Causes Of Cancer Research And Genetic Development Of Ceervical Cancer

In addition, the immune system of most women will usually suppress or eliminate HPVs. This is very important because only an ongoing persistent infection has the potential to lead to cervical cancer (HPV). Eleven thousand cases of this kind of cancer were confirmed in 2007 in the United States; the amount undiagnosed is still unclear but believed to be in the tens of thousands. But to give some perspective of the problem you need to understand its effects on a global level. On the world wide scale cervical cancer strikes nearly half a million women each year, claiming more than a quarter of a million lives. “High risk” HPV types 16 and 18 are implicated in Seventy percent of cervical cancers and are hence selected for vaccine targets (The HPV).

Almost all cervical carcinomas are caused by Human papillomavirus (HPV). Cervical cancer can be a life-threating disease. However, over recent years the occurrence of cervical cancer has declined as well as the chance of dying from it. A huge contributing factor to this decline is the importance of a regular pap smear. A pap smear can find cervical pre-cancer before it turns into cancer. Recently, a vaccine for HPV, has been on the market, which provides close to a 100% protection against pre-cancer and general warts. HPV and cervical cancer are two disease that are closely related. However, each disease effects not only similar populations, but also different populations, as well as having its own signs and symptoms, detection procedures,

HPV is the number one sexually transmitted infection (STI) in the United States, and anyone who is sexually active is at risk of contracting the virus. HPV is transmitted through intimate skin-to-skin contact with someone who has the virus, and it is so common that most all sexually active men and women encounter a strain without ever knowing they’re infected (CDC). There are many strains of the HPV virus, some of which don’t cause cervical cancer. To help understand and classify the types of HPV, the terms low-risk and high-risk HPV are used. Some

The controversial debate regarding the safety of vaccinations continues to captivate the masses; however we must understand whether the side effects from the vaccine outweigh the risk of the disease it may prevent. There is only one way to prevent the disease cervical cancer, and that is through examination, not vaccination. The vaccination available to aid in prevention of cervical cancer has some effectiveness and in many cases ineffectiveness, in preventing Human Papillomavirus. In essence, the most reliable method of prevention is regular visits with your physician.

Cervical cancer is a type of abnormal and malignant cell growth on the cervix (birth canal), which causes the common death for American Women. Infected by Human Papillomavirus (HPV) through sexual contact is the main contributor to cervical cancer. According to American Cancer Society’s (ACS) (2017) estimation, around 12,820 people will newly have cervical cancer and about 4,210 people will die from that in 2017. Therefore, it is urgent to decrease the rate of cervical cancer at women. A three-shot Gardasil series vaccine approved by the FDA for girls started to prevent cervical cancer in 2006. There are more than forty types of HPVs and the majority

According to the Centers for Disease Control and Prevention (CDC), Human papillomavirus (HPV) infects roughly 20 million individuals in the United States with 6.1 million new cases each year. There is no cure for HPV, only treatment for associated health problems. There are more than 30 strains of HPV that affect more than half of sexually active individuals in their lifetime. Public health risks involve several types of HPV leading to precancerous lesions and causing 70% of cervical cancer. Cervical cancer, the second most common cancer, affects many women globally. In the United States, nearly 10,000 women are diagnosed with cervical cancer annually and 3,700 of those women die. It has been reported by American Cancer Society that with early

Approximately 500,000 new cases of cervical cancer occur each year worldwide, 260,000 of which are fatal. In the U.S., it is estimated that there were over 9,700 cases of cervical cancer in 2006, and of these 3,700 resulted in deaths”. Vaccinations are one of the most successful public health approaches to preventing and controlling infectious diseases. According to the CDC Advisory Committee on Immunization Practices the vaccine has been proven to be virtually 100% effective against the two types of HPV that are responsible for some 70% of cervical cancers.

In US cervical cancer is ranked 13th most common cancer in women and 4th among women between 15 to 44 years.

