause the bowel to become stiff and lose its elasticity. As Crohn’s worsens, the bowel becomes obstructed once the passageways narrow enough. This obstruction can cause a buildup of food that is still being digested, fluid and gas that comes from the stomach. This obstruction will then prevent all of those products from entering into the colon. This will cause severe abdominal cramps, nausea, vomiting, and even abdominal distention. If the ulcers located in the walls of the bowel become large or extreme enough, holes can form in the walls of the bowel. Once those holes are formed in the bowel, the bacteria normal to the bowel can then pass through those holes and spread to nearby organs and into the abdominal cavity causing what are called fistulas. These fistulas are like a channel/tunnel that is formed between the ulcer and the adjacent organ. Then when a fistula is created between the affected intestine and the bladder, it is called an enteric-vesicular fistula which can lead to UTI’s and feces being presented during urination. Next, when the fistula is formed between the intestine and skin, it is called an enteric-cutaneous fistula. What this fistula, pus and mucous exit the body through a painful opening found in the skin of the
As mentioned earlier, it is fundamental for the health practitioner to know the severity of the disease in order to decide an appropriate treatment.1 One of the tools that are often used to assess the severity of CD is the Crohn’s Disease Activity Index. (CDAI).11 It determines the current severity of CD based on the patients’ signs and symptoms of the past 7 days.11 CDAI score less than 150 is a marker of remission (no active inflammation and has no symptoms of CD) of Crohn’s disease.11 In the meantime, CDAI score more than 450 is a marker of severe Crohn's disease and usually warrant a rapid investigations.11
I would suggest that you stop eating lipids in your diet, go for a healthy diet full of fruits and fibers.
Ulcerative colitis is a disease that causes inflammation and sores, called ulcers, in the lining of the rectum and colon, also known as the large bowel. The inflammation may be taking place in the whole colon consisting of the pancolitis and ulcerative proctisis or perhaps somewhere in between the two. Ulcers form were inflammation has killed the cells that usually line the colon, then
Colitis was quantified with a clinical score by assessing the weight loos, stool consistency and bleeding of the colon (measured by guaiac reaction, hemoccult) as per cooper 10. If there was no weight loss, then it was assumed and counted as 0 point and weight loss of 1 to 5 % as 1 point, 5 to 10 were given for well-formed pellets, 2 points for pasty and semi formed stools that did not stick to the nus, and nt, 5 to 10 as 2 points, 10 to 20 % as 3 point, and 20% as 4 point. For stool consistency, the stool were collected in a thick paper and observed, 0 point were given for well-formed pellets, 2 points for pasty
especially in the colon. This drug can be used for as long as needed, and it
Inflammatory bowel disease (IBD) can be defined as the chronic condition (it is persistent/ long-standing disease) resulting from inappropriate mucosal immune activation. Inflammatory bowel disease (IBD) can start at any age. However, it is frequently seen among teenagers And also among young adults in their early twenties, both genders can be affected by this disease. There are two conditions that traditionally comprise inflammatory bowel disease (IBD): Ulcerative colitis and crohns disease. Comparison between Ulcerative colitis and crohns disease are clinically useful, because distinguishing between the two conditions allow specialists to choose the right management way. Comparison between Ulcerative colitis and crohns disease are
While Ulcerative Colitis and Crohn’s Disease share similar symptoms, they are treated different medically. “There are cases where the diagnosis of one form of Inflammatory Bowel Disease over the other is very difficult.