Chromosome 10 Research Paper

The direct cause of this disease is unknown although several theories do exist; immune system problems, genetics or environmental factors. Most experts believe that genetics and intestinal bacteria are the developing factors of the disease. Theoretically, the adaptive immune system of an otherwise healthy individual will try to compensate for a deficient innate immune system creating white blood cells to destroy helpful microbes which inadvertently tear down the lining of the intestines causing ulcers, scar tissue and narrowing of the lumen within the intestine causing blockage. ( meded, 2010) Genetically, research has found a gene, NOD2, which produces a mutation and is linked to autoimmune diseases like Crohn’s.

1. List whether the student was positive or negative for each characteristic and include whether the characteristic is dominant or recessive. (6 points)

There is approximately a fifteen to twenty five percent chance of Inflammatory Bowel Disease in the extended family of someone who has Crohn 's. However in this situation, ulcerative colitis would be less likely than Crohn 's. The risk of Inflammatory Bowel Disease occurring if both of a child 's parents having an IBD begins at least around fifty percent. According to Mayoclinic.org, open quote "As many as 1 in 5 people with Crohn 's disease has a family member with the disease" closed quote. Crohn 's Disease is most commonly found in advanced areas like in Scandinavia, North America, the United Kingdom and Western Europe. Crohn 's Disease affects Ashkenazi Jews and Caucasians more than any other racial groups. Another reason that supports the theory of genetics being a cause of Crohn 's can also be found on page eleven in the same book as the book in the first reason. On page eleven it is written: open quote "While little has been accomplished so far in ulcerative colitis, mutations in a gene known as NOD2, located on chromosome 16, have been shown to predispose some people to Crohn 's in the Ileum, especially the form of the disease that causes a lot of scarring and narrowing" closed quote. In other words, there has been mutations in a gene found on chromosome sixteen that have been proved to cause some people to get Crohn 's in the Ileum (which

Lauren Page is 28 years old. She was diagnosed with Crohn’s disease when she was 24 going on 25 years old and was hospitalized during her birthday week. Her breaking point was when she could not take the pain any longer. Lauren had a fever of 104.5 and unbearable abdomen pain. She had also contracted an infection in her bloodstream from developing a fistula from her vagina to her rectum. Luckily they were able to do surgery to correct her fistula. She had a multitude of tests including: blood work, stool samples, CT scans, MRI, X-rays, a balloon test, endoscopy and countless colonoscopies. Lauren’s disease is located in her large intestines. Chron’s disease is not apart of Lauren’s family so she was clueless to what it was when she was diagnosed. It took about a month until they were completely certain that it was Crohn’s disease. Her iron was low and she was borderline anemic, had massive weight loss, and chronic pain in her abdomen. She

Lauren Page is 28 years old. She was diagnosed with Crohn’s disease when she was 24 going on 25 years old and was hospitalized during her birthday week. Her breaking point was when she could not take the pain any longer. Lauren had a fever of 104.5 and unbearable abdomen pain. She had also contracted an infection in her bloodstream from developing a fistula from her vagina to her rectum. They luckily were able to do surgery to correct her fistula. She had a multitude of tests including: blood work, stool samples, CT scans, MRI, X-rays, a balloon test, endoscopy and countless colonoscopies. Lauren’s disease is located in her large intestines. Chron’s disease is not apart of Lauren’s family so she was clueless to what it was when she was diagnosed. It took about a month until they were completely certain that it was Crohn’s disease.

Crohn's Disease is a rare, chronic disorder that is classified as a form of IBD (Inflammatory Bowel Disease). Although it's cause isn't completely clear, recent research has shown that it may be influenced by variations in certain genes, as well as chromosomes number 5 and number 10. There are many other influences, however, on the cause of Crohn's Disease. This disease often results in a wide range of symptoms. The diagnosis of Crohn's is determined through various tests. Unfortunately, there is no known cure for Crohn's, only different forms of treatment. Research and tests are still

Crohn’s disease is a chronic inflammatory bowel disease (IBD) that does not have a cure. This disease causes inflammation anywhere along the digestive tract, sometimes in several places at once. This disease equally affects both males and females and can be passed through family genes. The disease usually appears in teenagers and young adults. The inflammation in Crohn’s disease involves all of the intestinal wall and follows two main patterns; the disease may cause stricture to affected areas, eventually causing blockages, or it may cause formation of abnormal passageways between affected areas and nearby structures (fistulation). Symptoms fluctuate, but may include abdominal pain, severe diarrhea (often with blood), loss of appetite and weight,

