Causes And Symptoms Of Hantavirus Pulmonary Syndrome

EH is a 68-year-old male who comes into the clinic complaining of a fever with a temperature of 103 °F. He has had a cough for the last three days that is producing some thick green brown mucous. The MD feels he most likely has bacterial pneumonia. He also has a history of having rheumatoid arthritis, and being immune compromised as he is on an immunosuppressant methotrexate. He has noted that over the last year he has lost weight unintentionally and feels he is underweight.

Patient’s WBC were on the normal parameter (11.6). Patient did not present signs and symptoms of

Everyone listen up, it is now time to take caution. A virus has re-emerged and is spreading fast. We first saw a case like this in 1994 where well-known horse trainer, Vic Rail died after 6 days and experienced severe lung inflammation, interstitial pneumonia and respiratory failure (Grant,2013). 14 of his horses also died when it broke out not far from here, in fact Hendra and now it has come back to haunt us with its lethality (Betterhealth.vic.gov.au, 2015).The emergence in humans was unprecedented and shocking.

A two month old African American child was admitted to a local clinic in Bakersfield, California with a cough, fever, and occasional night sweats. The physician diagnosed him with influenza B virus and sent him home with some acetaminophen(brand name Tylenol) to help with the symptoms. At home, the boy progressively got worse so after three days, the child was readmitted to the clinic. The physician had a blood test and a sputum test sent to a microbiologist for examination as the doctor believed that the child was infected by another microbial pathogen. After examining the blood and sputum, it became clear that the child had an infection that was much more dangerous than influenza B.

“Influenza (Flu).” Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, 31 July

The patient is a sixty-seven-year-old Somali female, whom will be referred to as Jane. Jane initially presented to the emergency room with shortness of breath, fever, tachycardia, and a persistent cough. She has a history of tachycardia and asthma. The goal for the treatment of this patient was to rule out avian flu, and to manage her tachycardia and asthma.

Jane was not showing any signs or symptoms of complication until about four months later. She began to experience recurring headaches, fatigue, decreased appetite, and losing weight, fever and complained of a sore throat with white patches developing. Her neck lymph nodes were also showing signs of swelling. Her Physician immediately ordered an Enzyme-Linked Immunosorbent (ELISA) test, Western Blot testing, CD4 T-cell count, Complete Blood Count (CBC), Erythrocyte Sedimentation Rate (ESR), and a p24 Antigen test and was asked to come follow up when the results where in.

A common test performed when trying to diagnose respiratory infections is a chest x-ray. When looking at the results of the x-ray in the case study there was interstitial fluid found in the lungs. Looking at Catherine Goodmans text Pathology, PCP is described as cysts that grow and burst with fluid, and giving way to more cysts that continue the cycle. These cysts and their bursting could lead to the fluid found in the x-ray. When looking at TB, the textbook states that the most common things seen in an x-ray would be atelectasis(a burst lung), lesions forming on the lung surface, and solid masses. None of these fit the description. In addition the patient did not mention a prolonged and slowly progressing case. Tuberculosis is noted to work

Qiana “Nikki” Little was born on February 8, 1992 to Evelyn and Quentine Little.Only being on this planet for a week something happened, “She was laying down sleep and I knew something was wrong. She was having problems waking up,” said Evelyn. With a very high fever Evelyn and Quentine rushed her to the hospital. This is where she spent ten days in the hospital; three in ICU and and seven in a oxygen tank. That’s when the family found out that Nikki had a serious infection called RSV.

Sequential patchy lobar infiltration progressing to consolidation is observed, though diffuse interstitial infiltrates are also seen. Pleural effusions are common as well. Radiographic anomalies progress often upon reception of active antibiotic therapy; therefore, radiographic improvement precedes clinical response by many days. Chest radiograph unrevealing in Pontiac fever. [12 I]

Based off of the clinical symptoms as well as the lab workup, I believe this patient has an acute infection with mononucleosis caused by Ebstein-Barr Virus (EBV). The patient’s white blood cell count is decreased at 2, and has an elevated band count indicating an infection is present. Furthermore, the EBV VCA IgM and IgG indicate a present EBV infectious mononucleosis (IM) (Mayo Clinic, 2017). It is not uncommon for the monospot test to be a false negative. The patient has the classic triad symptoms of mononucleosis along with a positive antibody test indicating a current infection (Mayo Clinic, 2017). If the patient had an elevated EBV VCA IgG without a positive IgM that would indicate a past exposure to infectious mononucleosis caused by

In 1967 Asbough and colleagues observed a severe lung disease which developed in ICU patients suffering with severe shortness of breath, loss of lung by bacterial microorganisms this also serves as a major contribution in the field of sepsis.

As the patient lacks antibodies, these infections can be dangerous as they can spread to the bloodstream and invade deep into the organs within the patient’s body, for example his joints, bone or even his brain. These recurring infections are caused by a microorganism in which in a normal healthy body are normally disposed of and inactivated by the antibodies very effectively, and this is due to the defect of lack of B cells that is present at birth in XLA patients.

We did initially have her on antibiotics to cover the possibility of of a bacterial lower respiratory tract infection, but given that there was noting grown on sputum and the RSV seen on the nasopharyngeal swab, this was stopped while she was an inpatient.

"The common clinical features among the case-patients included a prodromial illness of fever, chills, and myalgia. The prodrome was followed by dyspnea, cough, throbocytopenia, severe hemodynamic instability, neutrophilid with immature forms, atypical lymphocytes, elevated serum levels of lactate dehydrogenase. There was a high mortality rate, approximately eighty percent in the initial group of patients, the chest x-ray examinations revealed a diffuse, interstitial infiltrate that resembled that observed in patients with adult respiratory distress syndrome (ARDS), which is a common pattern in patients