Causes Of Polycystic Kidney Disease

Injury to the glomerulus and the tubules presents the onset of Intra-renal failure (Matzke, 2011). Some of the frequent causes for Intra-renal failure are glomerulonephritis; pyelonephritis; and tubular injury. Post-renal failure develops from things like ureteroliths, tumors, or anatomic impediments. Opposite of the acute form, the chronic form has a slow onset that has no early stage symptoms. It is important to know that following an acute episode a chronic renal episode often follows, and at this juncture the damage is irreversible. Glomerulonephritis and pyelonephritis combined, has been reported to be the forerunner in as much as half the cases from acute to chronic renal failure. Diabetes mellitus, renal vascular disease, such as atherosclerosis, hypertension, polycystic kidney disease, drug damage, and nephrolith are all examples of other causes of CKD (Pradeep, 2014). Biopsies of kidneys that suffered with CKD reveal smaller kidneys with scarring on the tubules.

All the symptoms that were described were based on the kidney functions, so more and further

Primary treatments include antibiotic therapy, Fluid resuscitation, and crystalloid. Potential treatments depending on patient status include vasopressors and steroids, ventilator, renal dialysis, blood transfusion, and surgery.

There is no cure for CKD however it can be treated to relieve symptoms and give the patient a better life and to stop the condition becoming worse. During the early stages of CKD treatments can be given by your GP and mainly involve lifestyle changes such as becoming healthy, doing more exercise and taking certain medicines to assist in controlling blood pressure which then prevents further damage to the kidneys. However if the disease gets worse to the point where the kidneys stop working and functioning properly either a kidney transplant or dialysis which will be explained more in D2 more and it can impact a patient’s life a lot.

Medical procedures that people endure that could cause physical and mental pain include blood transfusion, major surgery and organ transplants.

Autosomal Dominant Polycystic Kidney Diseae (ADPKD) is a very common disorder characterized by progressive enlargement of kidneys that show presence of multiple fluid-filled cysts. Extrarenal manifestations include multiple hepatic cysts, cysts in pancreas, spleen, and seminal vesicals and show cardiovascular abnormalities. About 10% of the patients present with intracranial aneurysms and 8% have sub-arachnoid cysts. Renal function declines in about 50% of ADPKD patients by third or fourth decade of life leading to End Stage Renal Disease (ESRD). Its prevalence world-wide ranges from 1/500 to 1/1000. In India about 2.5% of patients with Chronic Kidney Disease (CKD) have ADPKD. Renal replacement therapies are the only available treatment for these patients.

Dan Davis was diagnosed with polycystic kidney disease, a disease requiring a kidney transplant or else a constant treatment of dialysis.

Chronic Kidney Disease (CKD) is a disease that is described as a loss of kidney function gradually over time. As kidney function decreases, the waste collection in the body’s blood becomes high and makes the individual feel sick. This disease can lead to other complications in the body such as anemia, poor nutritional health, high blood pressure, and nerve damage. These complications will begin to progress and show as CKD progresses to advanced stages. Early detection of this disease is essential when it comes to treatment. If CKD is diagnosed early enough the disease progression can be slowed down and managed. This disease will eventually lead to failure of the kidneys

I chose to write about PCOS because I myself suffer from this disease. PCOS is short for Polycystic Ovarian Syndrome. PCOS is a type of disease where your ovaries fill up with follicles filled with fluid (cyst). It causes mainly infertility and type 2 diabetes. This disease is more common in women who are in the reproductive stage. Not only can it cause the infertility and type 2 diabetes, but it can also cause an irregular menstrual cycle and can cause your body to produce more of a male hormone called androgen. Some other things it may cause is depression, anxiety, high blood pressure, sleep apnea, high blood sugar and many other health problems. The cause of this disease has not been yet identified, but it is said one of the ways could be

I’m sorry to inform you that your prospective baby boy has Autosomal Recessive Polycystic Kidney Disease (ARPKD). ARPKD is inherited recessively so you are both most likely carriers of the disease. There is no good way to say this but that means you have a 50% chance of having a child with ARPKD. From our last ultrasound we saw that his kidney was abnormally large for a fetus his age and we believe we’ve also located a cyst. ARPKD causes cysts to grow in your kidney. Cysts a sac that contains fluid and can interfere with the filtering of waste in the blood. The cysts cause the kidney is become abnormally large. Some of the symptoms for ARPKD are: liver scarring, trouble breathing, kidney failure, kidney stones, and high blood pressure. I’m

Polycystic Kidney Disease (PKD) is a genetic disorder primarily affecting the kidneys. It is characterized by growth of numerous cysts on the kidneys (McPhee, Papadakis & Rabow, 2014). The kidneys primary job is to filter the waste products from the blood into urine and ultimately out of the body. The cysts are primarily fluid filled and when they become enlarged, they interfere the normal functioning of the kidneys, leading to enlarged kidney (McPhee et al., 2014). When the enlarged kidney stops properly functioning leading kidney failure. It may take years before the kidneys totally loose function and then require dialysis, which is in only about half of the patients diagnosed with PKD. According to National Kidney and Urologic Diseases Information Clearing House (NKUDIC)(2007), mutations in genes PKD1, PKD2 and PKHD1 cause polycystic kidney disease. Defects in the formation of epithelial cells and their cilium result in cyst formation and obstruction that is followed by destruction of renal parenchyma, interstitial fibrosis, and loss of functional nephrons (McCance, Heuther, Brasher, 2014). The renal, gastrointestinal, cardiovascular and cerebrovascular organs are the most common systems affected by PKD (McPhee et al., 2014).

There are three kinds of ways to test for polycystic kidney disease. They are ultrasound tests, CT tests, and magnetic resonance imaging. There are many ways to treat this disease. They can include simple over the counter pain medications, these are used when symptoms are not too bad. Sometimes, a kidney transplant will be needed if the kidney fails. The only other way to get this disease is from already

There is no cure for polycystic kidney disease. Scientific research, in fact, failed to identify therapies that could be decisive. However your doctor may prescribe drugs or treatment to relieve certain symptoms. You have to treat hypertension with medications with ACE inhibitors or low-salt diet, the same way as kidney failure can be slowed with a lifestyle healthier, doing physical activity, and not smoking, eating fat-free foods.

Each child of recessive carrier parents has a 25% chance of acquiring ARPKD. ARPKD is also known as infantile PKD and presents as early as in the womb. This type of polycystic kidney disease is much more severe than the dominantly inherited disease due to the age of the patient, and the rapid rate in which it progresses. The disease can be fatal in the first months of life. Children making it past the newborn stage have a high survival rate, however, most will require dialysis or transplantation by age 10 (PKD Foundation). A diagnosis of ARPKD is detrimental to the child as well as their

The need for intervention in this disease is obvious, without it patient’s quality of life is greatly depleted. Finding a cure to completely prevent ADPKD at the moment is out of the question due to the complexity of the disease, and due to the amount of information we know being limited. But I think there is an opportunity in the cyst