Cellular Immune Response To The Bubonic Plague

Europe went through a period of calamities during the fourteenth and fifteenth centuries. Populations were wiped out and the church lost much of its power. The population of Europe faced two main crises during the early Renaissance period: the black plague and the Great Schism, and through their reactions, the Renaissance was allowed to flourish.

The Bubonic Plague killed over twenty-five million people during the Elizabethan Era (David Perlin, PhD and Ann Cohen). “The origins of the Black Death can be traced back to the Gobi Desert of Mongolia in the 1320’s (Ed. Geoffrey J. et al).” The Bubonic Plague has picked up many nicknames. For example, it has been called “The Black Death,” and “one of the four horsemen of the apocalypse” (Ed. Geoffrey J. et al). The Bubonic Plague was very prominent during its time with many people’s lives being affected by the treatments, preventions, and twisted theories that occurred.

75 to 200 million people died from the Bubonic Plague it was estimated about 2\3 of the European population died. Bubonic Plague hurts the Immune system by attacking an invading it. The only way to stop the Bubonic plague is by antibiotics and prescription drugs that destroy the virus. If not treated it will enter the bloodstream and attacks the lungs. Which could give the body Pneumonic plague which is deadly and the Pneumonic plague will give people hepatitis which will give the body fatigue and muscle weakness. The cells in the body system fights off bad pathogens. It keeps the body from getting infected with viruses and diseases like the flu. The Bubonic plague entered the Immune System by changing it form to disguise itself so it will let it in when it is in the Immune System. It attacks by shutting it down and kills cells inside. So the body cannot fight it off. Then it enters the bloodstream and without the immune system it cannot be stopped because the immune system fights off the virus. And without it fighting off viruses the body is prone to any diseases and viruses like the t cell which keeps the flu virus away from the body. And the Bubonic plague kills the t cell which now it is prone to the flu. And it also attacks the b cell which makes antibodies which helps the body become healthier and safer.

The plague was a catastrophic time in history, and happened more than once. It took millions and millions of people’s lives. It destroyed cities and countries, and many people suffered from it.

Made of a canvas outer garment coated in wax, as well as waxed leather pants, gloves, boots and hat. A dark leather hood and mask with a very grotesque curved beak (Jackie Rosenhek, 2011). A serial killer, Halloween costume perhaps or a cosplay outfit for a horror movie? No, a doctor actually is what this outfit was meant for. Doctors wore this attire in the medieval times in order to protect themselves from the bubonic plague. We 've all heard of the bubonic plague in our history classes. We know the numbers and effects and how deadly it was. However the bubonic plague is still on the hunt and loose. Yes, numbers in outbreaks of the bubonic plague have doubled since 2014. There have been very few, but a pathogen such as the Black Death is not to be taken lightly.

The Black Death, also known as the Bubonic plague, was a serious pandemic that killed more than one-third of Europe’s population. Between 1347-1352, the Black Death had “reportedly killed more than 20 million people.” The plague originated from Asia before traveling throughout Europe and the Mediterranean by fleas infested rats transported through ships. The infested ships had then landed in European ports such as the following: “Genoa, Venice, Messina, and other more.” Thus, the starting the pandemic by the spreading of the highly contagious bacterial infection disease around Europe along with their imports and exports.

The Bubonic plague has been said to be a part of history since the biblical eras and has had an undeniable effect on the development of contemporary civilization Gowen, B.S. (1907). The cause of the plague is not known. However, there is religious reference of God punishing sinners causing death and destruction using this deadly disease. Throughout the years, there has been a question to be answered by historians and medical professionals. This question is: if the destructive attributes of the disease was an act of God to punish sinners or an act of nature? Today, historians believe that the existence of germs, given suitable soil conditions, mass-produced the disease.

During the Black Plague, the responses from the Christian and Muslim society was different. Although they had similarities like they both thought that the plague was miasia carried by winds and one prevention method they both used was building fires to try and decontaminate the air. So, as the Christians saw this as a punishment from God because of their sins, the Muslim saw this as a divine act as it came from God himself.

