Chemo-Radiation Therapy Case

Mayo Clinic PRT (Moertel, Lancet 1969; PMID: 4186452) randomized 64 patients with locally advanced unresectable pancreatic ACA to RT alone vs. chemoRT (35 to 40 Gy +/- concurrent 5-FU). Survival was significantly improved with chemoRT (10.4 vs. 6.3 months). A subsequent Gastrointestinal Tumor Study Group Trial 9273 also demonstrated benefit with chemoRT (Moertel, Cancer 1981; PMID: 7284971). Patients (194) were randomized to RT alone (60 Gy) vs. chemoRT to 40 Gy vs. chemoRT to 60 Gy. RT was given as a split course with 2 weeks between each 20 Gy. Chemo was 5-FU 500 mg/m2/d on d1-3 of each 20 Gy course and then maintenance 5-FU for 2 years. Concurrent chemoRT improved MS compared to RT alone, and there was a trend toward better survival

cancer cells, either by killing the cells or by stopping them from dividing. Radiation therapy is a treatment that uses high-energy x-rays or other types of radiation to kill cancer cells or keep them from growing. Immunotherapy is a treatment that uses the patient’s immune system to fight cancer. Lastly targeted therapy, is the treatment that uses drugs and other substances to attack cancer cells. Some of these treatments are standard and others are being clinically tested in clinical trials. Patients may enter clinical trials before, during, or after starting their cancer treatment. Follow-up tests may be needed.

The aim of the treatment is to remove the tumor without damaging the tissues around the tumor.Treatment may include liver resection, radiation and medication.The treatment for malignant tumor is liver resection,chemotherapy

Most chemotherapy drugs are given as a course of up to ten sessions (cycles) of treatment. This will depend on the type of drug you are having. At each treatment session you will be given the chemotherapy drug through a drip (infusion). This involves running a liquid containing the drug through a fine tube (cannula) into a vein in your arm. This allows the drug to enter the bloodstream and travel throughout the body.

Reynolds, R. B., & Folloder, J. (2014). Clinical Management of Pancreatic Cancer. Journal of the Advanced Practitioner in Oncology, 5(5), 356–364. Retrieved July 9, 2017, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457174/

• Surgery to remove as much of the cancer as possible. Sometimes the whole liver is removed and replaced with a healthy liver (liver transplant).

A lot of thought and soul-searching went into my decision to further my education and pursue my master’s degree. Having waited until after I started my family to really go after my educational goals involved a lot sacrifice. Completing 6 years of schooling to obtain the profession I am in; while also being a military spouse and mother of three took dedication, motivation, and perseverance. Throughout my time obtaining my education in the field of Radiation Therapy, I developed an appreciation and passion for learning as well as teaching. Realizing that I could bridge my love of healthcare with my passion for education inspired me to set a goal for myself, that I am now trying to achieve.

The Radiotherapy department has invited an independent team to investigate two separate incidents, reported by a Consultant Oncologist, in a radiotherapy department. This is required under the guidance of the Ionising Radiation (Medical Exposure) Regulations in Radiotherapy (IR(ME)R) as a human error has led to an exposure much greater than intended to a specific individual (Royal College of Radiologists 2000).  Previous incidents if enough words left

Cancer is the main cause of growing mortality all over the world , it is expected that there will be 19.3 million new cancer cases yearly projected for 2025 [1]. Yearly over a million cases of death worldwide is due to breast cancer [2]. Both environmental and genetic factors play an important role in cancer susceptibility [3, 4]. The cumulative effects of individual (non-carcinogenic) chemicals acting on different pathways could produce carcinogenic synergies [5]. Current treatments for cancer include surgery, hormonal therapy, radiotherapy and targeted therapies. Molecular target therapies have a great role in the treatment of cancer, they include inhibitors of the tyrosine kinase enzyme BCR-ABL, inhibitors of vascular endothelial growth factor receptor (VEGFR) and epidermal growth factor receptor (EGFR) inhibitors

A 45 year old male, with a history of smoking ½ packs of cigarettes a day for the past 30 years has been diagnosed with laryngeal cancer. The patient comes into the hospital for a follow up visit to his health care provider. Where he has been getting radiation and chemotherapy treatments for the cancer. He has complaints of pain, dyspnea at times and dysphasia. While discussing the progress of his condition the doctor states that the chemo and radiation therapy has not been successful and the cancer has started to progress. The doctor then states the next steps to prevent the spread of the cancer, and that’s to have total laryngectomy surgery. The patient understands the severity of his condition but is now experiencing anxiety because of

One of the vital components of a radiation therapy position is the ability to work as a valued team member. I spent two months in a clinic that lacked a strong team dynamic. I believe this started with the lead therapist who was disconnected from the team and it felt as though the team was constantly fighting against each other. This lack of leadership and team dynamic was taking a tool on the work flow on the department but most of all it was affecting the patients. When I was there I could tell that some of the patients were affected by the lack of communication. Being new in this field and the department I found it difficult to witness this and not say anything.

One other major form of treatment would be radiation therapy. The method “zaps” the cancer from the body by focusing on the infected area. It damages the existing cancer cells and discourages new cells from growing. The method of treatment can be given to a patient externally exposing the affected area with high levels of radiations. There are also implants that can be placed under the skin that

BRAF fusions, kinase activation is the resultant effect. Due to their size and location, pLGG biopsies are generally

INTRODUCTION Pancreatic cancer is the fourth leading cause of cancer death Worldwide. It is the eighth most common cause of death from cancer in both individuals. Higher incidence is noted as thirteen because of the very poor prognosis. Less than 5% of all patients are still alive only for 5 years after initial diagnosis. It is rarely detected in the early stages and conventional cancer treatment failed due to high resistance to chemotherapy.

The numbers of people who are dying due to crucial diseases such as cancer have