1 - Describe the normal structure and functioning of cell membranes, and explain how they compare to the membranes relating to a specific abnormality in cystic fibrosis?
All cells have a cell membrane. The structure of membranes is formed from a double layer of phospholipids with proteins floating in it. The proteins are embedded on the surface and inside or bridge the double layers of phospholipids. This structure is called a mosaic model. The main function of cell membranes is to provide protection and support for the cell and they also control what enter and exit the cell to maintain internal balance, called homeostasis. There are two types of a membrane protein: integral proteins and peripheral proteins. The integral membrane proteins are
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The cystic fibrosis affects the exocrine gland, which are organs that secrete mucus. It normally produces thin, slippery secretions such as mucus, sweat, tears and digestive juice. The organs can be affected by cystic fibrosis are sweat glands, respiratory system, digestive system and reproductive system.
Sweat glands: The individual who suffers from cystic fibrosis, the amount of body salts lost in the sweat are higher than the normal people. This can cause problems during times of increased sweating. Such as hot weather.
Respiratory system: The lining of the respiratory tract which made of tiny, hair- like cells called the cilia. Their function is to keep the lung clean and clear from foreign substances and mucus. The person who suffers from cystic fibrosis, the cilia can not easily remove the thick and sticky mucus out of the air passages in the lung. The mucus clogs the air passages, causing a chronic cough and lung infections. Repeated of lung infections can lead to damage to the lung and leading to not get enough oxygen into the body.
Digestive system: The thick and sticky mucus blocks the pancreatic ducts and preventing the enzymes from reaching in the small intestine to digest food. The result is incomplete digestion and poor absorption of food
The respiratory system and digestive system work together by producing mucus, which is a part of the defense mechanism, the respiratory and the digestive system form. This is done by, the goblet cells when a microorganism enters the body. The main function of the mucus is to collect these micro organisms. The mucus then gets transferred down the oesophagus by cilia which then the mucus is exposed to hydrochloric acid that is in the stomach. The digestive system supports the respiratory system by making the necessary nutrients to the diaphragm, which enables breathing to take place effectively and efficiently without any problems.
Cystic fibrosis (or CF) is a disease of the secretory glands. To simplify the term, secretory comes from the word secrete; in this particular case we are referring to the production and secretion of sweat and mucus. Besides the fact that cystic fibrosis is an illness, it is
Cystic Fibrosis is a genetic disorder primarily affecting the pulmonary and digestive systems. It is also the most common fatal recessive genetic disorder among individuals of Caucasian descent. According to Garguilo, this disorder affects cells that produce mucus, digestive, and sweat juices. These mutated cells cause the fluids that are normally thin and slippery to become unusually thick and sticky, increasing the chance of blocking blood transport passageways, particularly in the digestive and respiratory systems that can then lead to recurrent infections. People with this condition have an abnormally high level of salt in their sweat and one of the factors leading to early diagnosis is the fact that parents can taste the salt on the skin
Cystic fibrosis, a genetic disorder, is currently affecting more than 30,000 people in the United States (About). According to “What is a Genetic Disorder?” (2014) “A genetic disorder is a disease that is caused by a change, or mutation, in an individual’s DNA sequence.” Cystic Fibrosis is an uncommon but serious disorder that causes consistent lung infections and limits the ability to breathe overtime. It affects the exocrine glands, which play a crucial role in regulating body temperature by producing sweat and many substances. It causes unusual heavy mucus, leading to blockage in the pancreatic ducts, intestines, bronchi, resulting in respiratory infection (About). Cystic fibrosis affects many people, and it has a specific mode of inheritance,
It affects mostly the lungs, pancreas, liver, intestines, sinuses, and sex organs. Also, it causes the mucus to be thick and sticky. The mucus clogs the lungs and the airways, causing breathing problems and bacterial infections in the lungs. The thick, sticky mucus can also clog tubes, or ducts, in the pancreas. These infections cause chronic coughing, wheezing, and inflammation. Over time, mucus buildup and infections result in permanent lung damage, including the formation of scar fibrosis and cysts in the lungs. As a result, the digestive enzymes that the pancreas makes cannot reach the small intestine. This can lead to repeated lung infections and lung damage. In people with cystic fibrosis, the body produces mucus that is abnormally thick and sticky. Cystic fibrosis, also causes a patient’s sweat to become very salty. Thus, when sweating, a patient loses large amounts of salt. This can upset the balance of minerals in a patient’s blood and cause many health problems. Examples of these problems include; dehydration, increased heart rate, tiredness, weakness, decreased blood pressure, heat stroke, and, even death. A common complication of Cystic fibrosis is diabetes. However, the type of diabetes associated with this disease often requires different treatment than other types of diabetes. Another common CF complication, which is the bone-thinning disorder osteoporosis which needs a treatment that
Cystic fibrosis is inherited when a child receives two recessive genes for the disease. It is a disease that affects the secretory glands. Secretory glands are the glands in a person’s body that produces mucus and sweat. Mucus is a very important factor in a person’s body. Mucus lines multiple organs and protects them from infection while also keeping them from becoming too dry. When a person has cystic fibrosis, their mucus becomes thick and can block certain air ways in their body.
