Cirrhosis Research Paper

Cirrhosis is a serious disease of the liver where scar tissue replaces normal healthy tissue, and affects the function and structure of the liver. Liver, which is the largest organ in the body, has a vital roles which are important to keep the body functioning well. Liver makes proteins and enzymes that regulate blood clotting. It also regulates cholesterol and stores the energy. In addition, the liver removes poisons from the blood. 30% of cirrhosis's victims are diagnosed will remain alive for 5 years. Cirrhosis can be defined regarding its causes, symptoms, diagnosis, and treatment.

* Edema: abnormal accumulation of fluid (aka swelling). This is important for cirrhosis because when the tissue starts turning into scar tissue, the kidneys retain more salt. This increase in salt and water causes the visualized swelling. As time progresses, this swelling can affect abdomen area of the body, making edema secondary to hepatocellular failure since it is the tissue cell morphing that causes edema to manifest.

This case study is about Abdul Chidiac, a 51 year old male, married with 4 children. He had a medical history of hypertension, hypercholesterolaemia and cirrhosis with two admissions in the last six months. He is a smoker and drinks beer, 5-6 bottles per day. As Carithers & McClain (2010) explained the patient’s medical history is another indicator of the risk for cirrhosis; the progression to cirrhosis is adaptable and may take time over weeks or many years. Cirrhosis is a liver disease characterized by permanent scarring of the

Alcoholic cirrhosis involves the replacement of normal liver tissue with scar tissue called fibrosis. This gradual process affects the normal structure and regrowth of liver cells and the liver gradually loses its ability to function well.

According to the Clinical nutrition the possible causes of damage to the liver would be alcohol it can ruin your tissue damage around the liver. But there is Clinical Relationships many researchers do claim that the body detoxicates is strongly influenced by drugs and alcohol, they have body detoxification system influences the way alcohol acts and are metabolized. Alcohol damages cellular activities , the physical consequences become much apparent , when people become dehydrated after drinking so much alcohol and very malnourished and there alcohol trouble start to bring out both short and long term

The progression from fibrosis to cirrhosis, the end-point of CLDs, is distinguished by a prolonged inflammatory and fibrogenic process that leads to an abnormal angioarchitecture distinctive for cirrhosis. Several mechanisms are responsible for the angiogenic switch during the pathogenesis of CLDs. First, CLDs are characterised by chronic inflammation. Increased intrahepatic vascular resistance is primarily caused by anatomical changes, such as fibrotic scar tissue compressing portal and central venules. In addition, the formation of fibrotic septa, as well as sinusoidal capillarisation, can result in an increased resistance to blood flow and oxygen delivery. This results in hypoxia and the transcription of hypoxia-sensitive pro-angiogenic

* Other treatments - Cirrhosis of the liver is incurable but, in some cases, treatment can help to reduce the likelihood that the condition will become worse. Options include: treating the underlying cause of liver damage - for example, treating the underlying hepatitis (B or C) virus infection, removal of blood to lower iron levels in haemochromatosis ,making dietary and lifestyle changes - a nutritious low-fat diet. high-protein diet and exercise can help people to avoid malnutrition. Taking certain medications - such as beta-blockers to reduce blood pressure and lower the risk of bleeding, diuretics to remove excess fluid Avoiding certain medications that can make the symptoms worse - such as non-steroidal anti-inflammatory drugs (NSAIDs), opiates or sedatives ,having regular medical check-ups - including scans to check for liver cancer, having regular endoscopic procedures to check whether there are varicose veins within the oesophagus or stomach.

