Central Neurocytoma Paper

A person has a 0.55–0.7% chance of developing any type of brain tumor in their lifetime (Mohammadi and Schroeder 1). A brain tumor is a mass of abnormal cells located somewhere in the brain. Brain tumors can be caused by many different disorders including Tuberous Sclerosis Complex (TSC). Some tumors caused by this disorder are inoperable. Inoperable brain tumors can now be treated using new advanced technology. Technological advances provide new hope for patients who have inoperable brain tumors and TSC.

The primary ones include these types. Gliomas, the most common brain tumor involving the brain tissue. There are different grades and even types of gliomas. But if the tumor grade is higher, it will probably grow faster. Medullblastomas are brain tumors that in young children. Without treatment it will spread rapidly into the spinal fluid and other parts of the brain. But almost or half of the brain tumors found are benign. These types of brain tumors are usually Meningiomas and Neuromas. Meningiomas begin in the tissue membranes. Neuromas are in the nerves mostly in people over

Tumors can be classified into three types: 1) benign 2) pre malignant 3) malignant tumor. Benign tumors are those which are incapable of abrupt expanding and affecting the other healthy brain tissues. Premalignant tumor is a pre cancerous stage, if not treated properly it may lead to cancers. It is often considered as a disease. Malignant tumor grows rapidly with time an ultimately leads to death of patient. Malignant is a medical term describing a sever growth of a disease. The most common primary brain Tumors are gliomas, wherein 70% are in the group of malignant gliomas, glioblastoma multiform (GBM).The GBM is one of the highest malignant human

Glioma is a tumor that is a type of brain cancer. Glioma tumors are made up by cells called glial cells. Glial cells normally provide nutrition, oxygen, and structural support to the brain. Three types of glial cells can produce tumors. Gliomas are named after the type of glial cell that is involved in the tumor. A tumor is formed when the glial cells grow into an abnormal mass of tissue. Gliomas are one of the most common types of brain tumors that occur in adults.

An Intracranial tumor is an irregular group of brain tissue in which cells widen and cultivate intractably, which effects the means to control normal cells. Intracranial tumors situated in the frontal lobe are quite natural since this lobe is the biggest in the brain. These growths are categorized as primary, which means they start out in the brain (benign), or secondary, meaning they have a different starting location in the body and spread to the brain (metastasized). Primary tumors tend

The name of a brain tumor derives from the cells where it forms. Ependymoma starts in the ependymal cells. The ependymal cells line the ventricles in the brain and central canal of the spinal cord (ABTA, n.d.). These two areas, the brain and the spine, make up the central nervous system that controls many significant functions like speech, thought, and physical movement. Ependymoma is in a category of brain tumors called gliomas. A glioma grows from glial cells, a supportive cell found in the brain (ASCO, n.d.).

The diseases associated with FUBP1 include oligodendrogliomas, astrocytomas, and oligoastrocytomas. Oligodendrogliomas are primary glial brain tumors and can be either low-grade (grade II) or high-grade (grade III). [2] Since oligodendrogliomas have a slow growth rate, they are often present for years before they are diagnosed. Nevertheless, the most common symptoms include: seizures, headaches, and personality changes. Altogether, the symptoms vary by location and size of the tumor. About 66 to 78 % of people with grade II oligodendroglioma survive for about 5 years after diagnoses, while 30 to 38 % of people with grade III will survive for about 5 years after they are diagnosed. [3] Astrocytoma is another type of brain cancer that stats in the cerebrum, which is the largest part of the brain, but can also appear in the cerebellum, which is the back of the brain. It is more common in men than in women. Like oligodendrogliomas, the most common symptoms of astrocytomas include: headaches, seizure, changes in behavior and memory loss. [4] Prognosis of astrocytomas depends on the type of astrocytoma. Altogether, a low-grade astrocytoma (LGA) has an 83 % 10-year overall survival, while the overall survival rate of a high-grade astrocytoma (HGA) range between 15-20%. In both oligodendrogliomas and astrocytomas, the FUBP1 locus is mutated which leads to the inactivation of

