Chronic Neuropathic Pain After Spinal Cord Injury

2271 Words10 Pages
Chronic Neuropathic Pain after Spinal Cord Injury: Spinal cord injury (SCI) affects up to 500,000 people every year around the world (Singh et al., 2014) with devastating physical, psychological and social consequences. SCI not only damages motor systems, it also directly affects sensory systems, causing chronic, debilitating neuropathic pain. The incidence of neuropathic pain after SCI is extremely high, with at least half and up to 90% of SCI individuals experiencing neuropathic pain, described as paroxysmal pain that can be continuous and may be evoked by any sensory stimulus, not necessarily painful. Current pharmacological interventions offer minimal, transient relief to a minority (30%) of sufferers of SCI-induced neuropathic pain (Cousins, 2012). Current treatment strategies utilize conventional drugs for chronic pain, which only address pain symptomatically and cannot provide lasting relief or prevent relapse of symptoms, leading to drug dependency and further reducing quality of life for SCI patients. Due to the myriad events that take place after SCI, delineating the causes of neuropathic pain development is difficult. Neuropathic pain in general, and more so in SCI, has an inherent degeneracy in mechanisms, which is likely why targeted pharmacological treatment approaches often fail to provide significant relief.

Chronic neuropathic pain after SCI is a central pain syndrome, by definition arising directly due to damage to or dysfunction of the CNS. While SCIs are

More about Chronic Neuropathic Pain After Spinal Cord Injury

Open Document