Cervical Cancer Essay

Throughout the world, HPV is also very prevalent. Cervical cancer from HPV is the second most common cancer in women living in underdeveloped countries (WHO, 2016). Many of these underdeveloped and lower income countries do have access now to the common forms of the HPV vaccine. In 2008, more than 500,000 new cases of HPV were reported worldwide (WHO, 2016). The prevalence of cases throughout the world is about 79 million reported cases (WHO, 2016).

Cervical cancer is when there are malignant cells present in the cervix; it is developed in the lining of the cervix. A cervix is a narrow opening located at the bottom of the uterus that leads into the vagina. Cervical cancer mostly affects women between the ages of 40 and 55. This cancer can be prevented by screening for precancerous cells, and it can also be cured if it is detected at an early stage. Over the past few decades the number of cervical cancer cases has declined dramatically due to a more widespread screening of the disease. Today, it is estimated that 10,000 new

Cervical Cancer affects around 34000 women every year around the UK (Bupa UK, 2013). Cervical Cancer is a result of the mutation of the DNA caused by the by the Human papillomavirus (HPV), (NHS, 2013).

There are upwards of forty types of HPV. Along with the genital areas HPV can infect the mouth and throat. HPV can cause genital warts and cancer. It can sometimes go away by itself and people who have it can be asymptomatic. HPV can be passes through genital contact, vaginal sex, anal sex and even oral sex. This can be passed both heterosexually and homosexually. Rarely, pregnant women can pass HPV on to her baby during delivery. According to the CDC 79 million Americans now have HPV and 14 million new cases are found each year. It has become so common that nearly all sexually active people will have at least one type of HPV in a lifetime. 10,300 women per year are diagnosed as having cervical cancer. HPV can be prevented by condom use and having safe monogamous sex

According to the Centers for Disease Control and Prevention (CDC), Human papillomavirus (HPV) infects roughly 20 million individuals in the United States with 6.1 million new cases each year. There is no cure for HPV, only treatment for associated health problems. There are more than 30 strains of HPV that affect more than half of sexually active individuals in their lifetime. Public health risks involve several types of HPV leading to precancerous lesions and causing 70% of cervical cancer. Cervical cancer, the second most common cancer, affects many women globally. In the United States, nearly 10,000 women are diagnosed with cervical cancer annually and 3,700 of those women die. It has been reported by American Cancer Society that with early

Cervical cancer is the leading cause of cancerous death, in women, since 1950. Approximately 200,000 cervical cancer patients die each year in developing countries. Strains like HPV 16 and 18 cause about 70% of cervical cancer in women– one of the top causes of death in the world (WebMD, 2010, p.1). In the Unites States, about 10,000 women acquire the disease and 3,700 die annually Human Papilloma Virus (HPV) is directly associated as a cause of cervical cancer. This virus affects the skin and genital area and, in some cases, it can also infect the throat and mouth. Since the HPV is passed from one person to another through skin-to-skin or sexual contact, sexually active people are more prone to this virus. Merck

HPV is the single biggest cause of cervical cancer and oropharyngeal cancers, according to the CDC. Between 2008 and 2012, almost 39,000 U.S. citizens were diagnosed with HPV-related cancer every year. Fifty-nine percent of them women and 41 percent men, researchers report. But while Pap smears and HPV tests have reduced rates of cervical cancer in woman, rates of oral cancer are growing in men.

In US cervical cancer is ranked 13th most common cancer in women and 4th among women between 15 to 44 years.

In their 2015 study Alves Ribeiro et al. found that women who began having sexual intercourse prior to age of 16 were more than four times as likely to have a HPV infection (OR 4.41; 95%CI:1.20-19.33), and nearly five times as likely for that infection to involve serotypes 16 and 18 (OR 4.68; 95% CI: 1.20-21.32). Moreover, women with a sexual debut prior to age 16 were twice as likely to have a diagnosis of cervical intraepithelial neoplasia (CIN)1 or greater (OR 2.2; 95% CI: 0.94-5.08 CITE 2. The same study also demonstrated a statistically significant association between CIN 1 and HPV infection, especially infection with HPV serotypes 16 and 18 (OR 2.76; 95% CI: 1.05-7.19) and (OR 3.53; 95% CI: 1.17-10.67) respectively (Alves Riberio et al., 2015). Over 90% of females in the United States are sexually active by age 24; correspondingly, the prevalence of high-risk HPV peaks at over 43% in the 20-24 age group (Vegunta, Kransdorf, & Mayer, 2014). By age 30, the prevalence of high-risk HPV decreases to 30.4%, and continues to decrease as age increases. It is thought that this age related decrease in prevalence can be attributed to a combination of factors, including, decreased exposure, resistance to reinfections, and HPV’s self-limiting nature (Alves Ribeiro et al., 2015; Vegunta et al., 2014).

