Causes And Treatment Of Pancreatic Cancer

This year, an estimate of 53,070 adults, have been or will be diagnosed with pancreatic cancer. (27,670 men and 25,400 women). Pancreatic cancer is the ninth most common cancer in women. Pancreatic cancer should have the most attention because doctors still don’t know how to diagnose this type of cancer yet. The main problem is cost-effective screening tests that easily and reliably find early-stages of pancreatic cancer in people, sometimes show no symptoms.Often “times it is” not found until later stages when the cancer can no longer be surgically removed and has spread from the pancreas to other parts of the body. ("Pancreatic Cancer: Statistics", 2017)

Pancreatic Cancer is cancer of an organ in the human body called the pancreas, which is located behind the lower part of the stomach. The function of this organ is to secrete certain essential enzymes to digest food and also secrete hormones to metabolize sugars such as insulin and glucagon (Mayoclinic). People get pancreatic cancer when the cells of the pancreas develop genetic mutations; and these can form in both the exocrine and endocrine cells of the pancreas, but exocrine tumors are more common than endocrine tumors. Because this cancer spreads very quickly throughout the body and the symptoms of the disease don’t usually appear until the cancer is at an advanced stage, it is a leading cause of death

Pancreatic cancer is the cancer that appears quickly and many die just as quick. Pancreatic cancer is the least known cancer to the medical world; puzzling doctors because most are not sure what diagnosis to look for. However, the risk factors include smoking, diabetes, and obesity. Studies show that pancreatic cancer has a higher percentage in the African American community due to environmental risk factors (John Hopkins Pathology, 2012).

Pancreatic Cancer Axia College (2009) Pancreatic cancer is an abnormal, uncontrolled growth of the cells in the pancreas, which is a digestive gland located behind the stomach. The pancreas is both an endocrine and exocrine gland. Cancer of the exocrine pancreas is more common than cancerof the endocrine pancreas. Pancreaticcancer is the fourth leading cause of cancer related deaths among men and women. Pancreatic cancer remains both a challenge to diagnose and even a greater challenge to treat effectively. What is the pancreas? The pancreas is a spongy, tube-shaped organ about six inches long. The pancreas is located in the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen. The

The pancreas is an organ in the abdomen that sits before the spine over the level of the belly button. It performs two important things. First off, it makes insulin, a hormone that regulates glucose levels; secondly, it makes compounds which help separate proteins. The chemicals help digestion by breaking proteins into littler parts so they can be all the more effortlessly digested by the body and utilized for vitality. Proteins leave the pancreas through an arrangement of tubes called "ducts" that associate the pancreas to the digestion systems. The pancreas sits somewhere down in the stomach and is in close vicinity to numerous important structures, for example, the small intestine (the duodenum) and the bile pipes, and in addition critical veins and nerves.

There are many forms of cancer. Breast Cancer, Lung Cancer, Leukemia, and Brain Cancer just to name a few, but the one I am bringing attention to in this essay is Pancreatic Cancer. Pancreatic Cancer is a very aggressive form of cancer and it has many risky factors. Many people do not know those risky factors important information dealing with Pancreatic Cancer and I will explain a few of those important things in this essay. The American Cancer Society and the Cancer Treatment Centers of America gave me a lot of information to help write about this topic.

I am a lucky yet unlucky man. They call it PanCan, short for Pancreatic Cancer, there are many stages I must say yet there are relatively 20% survival rate and to get to live up to five years? 6% chance. The larger my tumor gets the less likely it’ll be cured. They give me 2 years top, if I am lucky; but I’ve learned to cope with the cancer. You see even people who have 3-5 cm appear to have been cured by surgery, I have hope. On a daily basis I find myself struggling with daily activities, changes in appearances and even anxiety of the future, and on top of all that, I am constantly anxious about treatment and if it will work. Pancreatic Cancer is cruel and ruthless, it will devour one’s

There are two kinds of pancreatic cancer. There is the endocrine tumors and the exocrine tumors. Endocrine tumors are less common and they affect the islet cells of the pancreas. They tend to be benign and not often become malignant. However the exocrine tumors are much more common and this is what Gene is diagnosed with. Exocrine tumors are often called adenocarcinomas and that means cancer affect the gland cells such as the ducts of the glands (American Cancer Society). Pancreatic adenocarcinomas keep the glands from secreting normal The signs and symptoms of pancreatic adenocarcinoma is darkening of the urine, irritated skin, jaundice, pain in the upper abdomen and back, unexplained weight loss, stomach bloating, weakness, and nausea.

