Causes Of Huntington's Disease

Huntington's Disease is a genetic autosomal disorder which effects the brain. It affects about 1 in 20,000 individuals. The symptoms of the disease do not start to occur until after or around 40 years of age. With the onset of the disease the patient starts to gradually deteriorate intellectually, this deterioration also causes involuntary movements. Scientists have only recently found the section of the gene which causes Huntington's disease, and this is allowed them to devise pre-symptomatic tests. However, a cure for the disease is yet to be found.

Huntington's Disease (HD) is an autosomal dominant, progressive, neurodegenerative disorder (Walker, 2007 and Harmon, 2007). The gene that causes the disease is located on the fourth chromosome and causes an abnormal number of repeats in the patient's genetic code (Harmon, 2007). Huntington's Disease can have devastating effects on patients' quality of life. The first symptoms of HD generally start between the ages of 30 and 45 and patients are typically asymptomatic prior to this time (Terrenoire, 1992 and Walker, 2007). However, the disease progresses with subtle changes in motor control, personality, and cognition. Patients eventually develop distinct

Huntington's Disease is a devastating and progressive neurological disorder that resu lts primarily from degeneration of nerve cells deep in the center of the brain. The condition was first described by George Huntington, a physician in New York, in 1872. Even then, the physician recognized the all-encompassing factors of the disorder when describing it as, "coming on gradually but surely, increasing by degrees, and often occupying years in its development until the hapless sufferer is but a quivering wreck of his former self".

Huntington’s disease is a neurological (nervous system) condition caused by the inheritance of an altered gene. A neurological disorder is a disease that can affect the central and peripheral nervous systems. Huntington’s disease is an incurable genetic brain disorder. The disease is an autosomal dominant disease, meaning a child only needs to inherit the gene from one parent to develop Huntington’s. Nerve cells become damaged when someone holds the HTT gene that produces a protein called huntingtin, as too much of this protein damages cells, and causes various parts of the brain to gradually deteriorate. Huntington’s disease causes changes in the central area of the brain, the basal ganglia, which can affect movement, emotions, and mental

Huntington’s disease is a degenerative neurological disorder affecting movement, cognition, and emotional state (Schoenstadt). There are two forms of Huntington’s disease (Sheth). The most common is adult-onset Huntington’s disease, with persons usually developing symptoms in their middle 30s and 40s (Sheth). There is an early onset form of Huntington’s disease, beginning in childhood or adolescence, and makes up a small percentage of the Huntington’s population (Sheth). Huntington’s disease is a genetic disorder with a short history, a plethora of symptoms, and devastating consequences, with no current cure in sight.

Huntington’s Disease is a disorder in the brain that has an impact on the way people talk, think, and move. The disease kills off cells in the part of the brain that controls movements, emotions, and cognitive ability, which is called the basal ganglia. The brain cells of people with Huntington’s Disease build up lots of protein that eventually turn toxic, and cause the cells to die over time. People with this disease can lose up to 25% of their brain cells before they die!

Huntington’s disease (or Huntington’s chorea) is a hereditary degenerative disease that affects the cerebral cortex and basal ganglia. It is a progressive brain disease that targets the ability to move, loss of the ability to think, and emotional problems. The most common form of Huntington’s is adult onset, appearing in the thirties or forties. As the disease advances,

For our gene and protein lab, my group decided and I to research the deadly, yet rare, disease, known as Huntington's disease. Huntington's disease is an extremely rare condition when your nerve cells in your brain break down overtime. Also, “HD” has a treatment that could aid someone, but it unfortunately cannot be cured. Huntington’s Disease typically begins when someone is thirty or forty years of age and can last years to a life time.

Huntington's disease is a neurodegenerative hereditary condition which causes problems in muscle coordination, behavioral symptoms and leads mental deterioration (Hammond and Tatum 2010). Symptom varies among persons of same family. The most punctual side effects are frequently unpretentious issues with state of mind or insight.

The following paper will cover a description of Huntington’s disease and the symptoms that go along with it, how to test for Huntington’s disease, a case study, what gene is involved, the chances of

Huntington's Disease is an inherited autosomal, dominant neurodegenerative disorder. The disease is characterized by a gradual worsening of neuromotor function, mood stability, and cognitive function. Manifestations include: chorea (disordered, involuntary movement), worsening behavioral changes, impaired gait, all leading to complete loss of cognitive faculties, loss of voluntary movement, speech/communication deficits, inability to perform ADLs, dysphagia, dysarthria and dementia. Onset of the disease is around 35 – 40 years of age. Death usually occurs within 10 - 15 years of this onset18.

This paper discusses one of the most well known neurodegenerative diseases named Huntington’s. Recent statistical records showed that the disease is widely spread around the world. Scientists have conducted many researches in order to study the mode of inheritance of the disease as well as to find a possible cure for it. They discovered that the disease is genetically inherited from one generation to another. The aim of this scientific paper is to provide information about this genetic disorder including its history, genetics, inheritance, mechanism, causes, symptoms, diagnosis, treatment and some of the current researches being conducted to study the nature of this disorder. Huntington’s disease has garnered a lot of attention in the last

Huntington disease is a degeneration of the nervous system. It usually occurs in the older part of someone life. As the disease becomes worse it could cause uncontrollable movements in the body. Because the disease causes loss of brain cells, a person can lose memory. It can also contribute to depression. It takes about to ten to twenty years after the first signs of the disease for death to follow.

Huntington’s disease is a genetic and is passed down through families. (https://www.huntingtonsnsw.org.au/information/hd-facts/causes) quotes that If a parent has the gene, each child has a 50/50 chance of either inheriting or escaping it. They (https://www.huntingtonsnsw.org.au/information/hd-facts/causes) also stated that If a person inherits the defective gene it will eventually become active and brain cells in the body's central nervous system will start to die. This is when a person begins to develop the symptoms of HD.

The Huntington’s Disease is a disease that is an inherited condition in which the nerve cells in the brain break down over time. Huntington’s Disease was discovered in 1967 by Marjorie Guthrie. This disease is caused by the dominant alleles and is a fatal disease, which is followed by a series of medical