Did you know there is more of a link between cervical cancer and HPV than smoking and lung cancer? Cervical cancer is currently the fourth most common cancer in women and the second leading cause of death from cancer in women. Along with those statistics, human papillomavirus is the most common sexually transmitted viral disease amongst men and women worldwide. The prevalence of women having a strain of HPV that ultimately leads to or increases the chance of cervical cancer is highly relatable. What is pathophysiology, signs, symptoms, prevention, and treatments of this ailment? You might ask will be covered in the next few pages of this paper.

Human Papillomavirus (HPV) is a sexually transmitted virus that spreads from person to person by direct contact of infected tissue. According to the CDC, nearly all men and women will contract HPV at some point in their life (Centers for Disease Control and Prevention [CDC], 2013). HPV can cause cervical, vaginal and vulvar cancers in females. HPV can also cause anal, throat, and neck cancer in both males and females. HPV is also known to cause genital warts in both males and females. According to the National Cancer Institute (2013), “approximately 12,340 new cases of cervical cancer will be diagnosed in the US, and 4,030 US women will die

Cervical cancer is a typically slow-growing type of gynecologic carcinogenesis caused predominantly by persistent infection with the human papillomavirus (HPV), most commonly the high-risk genotypes HPV-16 and HPV-18.3 Cervical cancer typically originates in the transformation zone of the cervix, where there is a junction of ectocervix and endocervix. The most common type of cervical carcinoma is squamous cell carcinoma and makes up 70-80% of cervical cancers. This type of cervical cancer occurs in the squamous cells of the ectocervix. The second most common type is an adenocarcinoma, occurring in glandular cells of the endocervix, and makes up 10-15% of cervical cancers. Cervical cancers can also be a mixture of dysplastic squamous cells and glandular cells; this type of carcinoma is termed adenosquamous carcinoma and makes up 1-2% of cervical cancers. The final type of cervical cancer is associated with HPV-6 rather than HPV-16 or HPV-18. It is termed verrucous squamous carcinoma and is very rare.5, 6

The fourth most common cancer in women worldwide happens to be Cervical Cancer. It also has the fourth highest mortality rate among cancers in women.

About 12,820 new cases of invasive cervical cancer will be diagnosed in America every year (5). This is out of the 1,685,210 people diagnosed with cancer every year. About 39.6% of the US population will contract cancer in their lifetime (10). With so many people affected by cancer, it is beneficial to understand how cancer works. However, cancer is a very complex disease that scientists are still trying to understand themselves. Moreover, cancer can be a very frightening disease because of its difficulty to treat, and its lethality. Understanding the pathology and history of cancer can be beneficial to help understand the inevitable cancer diagnosis of yourself or a loved one.

Although there are several known risk factors for getting cervical cancer, no one knows exactly why one woman gets it and another doesn't. One of the most important risk factors for cervical cancer is infection with a virus called HPV (human papillomavirus). HPV is a sexually transmitted disease that is incredibly common in the population, one study showed that 43% of college age women were infected in a 3-year period. HPV is the virus that causes genital warts, but having genital warts doesn't necessarily mean you are going to get cervical cancer. There are different subtypes, or strains, of HPV. Only certain subtypes are likely to cause cervical cancer, and the subtypes that cause warts are unlikely to cause a cancer. Often, infection with HPV causes no symptoms at all, until a woman develops a pre-cancerous lesion mostly of the cervix. Because infection with a STD is a risk factor for cervical cancer, any risk factors for developing STD are also risk factors for developing cervical cancer. Women who have had many or several male sexual partners, having sexual intercourse at an early age, or have had male sexual partners who are considered high risk (meaning that they have had several sexual partners and/or began having sexual intercourse at an early age) are at higher risks for developing Cervical