Cause. Systemic Lupus Erythematosus Is Complex Autoimmune

Lupus is a chronic inflammatory disease of unknown cause that can affect virtually any part of the body. The medical term for Lupus is Systemic Lupus Erythematosus or better known as SLE. With Lupus there is a malfunction in some of the cells of the immune system. "In Lupus, the body overreacts to an unknown stimulus and makes to many antibodies, or proteins directed against body tissue. Thus, Lupus is called an autoimmune disease. ”#

Lupus is an autoimmune disease that attacks women between the ages of 15 and 40. It occurs less often in men than in women. The people affected by lupus vary depending on the country or region. In the US alone, the prevalence rate is highest among Asians of Hawaii, blacks of Caribbean origin, and Native Americans of the Sioux, Arapahoe, and Crow tribes. Lupus is a disease that affects the immune system. We can think of the immune system as an army within the body with hundreds of defenders (known as antibodies). They defend the body from attack by germs and viruses. In lupus, however, the immune system becomes overactive and creates antibodies that attack healthy tissues in the body, such as: the skin, kidneys, lungs, heart and brain.

Systemic lupus erythematosus, or simply lupus is a chronic autoimmune disease or immune system malfunction. A person's immune system normally protects the person from viruses, bacteria and other foreign materials. When a person has an autoimmune diseases like lupus, the immune system turns against itself and attacks itself.

ANA: test for these autoantibodies (very general); DsDNA (+): Making antibodies to and attacking own DNA; Anti-Sm (+): these antibodies generally interfere with the cells metabolism and are responsible for the symptoms specifically seen with SLE. Here, they are specifically targeted at smooth muscle. CRP elevated: also indicates presence of inflammation, but is more specific towards disease activity; ESR elevated: indirectly indicates the activity of the disease and presence of inflammation; C3 and C4 (decreased): C3 and C4 usually attack the membranes of viruses and bacteria, but in the case of lupus, they attack the own body’s cells. When C3 and C4 suggest the disease is active

Lupus is a rare and crippleing disease. This disease is as rare as it is hard to undertand. Lupus being a not well known disease is hard to pinpoint. This disease causes insufferable pain and body problems. Such a terrible disease causes syptoms like swelling muscles, joint pains, general inflamations, organ failures, and overall fatigue. Lupus is an autoimmune disease ( AKA the autoimmune sytem attacking itself). This autoimmune disease is most common in youge woman in birth bearing age. With little known reason

Systemic lupus erythematosus (SLE) also referred to lupus dates back to the middle ages and has made an explosion in the past 60 years. Even though more than 1.5 million Americans have lupus and 90% of lupus sufferers are women, between the ages of 15 to 44 (Lupus Research Institute), there is little awareness about the disease. 72% of Americans aged 18-34 have either not heard of the disease or know nothing about it (Medical News Today). However, researchers continue on working to have a better understanding of SLE factors, pathophysiology, current treatment and new prospects for treatment.

Systemic Lupus Erythematosus is an autoimmune disease within the appearance of autoantibodies that fights against nuclear antigens within the body of a person who is living with SLE and the involvement of their organ systems, including the kidneys. The rigorous events that cause an onset of medical signs of SLE are not yet well understood. However, the researcher are usingnumerous mouse strains spontaneous and inducible lupus to find a cure because as of now there still is no cure for lupus.

Lupus is an autoimmune disease where your own immune system attacks not only pathogens, but your own healthy tissue. It is one of the more severe autoimmune diseases and can seriously impair the life of the sufferer if left untreated, possibly leading to death.

Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disorder that can cause significant morbidity and mortality. A large body of evidence has shown that African Americans experience the disease more severely than other racial-ethnic groups. We performed a systematic review in the PubMed and Medline Databases of articles published between January(?) 2000 – December 2014 to evaluate research focused on SLE in African Americans. Articles were classified according to their level of evidence. Our literature review reported a wide range of adverse outcomes in

Systemic lupus erythematosus (SLE) is a disease in which a person’s own immune system begins to recognize its own tissues and organs as foreign antigens which causes it to attack and injure those targeted structures (Perspectives 14). Discoid lupus erythematosus (DLE) causes coin-shaped lesions to appear on the skin and does not affect any other system other than the integumentary (Perspectives 23). As stated on the Mayo Clinic website the etiology of the disease is idiopathic, but it is believed that environmental factors and inherited genetic code may contribute to the formation of lupus. Lupus can also be triggered by sunlight, infections, and medications such as anti-seizure and hypertension prescriptions (Mayo Clinic). Iatrogenic cases of the disease often have their symptoms reduced or eradicated after stopping those medications (Mayo Clinic). Diagnosis of the disease is based upon criteria set in place by the American College of Rheumatology as lupus often affects the muscle and joints (Lupus.org). The list is comprised of eleven common signs and symptoms that have been observed by rheumatologists. They are: Malar or

The cause of Lupus is still an enigma, and this is one chronic condition that still can’t be easily defined.

Grace Spottswood, 1-30-15, Watermelon Lupus: Imagine skiing down the slopes and watching all of the happy people enjoying their ski trip, and wondering, why do I feel so sick? Imagine going to countless doctors' appointments, and being treated for anxiety and facial migraines. No one believes your symptoms are real, but you know something isn’t right. After five years of suffering, you are finally diagnosed with an incurable disease.

Makover, M. & Zieve, D. (2011, February 14). Systemic Lupus Erythematosus. National Center for Biotechnology Information. Retrieved July

Lupus is a chronic inflammatory disease marked by its effect on various parts of the body, including the joints, skin, blood, and kidneys. It is a condition in which the body's immune system attacks its own cells and tissues, resulting in pain, inflammation, and often damage to organs. Lupus involves the immune system. The immune system makes antibodies that work to protect the body against foreign substances like viruses and bacteria. Such foreign bodies are called antigens. When a person has lupus, his or her body is unable to determine the difference between antigens and the individual's cells and body tissues. As such, the immune system creates antibodies against the individual's own tissues. These antibodies are called autoantibodies. Depending on the type of lupus, a wide range of symptoms may be experienced, from rashes, hair loss, and achy, swollen joints to fever, anemia, and abnormal blood clotting. Though the disease can affect many parts of the body, individuals usually experience symptoms in only a few organs. There is no known cure for lupus. However,

Systemic Lupus Erythematosus is a chronic autoimmune disease which causes inflammation of your joints, tissues, and organs. The inflammation presents itself as heat, pain, swelling and redness. SLE is a variable disease that doesn’t take any one particular course; therefore its unpredictability makes it even more devastating. No two people will experience the same disease symptoms or severity level. As S.L.E progresses there will be periods of very subtle to no symptoms at all called remission or an exacerbation of symptoms called flares.