Causes And External Factors Of Extrinsic Ageing

Skin aging is a process that naturally occurs in human beings from birth and is different in each person due to intrinsic and extrinsic factors. To find out what has the most influence on the human skin, both factors need to be fully researched. You can also look at other details to do with skin aging like the process of it, the appearance of it and how it can be prevented. Both factors will be covered as both are completely different processes of the skin aging. It would be true to say that not all 70 year old females have the same skin, as many factors will affect how the skin of a 70 year old could look.

In today's world, there is a large amount of emphasis on physical beauty, youth, and how to stay younger for longer. Although many have condemned this as a particularly shallow approach to life, there is also an underlying concern for physical health, which is at the bottom of longevity and a concomitant better-looking physique. Indeed, the longer a person can maintain a healthy lifestyle and a focus on self-care, the longer he or she tends to maintain a relatively youthful or at least healthy demeanor. This has also become a growing concern as life expectancy has increased almost exponentially for human beings over the last century. For this reason, companies such as Dr. Perricone MD Skincare continue to do extensive research to determine ways in which the longevity and youth of the skin can be prolonged and even restored.

Also, three primary structural components of the dermis, collagen, elastin and GAGs have been the subjects of the majority of anti-aging research and efforts for aesthetic-anti-aging strategies pertaining to the skin, from “anti-wrinkle creams” to various filling agents.

The elderly population is growing rapidly and now makes up greater than thirteen percent of the United States population. (APA, 1994). With such a record growth, there are different aspects to aging that are still being analyzed. Many may think of reaching late life as a rite of passage, but many face this time with a different view. Through the movie "UP', we are granted an opportunity into view the struggles of an elderly widowed man by the name of Mr. Fredrickson and the challenges in which he faces in his later life. The movie, takes one on a journey through his sorrows and his triumphs until he realizes what the true meaning of happiness is.

A variety of factors contribute to the signs of aging on the face. These factors include a decrease in the production of collagen, the constant pull of gravity, stress, genetics and various environmental factors (including exposure to UV light).

This paper will discuss the relationship between the aging process and key diseases associated with aging. Examples of aging-associated diseases include cancer, diabetes, cardiovascular disease, and neurodegenerative diseases (López-Otín, Blasco, Partridge, Serrano, & Kroemer, 2013, p. 1194). Of these, we will discuss in-depth recent studies that have linked aging with Alzheimer’s disease, cardiovascular disease, and diabetes. These diseases affect a significant proportion of the population over the age of 65 and place a considerable burden on the American health care system. Therefore, a better understanding of how they are related to aging and each other can result in the adoption of innovative treatments and declined risk for older adults.

Age- related changes that happen in the epidermis are more likely to occur in sun exposed areas of the body. As one ages, the epidermal thickness decreases, however, the number of cell layers remains about the same. The skin’s ability to act as a barrier against loss of body fluids or entry of substances through the skin is essentially stable. The dermis does decrease in thickness in older age, causing the skin to appear extremely thin and transparent. Collagen decreases in the skin, and elastin fibers thicken. Increasing in size, the sebaceous glands enlarge, while the sebum (oil production) tends to decrease. As one begins to age, the normal “shivering” reaction tends to decrease, as does vasodilation and vasoconstriction in response to heat and cold. Therefore, ones sweating response is reduced, and a lower metabolic rate is created due to less body mass in the individual. In the hypodermis, the layer of fat cells become thinner with age, and diminishes both protection and insulation. The protection of the hypodermis avoids trauma, while the insulation of the hypodermis prevents loss of body heat (Saxon,

show several aging-dependent changes such as changes in anatomy and function in identified neurons [8], behavioral changes [9,10], expression of mRNAs [11], and neurotransmitter regulation [12]. (2) A simple and well-studied nervous system and behavioral repertoire to facilitate the study of neurological and behavioral correlates of aging at the level of single neurons and circuits. (3) Two learning assays (Sensitization and Habituation of the GWR) proposed in this study are well studied and show age dependent decline [9]. (4) Importantly, neural circuitry underlying GWR has been identified [5]. Neurons of Aplysia GWR offer several advantages. In contrast to Drosophila, C. elegans or mammalian neurons, those of Aplysia are gigantic, allowing relatively easy study of cell-specific changes during aging. Importantly the presynaptic sensory (LESN) and postsynaptic motor (L7MN) neurons of the GWR circuitry can be easily identified (Fig 1) and manipulated. Sensitization of GWR result in growth of new synaptic connections, whereas habituation induces retraction of synapses. Thus, the experimental system allows for precise measurements of electrophysiological, morphological and molecular changes to address the specific aims of this proposal. (5) As described in the “Significance” section it is important to recognize that many concepts that are central to our overall understanding of the LTM were established using Aplysia [5, 13-17;18-23]. Therefore it is expected that

There are many reasons the skin gradually ages, including the natural aging process where skin becomes thin and more susceptible to gravity and genetics. This is called intrinsic aging and is unavoidable. However, there are extrinsic reasons why the skin ages and the ultraviolet (UV) rays from the sun account for 80 percent of extrinsic skin ageing according to studies reported in the Clinical, Cosmetic and Investigatory Dermatology medical journal.

The most distinctive qualities of younger looking skin is its ability to stretch and then return to its previous state. Imagine invisible rubber bands that pull the skin back. However, as we age, those rubber bands weaken, and the skin becomes loose. Since the law of gravity is the one we all have to obey, our skin eventually begins to sag. As time goes on, the laughter lines and fine wrinkles become more prevalent and can affect how we feel about ourselves.

Aging process will lead to decline of biological functions and the ability to adapt to metabolic stress. Since the percentage of mortality increases rapidly with aging, it is clear that all of the body systems will changes in the individual which make him or her more vulnerable to disease. Among the systems that get affected by aging process are endocrine, cardiovascular, respiratory, musculoskeletal, and reproductive

As we age, most people can point out the physical signs of aging that gradually begin to appear on a person’s face. This can be anything from the graying of hair to having wrinkly skin. With most people only knowing the signs on the surface, it is important to also watch for what is happening on the inside of our bodies. It is the internal changes that occur during the aging process that are the most important to be aware of to prevent any rapid deterioration of the body and mind.

Aging is the process of becoming older, as we age, multiple mutations occur that concern all the processes of aging well as it compromising a number of different genes. There are many theories of biological aging, such as the Cellular Aging Theory, Immunological Theory, and the Wear and Tear Theory. The Cellular Aging theory describes the process of aging in which cells slow their number of replication, thus giving each species a “biological clock that determines its maximum life span” and how quickly one 's health will deteriorate(Hooyman, 42). After a certain number of years, each cell which follows an apparent biological clock starts to replicate itself less, thus the specific individual or species slowly deteriorates. This theory gives

With the growing age, Hyaluronic Acid (HA), natural collagen and elastin of our skin reduce. As a result, our skin leaves its normal support and get dried up. It tends to develop fine lines, patchy skin, and wrinkles.

Causes of aging are very uncertain. Besides, there are several factors which predispose an individual to premature aging. Current theories suggest that this process occurs to due to cellular damage such as DNA oxidation by free radicals causing