A 1200 census stated that the Chinese population was close to120 million inhabitants. By 1393, their population dropped to around 62 million. Before long, the disease causing this drop in populace migrated into Europe. A diseased person would get a high fever, cold sweats, experience weakness, have migraines, and buboes (swollen, tender and painful lymph nodes) would appear. Without warning, buboes would spread to every lymph node in the body and blood would start to puddle under the skin. The skin then turned black and died. In its final stages, the victim had respiratory failure, went into shock, and died a slow, painful death. As described in this quote by Matteo Villani, “It was a plague that touched people of every condition,

The Bubonic Plague was likely the first semi-global pandemic that rightfully merits the name which means affecting all people. The period of time in which the disease wreaked havoc was also known as the “Black Death." Alexandere Yersin was a French bacteriologist and discovered the bacteria in Hong Kong This diabolical disease is characterized by both positive and negative outcomes for the few people that managed to survive the plague. The total number of people who died subsequently of the disease are not known. The total number of deaths ranged from twenty to fifty million people. Many, grotesque, unpleasant characteristics are associated with the Black plague. Scientists now understand that the Black Death was spread by a bacillus known as Yersina Pestis. The dominant carrier of the disease was the "black" rat. Other rodents located in central Asia could have also contributed to the disease spreading. A French biologist discovered the germ during the nineteenth century. Recently Dr. Jahannes Krause has been able to do some "molecular fishing" and extract the remaining plague fragments, and DNA from the tooth enamel of excavated remains from the 1300 's. There are three types of the infection. The manifest through buboes (boils) with unpleasant smelling odors, and spots on the skin. Swollen, inflamed lymph nodes in the armpits and groin would appear. The lymphatic system is a major contributing factor to one 's immune system and general health condition.

The bubonic plague was a devastating disease that rapidly swept across Europe. Also known as the Black Death, the plague spread from port to port and started to wipe out entire civilizations. All of Europe was eventually contaminated, with over two-thirds of the population dieing to the infectious disease. Believed to have started in 1346 when the Mongol armies overtook the Genoese trading outpost of Caffa on the Black Sea, over half the soldiers on the boat returned dead. The quickness of the infection and then death, brought a fear to these people they have never witnessed before. The sudden death caused by the disease created a paranoria among the people that Armageden had arrived.

The Black Death was one of the most shocking epidemics in human history. Caused by a single flea weighing 1.08 mg, carrying Yersinia pestis, a bacterium that would is responsible for the plague (Lee, 2017). The bubonic plague of 1347-1350, killed up to 1/3 of the population throughout Europe and turned its social structure into a tailspin.

People with poor immune systems, such as Mr Wilde, are at risk of a severe infection by the cytomegalovirus (Torpy, 2010). Mr Wilde is immunocompromised due to his HIV, a virus that weakens the immune system and compromises its ability to fight infection (Gillespie, 2014). HIV affects CD4+ T lymphocytes, which normally fight infection, killing the cells until they can no longer fight infections that would not infect someone with a healthy immune system (Craft and Gordon, 2010). The virus replicates in the first few weeks, and is accompanied with flu-like symptoms (Craft and Gordon, 2010). Infected patients are then generally asymptomatic for years, until their CD4+ T lymphocytes are so low in number that they become debilitated by normally harmless infections; although treatment can slow the disease, it is ultimately fatal (Craft and Gordon, 2010). Human immunodeficiency virus

The idea that knowledge varies between accuracy and simplicity is, to me, incorrect. Accuracy of knowledge more nearly means valid or correct information but the statement implies that accurate information strictly correlates with complexity in understanding. Therefore, if something is simple or basic in its understanding and production, it is not accurate. Most areas of knowledge depend on accurate information that can be proven and justified, however, are either so ever-changing that accuracy and simplicity seem out of reach, or they are so objective that the complexity of the knowledge is solely dependent on its interpreter. I will examine the development of knowledge in the arts and its interpretation as well as examining the natural

HIV is global pandemic stands for Human Immunodeficiency Virus, weakens the immune system by destroying the important cells in our body that fights against disease and infection. Our immune system is able to clear out most of the viruses from our body, but once you have HIV , you have it for lifelong. HIV can hide in our body cells for long time and it can attack the T cells and CD4 cells, a key part of our immune system to fight infections and diseases. Overtime, the HIV may attack so many of CD4 cells and our body is no more able to fight against infections. When this happens, HIV can lead to AIDS, the final stage of HIV infection. HIV can be transmitted through sexual contact, injection or drug use, pregnancy, breast feeding, occupational exposure, and rarely through blood transfusion and organ