An Astrocytoma is a type of tumor that is created by star-shaped cells called astrocytes. These astrocytes are the largest and most numerous type of neuroglia in the Central Nervous System, and make up the supportive tissue of the brain. Because of the size and number of astrocytes they are the most common Central Nervous System tumor. Although Astrocytomas are so common, the cause remains unknown. Researchers believe that genetics could be a part of the cause of Astrocytomas. Astrocytes combine with other support cells called Oligodendrocytes and Ependymal cells to make up glial tissue. Tumors within the glial tissue are referred to as gliomas. This means that an Astrocytoma is a glioma tumor, and can be broken down into four grades or levels based off of how aggressive the tumor is.

"You never know how strong you are until being strong is the only choice you have." Battling any kind of Cancer is rough. One of the most common cancer there are is a brain tumor. Brain tumors can change a persons life upside down because you have to battle something that inside of your own body.

Neuroblastoma (NB) is the most common extra-cranial solid tumor in children under 5 years age and arises from the embryonic neural crest .1It accounts for 8–10% of child- hood cancers and accounts for 15% of the deaths from cancer in the pediatric age group.2NB display extreme heterogeneity ranging from spontaneous regression to malignant progression3.NB Is stratified into three risk categories: low, intermediate, and high risk. Low-risk disease is most common in infants and good outcomes are common with observation only or surgery, whereas high-risk disease is difficult to treat successfully even with the most

The classic ES appears like that of a primitive, undifferentiated neoplasm morphologically. Histologically, there are small round blue cells in the form of monotonous sheets with hyperchromatic nuclei and scant cytoplasm (8). All the 24 cases in this review satiate these histologic criteria (Table 1). The tumor consists of extensive necrotic areas but viable tumor is usually preserved around blood vessels. Some tumor cells can also invade blood vessels. Some features are absent typically like nuclear atypia, palisading, and formation of rosettes (where the tumor cells are arranged in a circle about a central fibrillary space, indicative of neural differentiation or pseudo rosettes. The markers like P30/32MlC2 and at least two kinds of neuronal markers are the immunohistochemical criteria for the diagnosis of PNET. (12) Monoclonal antibodies like CD99, O13, HBA71, 12E7, RFB1 are also tested although none of them are actually specific for PNETs. (12) The neural markers like Neuron Specific Enolase(NSE), Chromogranin A(CgA), Synaptophysin(Syn) are usually positive but markers such as desmin, actin, S-100, insulin, glucagons, somatostatin are rarely

The United Kingdom has 9,400 cases of primary brain tumors. Four hundred of those cases consist of children under the age of 15, and 300 cases consist of teens and young adults between the ages of 15 and 24. (2 “Brain” 4) In 2001, doctors diagnosed 35,519 people with a primary malignant or benign brain tumor (Wrensch 278). Brain tumors are the second most common killer in children under 15 and forth most common in teens and young adults between 15 and 24 (2 “Brain” 3). Children with brain tumors account for seven percent of the patients with these kinds of tumors. Thirty percent of brain tumors are glioma. Malignant brain tumors kill 13,000 Americans per year. (Bradley

Cancer of the central nervous system – Originates in the tissues of the brain and spinal

Common malignant brain cancers increase significantly according to statistical data collected by the National Cancer Institute. In 1984, the annual incidence rates of primary brain tumor and primary brain lymphoma also increased notably, the rate of lymphoma almost tripling,

As stated by President John F. Kennedy, “Efforts and courage are not enough without purpose and direction.” my efforts to complete this search would be meaningless without a direction. First, I decided it was best to understand the strength of the disease I was up against. To better understand, I searched online and I found Funk & Wagnalls New World Encyclopedia, for my understanding of the basic epidemiology of brain tumors. According to Funk & Wagnalls New World Encyclopedia, there are two types of brain tumors,“Benign brain tumors tend to grow relatively slowly and to remain confined to one location” and “Malignant brain tumors tend to grow more quickly and spread within the brain or spinal cord”(“Brain Tumor”). Malignant brain tumors have become my focus because the Benign tumors are not cancerous. Now that I have found my focus, I would like to search for risk factors.