Did you know there is more of a link between cervical cancer and HPV than smoking and lung cancer? Cervical cancer is currently the fourth most common cancer in women and the second leading cause of death from cancer in women. Along with those statistics, human papillomavirus is the most common sexually transmitted viral disease amongst men and women worldwide. The prevalence of women having a strain of HPV that ultimately leads to or increases the chance of cervical cancer is highly relatable. What is pathophysiology, signs, symptoms, prevention, and treatments of this ailment? You might ask will be covered in the next few pages of this paper.

Human Papillomavirus (HPV) is a double -stranded deoxyribonucleic acid (DNA) virus that only infects humans with an attraction to both cutaneous and mucosal surfaces such as the cervix, anus, tonsil, and oropharynx (Clark, 2013). HPV is a type of oncogenic virus that goes into the cells and can cause several diseases. Over the years, research has surfaced connecting genital HPV to several types of cancer. There are over a hundred strains of HPV but the most high risk strains, 16 and 18, have been shown to cause vulvar, vaginal, anal, and the most concerning, cervical cancer (Chan, Ng, & Wong, 2012). Genital HPV

Cervical cancer is formed in the tissues of the cervix, an organ that connects the uterus and the vagina. Virtually all cervical cancers are caused by Human papillomavirus (HPV) infections (Schiffman et. al., 2007). HPV is the most common sexually transmitted infection in the United States. According to the CDC, 75% of sexually active people aged 15-49 have the infection at some point in their lives. (CDC). Because HPV infection is usually asymptomatic, infected people do not know exactly when they get the infection. In most cases, the body is able to fight off the virus before any symptom. However, health problems such as genital warts and cancer may

Human Papilloma Virus (HPV) is the most commonly diagnosed sexually transmitted infection in the United States (Ault, 2006). Almost all sexually active men and women will contract HPV at least once during their lifetime (What is HPV?, 2015). Sexually active women below the age of twenty-five consistently have the highest rates of infection (Ault, 2006). The development of the HPV vaccine in 2006 has decreased the prevalence of infection from 11.5% to 5.1% among females ages 14 to 19 (CDC, 2015). High-risk strains of HPV are also “detected in 99% of cervical cancer cases” (Valdez, Stuart, Tanjasari, Levy, & Garza, 2015, p. 106). Therefore HPV infection is one of the most significant risk factors in the development of cervical cancer.

The human papilloma virus (HPV) is the most common sexually transmitted disease, with a worldwide point prevalence of 11.7%., in the United States over 79 million people are already infected with HPV, and over 14 million new HPV infections occur each year CITE 1,2,5. HPV affecting both men and women, has an estimated lifetime prevalence of 80-90%, it is likely that most sexually active people will become infected with HPV before the age of 45 CITE 1, 3. Although over 100 HPV genotypes have been identified, only 40 infect the genital area. These 40 are further subdivided into high risk oncogenic genotypes, and low risk the genotypes responsible for genital warts and recurrent papillomatosis CITE 8,3. HPV is associated with virtually all cervical cancers, and over 90% of anal cancers CITE 1. The cost of preventing and treating HPV and its associated diseases is estimated at eight billion dollars annually

Cervical cancer is the only malignant tumor that can almost completely be prevented by safe, fairly simple and affordable means, and yet, one woman dies of this disease unnecessarily every two minutes in the world. Cervical cancer is the most common malignant tumor of the female reproductive system in the developing world and the leading cause of cancer- related deaths in sub- Saharan Africa. Cervical cancer is the most frequent cancer diagnosed in Tanzania and its mortality rate is unacceptably

Moreover, preliminary data show that deletion of RRM2, but not the RS domain, results in decreased MALAT1/SRSF1 interaction and that MALAT1, SRPK1 (SRSF1-specific kinase), and SRSF1 also form a complex. This scientific literature and empirical evidence regarding the relationships between SRSF1, p53, OIS, and MALAT1, when taken together, have led us to our central hypothesis that MALAT1 overexpression disrupts the interaction between the RRM2 and RS domain in SRSF1, subsequently impairing SRSF1 RS domain phosphorylation and thus its nuclear translocation. This change in subcellular localization, in turn, destabilizes p53, leading to loss of OIS in HPV-negative cervical cancer (HNCC). Our goal is to examine the differential expression and biological importance of MALAT1 in HNCC and its consideration as a useful therapeutic target.