According to the Mayo Clinic Staff, cirrhosis is a late stage of scarring (fibrosis) or damage of the liver. Once the liver is injured it tries to restore itself. Once restored, it forms scar tissue. The more scar tissue formed, the harder it becomes for the liver to function. Cirrhosis is irreversible and there are different causes of cirrhosis, such alcoholic abuse, viral hepatitis or cryptogenic cirrhosis—this occurs when doctors are unable to find the cause of the condition. If diagnosed and treated early, the damage would be limited. In its advanced

Cirrhosis refers to a combination of liver diseases that interfere with the normal function of the liver after destroying liver structures. The disease causes the formation of scar tissue in the liver that kills liver cells thereby causing inflammation (Fabris 716). The cells that have survived would tend to multiply rapidly to replace the dead cells. It results to regenerative nodules in the scar due to clustering of the newly formed liver cells. Cirrhosis is caused in varied ways that range from the chemical cause like alcohol to viruses. Besides, heavy and toxic metals like mercury, lead, copper and iron cause cirrhosis if they accumulate in the liver. The liver is a detoxicating organ of the body that purify

They all damage the liver because they force it to overwork when trying to filter the blood and remove all the toxins. So once the liver exceeds its limit, it begins to deteriorate and stop functioning properly. Additionally, research have shown that these substances can have a part in causing liver cancer. There are two forms of liver cancer: hepatocellular carcinoma and cholangiocarcinoma (which is actually cancer of the bile duct). Hepatocellular carcinoma is the more prevalent form of both and is the 3rd leading cause of cancer-related deaths in the US. Signs of liver cancer include the feeling of pain or a lump in the right side of the body right under the ribcage. Jaundice is another clear symptom of liver problems. Jaundice is the yellowing of the skin and eyes, accompanied by a dark colored urine. It is caused by the liver’s inability to filter blood, so the toxins pile up and can be observed in the skin or

Characterized by progressive tissue injury and scarring, cirrhosis is among the leading causes of chronic liver failure in the United States. Recent research conducted by the National Institutes of Health indicated that the prevalence of cirrhosis, especially in clients diagnosed with Hepatitis C, has increased steadily throughout the past decade and will likely continue to increase in the future (Kanwal et al., 2011). Caused by recurrent tissue damage and inflammation, cirrhosis occurs as healthy hepatocytes (liver cells) are replaced by fibrotic and non-functional scar tissue through natural healing processes. Although liver tissue is normally very resilient, sustained injury eventually

The assessment of hepatic vein morphology has been shown to be a good indicator of cirrhosis. Examination of hepatic vein wall is recommended to be performed in segment 5 or 6 (Vessal et al., 2009). Also, changes in the dynamics of portal venous circulation correlate with progression of cirrhosis in ultrasound. Portal hypertension occurs once portal pressure reaches 5-10 mmHg above normal as a complication of cirrhosis, with recognized effects as development of splenomegaly and collateral portal venous anastomoses (Taylor et al.,

One of the indispensable organs in the human's body is the liver. It's extremely hard to live without a sound liver because of its impacts about every organ in the human body. The fundamental characteristic of disease that influence the liver are focal liver diseases and diffused liver diseases. The diffused liver diseases harm the whole liver surface, for example cirrhotic and fatty. Focal liver diseases which affect the small area of the liver surface, such as Carcinoma (HCC), Hemangioma (Hem), and Cyst. The Figure 2 represents the US images of the three focal liver diseases of the liver.

Alcohol or ethanol is a chemical compound which is classified as a depressant. Depressants slow down the human brain and affect the way the brain interprets information and alters feeling and human behaviour according to (alcoholthinagain, 2017). Alcohol just like any other liquid must pass through the stomach, from there it must pass through the liver. According to (myDr, 2017) the liver must process the alcohol into a chemical compound called acetaldehyde. The acetate is further metabolised and eventually leaves the body safely. However, if excessive alcohol is consumed over a prolonged period of time will result in alcohol related liver disease, from alcohol related fatty liver disease to worst case scenario of cirrhosis. Cirrhosis occurs in response to excessive damage felt to the liver, each time the liver is damaged it attempts to heal itself, in the process creating scar tissue.

Liver failure is the acute failure of the liver to perform its body function. Proteins that allow the blood to clot are not produced so the patient bruises and bleeds easily. A viscous fluid will sometimes collect