Researchers have yet to find the definite cause of colitis, but they do know that key factors play a role, such as, “Between 10 – 20% of people with ulcerative colitis have family members with the disease” (University of Maryland 1). Researchers believe that if a first degree relative has the disease you are more likely to inherit it rather than someone with no relatives who have colitis. Genetic studies are so far inconclusive, as “Research studies have shown that certain abnormal genes may appear in people with ulcerative colitis. However, researchers have not been able to show a clear link between the abnormal genes and ulcerative colitis” (NIH 2). In order to know for a fact that genes play a role in having colitis more research would need to be done. It is also more common to be diagnosed between the ages of 15 and 35 (University of Maryland 1). Another factor that could play a role in the cause of colitis is an overactive intestinal immune

The Chimera of Arezzo (first half of the fourth century., Bronze) was made by the Etruscans. It was found in Arezzo in 1553. It is believed to be part of group of bronze statues depicting a battle. The Chimera is a part of Greek mythology. A monster believed to breathe fire. Its defeat to the hero Bellerophon was a legend, which is why it is portrayed as a battle locked creature bleeding and ready to attack. This sculpture was created as an offering to a god believed to be commissioned by a wealthy Etruscan. It shows how the Etruscans used many different influences from different cultures and made them their own.

What would you do if you found out that your child has Trisomy 13 Syndrome? Trisomy 13 syndrome is a disorder in the chromosomes by which having three copies of chromosome 13 in a cell for the body instead of having two copies having three. The major causes of trisomy 13 is because of a trans-located chromosome to another chromosome 20%of this case is caused by trans-located chromosomes. The symptoms of the disorder are a cleft palate, cleft lip, heart defects, brain and spinal cord abnormalities, failure to growth and weight also feeding difficulties, and seizes along with having set eyes.

Some researches believe the XYY chromosome is to be considered the “criminal” Chromosome. R. G. Fox suggests a longitudinal study be done to verify this because the information that is currently provided is not enough to confirm whether or not the XYY chromosome could be linked to aggression, below-average intelligence, or Antisocialism.

Will your child be the 1 out of 2500 births with Trisomy 18? Trisomy 18 is caused by an error in cell division while in embryonic development. It is caused by an extra chromosome on chromosome 18. (So, there is three chromosome 18 instead of the regular two.) Usual symptoms are low weight at birth, small abnormally shaped head, and organ defects that are often fatal.

Introduction: Mr. A (pseudonyms) is a 39 years old male of Indian origin. He is married and lives with his wife and a five years child. He is full time self-employed individual with no known health issues. Mr. A initially experienced constipation, blood in stool and abdominal pain which prompted Mr. A to visit his general practitioner (GP). Then he was referred to specialist and went through a series of medical examinations, blood tests, imaging procedures, and hospital admissions that were required to eliminate the other possible causes and diseases related to these symptoms. It was awkward and unpleasant to deal with the symptoms for him. He felt weak and started to lose weight. Eventually, Mr. A was diagnosed with crohn’s disease (CD) a type of inflammatory bowel disease (IBD) in 2012. IBD is a collective group of disorders that are chronic and incurable and characterised by inflammation in the intestinal tract. (Chang & Johnson, 2014, p.446). Crohn’s disease (CD) and ulcerative colitis (UC) are autoimmune diseases, where the body attacks the digestive system. Crohn’s disease can occur in any part of the intestine and ulcerative colitis only affects the large intestine (Ministry of Health, 2015). Although the individual susceptibility to develop inflammatory bowel disease (IBD) appears to be genetically determined, the actual occurrence of the disease is largely influenced by environmental factors (Lichtenstein & Scherl, 2011, p.77).This has been a life changing

This is a possible diagnosis for our patient. The mean age of diagnosis for IBD is 12.5 and our patient fit into that age group. The patient is also of Jewish heritage, which has an increase prevalence of IBD. Furthermore, the patient presents with abdominal pain, low weight, and occult blood in stool that can be found with CD and UC. Our patient does not have a family history of IBD even though 25% of children with IBD do, but that does not rule out the diagnosis. Furthermore, our patient does not have many of the extra-GI features of IBD, which include arthralgias and rashes, making this diagnosis less likely. Finally, an endoscopy was done and no cobblestoning features or pseudopolyps were seen. Thus, IBD is a possible

The Human Genome Project basically was a research program that worked on a goal to get an image of human genome and get a better understanding of all a human beings genes. DNA is founded on 4 chemical bases, they turn into twisted ladder shaped DNA molecules. And all the the four bases are what create the genes just placed in different ways and different lengths. One revelation of the human genome project was when they learned that there are about 20,500 genes. The Human Genome Project brought many scientist together around the world and each one was an important factor for the project. It was a publicly funded organization and got funds and support from the Department of Energy and US National Institutes of Health