Pancreatic cancer is lethal malignancy with a mortality rate that almost equals its incidence. It is the 4th leading cause of cancer-related deaths in the United States, with only a 5-year survival rate of about 6%. Pancreatic cancer remains to be one of the most aggressive tumors. When diagnosed 60-80% patients already have locally advanced or the tumor has already metastasized. A majority of pancreatic cancers are derived from the exocrine part of the pancreas. The exocrine part of the pancreas produces digestive enzymes that help break down proteins, fats, and starches. There are several mutations that have been identified in pancreatic cancer; these mutations can lead to potential biomarkers, leading towards a better prognosis for high risk patients.

Pancreatic carcinoma (P.C) is a malignant disease of the pancreas and one of the top ten leading causes of cancer deaths in the UK. This type of cancer is one of the few which has shown a small improvement in the survival rate. On average, the age at which patients are diagnosed with such disease is at 71 years of age and with a minimum of 40 years old in rare accounts. Whilst the risk of developing such disease is greater in developed than developing countries, various factors either lifestyle factors or hereditary can metamorphose into risk factors and become cancer causing. The pathophysiology of this type of cancer is complex and involves modification of the DNA by various ways such as point mutation, indels, gene rearrangement and more. Early diagnosis of pancreatic cancer is difficult as it is an organ found quite deep in the body so any anomalies co go unnoticed during routine examinations. The incidence aswell as the mortality of

The risk of developing pancreatic cancer is lower among non-smokers, and people who maintain a healthy weight and limit their consumption of red or processed meat. A smoker's chance of developing the disease decreases if they stop smoking, and almost returns to that of the rest of the population after 20 years. Pancreatic cancer can be treated with surgery, radiotherapy, chemotherapy, palliative care, or a combination of these. Treatment options are partly based on the cancer stage. Surgery is the only treatment that can cure the disease; it may also be done to try to improve quality of life without the potential for cure. Pain management and medications to improve digestion are sometimes needed. Early palliative care is recommended even for those receiving treatment that aims for a cure.

Pancreatic cancer is when cancer cells form around the the tissue in the pancreas. It is located in your stomach in front of your spine. What the pancreas does for you is it makes the liquid and the hormones that help make your blood sugar normal. For the most part the start of pancreatic cancers start in the exocrine cells. Pancreatic cancer has a poor judgement that might happen in the future. It spreads very fast and not seen in the earlier stages. That is one reason this is one of the major cancers that leads to a lot of people's

In the pancreatic cancer, overall 81.3% of all patients showed up regulation of WNT5A. (18) Similary to the melanoma, patients with higher level of WNT5A expression tend to have worst tumor histological grade. It is believed WNT5A increases cancer cells migration and invasiveness both in vitro and in vivo. (18)

Methods In the retrospective study, advanced pancreatic cancer patients were treated as the GS regimen (gemcitabine 1000mg/m2 I.V for 30min on days 1, 8, and S-1 80mg/m2 per day orally for 14 consecutive days, followed by a 7 days rest period, repeated every 21 days). The cycle was repeated until disease progression or unacceptable toxicity.

Cancer, called malignancy as well, is a class of diseases described by out-of-control cell proliferation. According to the announcements of World Health Organization (WHO), cancer is the second leading reason of death worldwide (around 13% of all deaths in 2008). The disease arises from a transformation that occurs in one normal single cell in a multistage process towards tumorigenesis. Management is not accomplished with a single therapeutic; patients often get a combination of therapies dependent on the type and stage of cancer. Predominantly, management of cancer includes the utilize of several modalities of therapy including: palliative care, chemotherapy, radiation, surgery, gene therapy, hormone therapy and immunotherapy 1.