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Chlorofluorocarbon Pros And Cons

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Chlorofluorocarbon (CFC)-containing inhalers, or CFC propellants, were commonly used in US inhalers prescribed to treat asthma and COPD (Hendeles, Colice, & Meyer, 2007, p. 1344). However, CFC is an organic compound that accumulates in the stratosphere (Hendeles, Colice, & Meyer, 2007, p. 1344). CFC causes deleterious effects on the atmosphere and thus reduces the protective effects the stratosphere has in minimizing ultraviolet B radiation (Hendeles, Colice, & Meyer, 2007, p. 1344). “The World Health Organization estimated that a 10% decrease in stratospheric ozone levels would lead to an additional 300,000 non-melanomas and 4500 melanoma skin cancers worldwide annually” (Hendeles, Colice, & Meyer, 2007, p. 1344).
The 2008 ban stems from
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1345). Higher levels of albuterol may be detected, when comparing blood work in individuals who have had large doses of albuterol using an HFA inhaler compared to in individual who had received large doses using a CFC inhaler (Hendeles, Colice, & Meyer, 2007, p. 1346). Also, some HFA inhalers can be made without the use of other substances (Hendeles, Colice, & Meyer, 2007, p. 1347). For example, Ventolin HFA is made with just albuterol sulfate and HFA (Hendeles, Colice, & Meyer, 2007, p. 1347). The lack of ingredients allows for better tolerability by patients (Hendeles, Colice, & Meyer, 2007, p. 1347). Also, excess doses in the devices have more consistent drug doses in HFA inhalers than the CFC inhalers (Hendeles, Colice, & Meyer, 2007, p.…show more content…
1350). Generic medications tend to be cheaper (Hendeles, Colice, & Meyer, 2007, p. 1350). Patients also report that the HFA inhaler tastes and the spray feel different, “softer” (FDA, 2016). The spray itself is different in the two types of inhalers (Hendeles, Colice, & Meyer, 2007, p. 1346). HFA inhalers require routine cleaning and priming to function properly (FDA, 2016). Ventolin HFA attracts moisture and drying agents are used in the product to counteract this (Hendeles, Colice, & Meyer, 2007, p. 1347). The use of drying agents decrease the shelf life after it is removed from its packaging (Hendeles, Colice, & Meyer, 2007, p. 1347). And, lastly, higher doses of HFA cause more systemic effects including tachycardia and hypokalemia (Hendeles, Colice, & Meyer, 2007, p.
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