Cystic fibrosis is an autosomal recessive condition of the secretory glands, which affects roughly 30,000 individuals in the United States alone (Cohen & Prince, 2012, p. 509). This chronic genetic disorder of the sweat and mucous glands affects a number of different anatomical structures including the epithelial cells of the respiratory tract, the exocrine pancreas, and the exocrine sweat glands. Cystic fibrosis results in the production of abnormally thick mucus which can detrimentally affect a number of different organs throughout the body, most notably the lungs and pancreas. With such a widespread effect on the body, cystic fibrosis is truly a multisystem disorder.
Cystic Fibrosis (CF) is an inherited disease of the secretory gland. Secretory glands that make mucus and sweat. People who have CF inherit two faulty genes one from each other parent the parents do not have the disease. CF affects the lungs, pancreas, liver, and sex organs. In CF, a defect (mutation) in a gene changes a protein that regulates the movement of salt in and out of the cells. The result is thick, sticky mucus in the respiratory, digestive and reproductive systems, and increased salt in sweat. Signs of CF vary, depending the severity of the disease. In the same person they might worsen or get better. The symptoms of CF is persistent cough (having mucus), wheezing, breathlessness, exercise intolerance, repeated lung infections, and
This disease affects multiple organs including the exocrine glands which secrete mucus. These glands normally produce thin slippery secretions including mucus, sweat, tears and digestive fluids. When a person has cystic fibrosis the mucus becomes thick and sticky. The parts of the body affected by cystic fibrosis are the sweat glands, respiratory system, digestive system and reproductive system. In patients with cystic fibrosis the amount of body salts (sodium and chloride) lost through sweating is increased. This situation can become more hazardous during exercise or hot weather. In a person with cystic fibrosis the cilia can’t move thick and sticky mucus easily. The mucus clogs the air passages and may cause a chronic cough and/or
Cystic fibrosis (CF) is a hereditary recessive genetic disorder of the secretory glands responsible for producing mucous and sweat. It is characterized by the disruption of epithelial cell function to produce a defective form of the protein cystic fibrosis transmembrane conductance regulator. When defective, epithelial cells cannot regulate the movement of chloride across the cell membrane, disrupting the essential balance of salt and water required to maintain a thin coating of fluid mucous(). Instead of acting as a lubricant, mucous becomes thick and sticky causing secretions to block tubes, ducts and passageways in the lungs and digestive system. Obstructions in the pancreas hinder the ability to digest and absorb fats and some nutrients
The membrane around the cells in the body is the boundary that keeps them from reaching the surroundings on the outside. It allows for certain substances to pass through to the cells rather than others, and it contains proteins and lipids such as phospholipids (cholesterol) (Erster 3). The simplest membranes are known as a phospholipid bilayer, given that there are two layers containing hydrophilic heads and hydrophobic tails allowing the membrane to have its semipermeability. The tails on both layers face the inside towards each other, while the heads are on the outside (Erster 4). They have a fluidity to it, being able to move from side to side, and rarely flip due to having to move through areas that are hydrophobic (afraid of water) and hydrophilic (attracted to water) since it would take a lot of energy to do so (Erster 10).
introduction: Cystic Fibrosis is a genetic condition that causes the internal organs (the lungs and digestive system) to become clogged with thick sticky mucus that results in chronic infections and inflammation of the lung.
Within this assignment, I will be looking at how materials are exchanged across the cells membrane. I will be explaining the processes, diffusion, osmosis, active transport and phagocytosis. My assignment will also explain how these exchanges are related to the cell membranes structure and, explain the movement of water from cells using the concept of water potential. Diffusion Diffusion is the process by which molecules spread from areas of high concentration, to areas of low concentration.
Throughout the past century, scientists have been able to conduct more research on the structure of a cell membrane and understand its components and functions. The present agreed on model, created in 1972 by S. J. Singer and G. Nicolson, is called the fluid mosaic model. This model depicts that proteins (integral and peripheral) form a mosaic since they are floating in a fluid layer of phospholipids, which makes up the components of the cell membrane (along with cholesterol). Each of these parts of the membrane enables it to be more efficient. The purpose of a cell membrane is to support and protect the cell, but also to control the movement of materials in and out of it. It
The cell membrane surrounds the cytoplasm of a cell and is the barrier as to what can and cannot pass through the cell. The cell membrane acts as a barrier and is one of the many key factors for supporting life, without it diffusion and osmosis would not be able to occur. The barrier is selectively/partially permeable and regulates what enters and exits the cell, therefore facilitating the transport of materials needed for survival. There is two processes in which substances are carried across the membrane, either passive transport or active transport. Passive transport transpires without the input of cellular energy albeit Active Transport requires cells to expend energy to move the substance across the barrier. The cell membrane also maintains cell potential.