Chronic Condition Of Unknown Etiology

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“Fibromyalgia is a chronic condition of unknown etiology characterized by widespread pain, persistent fatigue, nonrestorative sleep and generalized morning stiffness.” “The word “fibromyalgia” is derived from the Latin roots “fibro” (connective tissue), “my” (muscles), “al” (pain), and “gia” (condition of).” Since 1990, Fibromyalgia has been recognized as a chronic, painful, non-inflammatory syndrome involving the muscles, and not the joints. This disease is considered the third most prevalent rheumatologic disorder in the country. This disease affects nearly six million individuals in the United State, of the six million these are primarily women. Although this disease can occur at any age is more commonly found in ages ranging from 40-75. According to recent studies, it has been found that the relationship between neuro-biologic, psychosocial, and behavioral factors in the pain are associated with this disorder. There is a substantial amount of evidence that supports the relationship between stress and altered activity in the sympathetic nervous system and hypothalamic-pituitary-adrenal axis. This altered activity leads to disturbances in the stress and adaptation response. Serotonin levels also play a role in this disease. It has been shown that patients with low serotonin levels are more likely to suffer from anxiety, depression, pain, and impaired muscle function. It has also been found in laboratory testing that patients (80%) with fibromyalgia have a
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