Cirrhosis Syndrome

As the Directors at the Sharp Rees Medical Facility, we will be talking about the liver. The liver is a very important organ in the human body as it does not just perform one function but is involved in multiple tasks. Some interesting facts about the liver; it weighs under five pounds, it has a shape like a half football and everyone is born with one. Just like most other disease or disorder, if the liver has not been taken care of properly there are many negative outcomes that can affect and destroy the liver. There are many complications when the liver is abused or damage for example cancer, hemochromatosis, gallbladder or

Cirrhosis is a serious disease of the liver where scar tissue replaces normal healthy tissue, and affects the function and structure of the liver. Liver, which is the largest organ in the body, has a vital roles which are important to keep the body functioning well. Liver makes proteins and enzymes that regulate blood clotting. It also regulates cholesterol and stores the energy. In addition, the liver removes poisons from the blood. 30% of cirrhosis's victims are diagnosed will remain alive for 5 years. Cirrhosis can be defined regarding its causes, symptoms, diagnosis, and treatment.

Cirrhosis is the eighth leading cause of death in the United States and the thirteenth leading cause of death worldwide.1 Cirrhosis is the irreversible fibrosis of the liver characterized by hepatic architectural distortion secondary to fibrous tissue and the formation of regenerative nodules.2 These anatomical changes cause hepatic vascular resistance and an increase in blood flow leading to portal hypertension. Porto-systemic collaterals develop in order to overcome the increased portal pressure gradient.3 Nitric oxide, an endogenous vasodilator is also released in effort to overcome portal pressure with the expense of causing systemic vasodilation and a decrease in blood pressure. As a result, a marked activation of neurohumoral vasoactive factors occurs in an effort to maintain an effective arterial blood pressure. Hypervolemia, increased cardiac index, decreased systemic vascular resistance, and systemic hypotension are manifestations of portal hypertension.3 Chronic hepatitis B virus (HBV), hepatitis C virus (HCV), alcoholism, nonalcoholic steatohepatitis (NASH), and non-alcoholic fatty liver disease (NAFLD) are all major causes of cirrhosis.

This case study is about Abdul Chidiac, a 51 year old male, married with 4 children. He had a medical history of hypertension, hypercholesterolaemia and cirrhosis with two admissions in the last six months. He is a smoker and drinks beer, 5-6 bottles per day. As Carithers & McClain (2010) explained the patient’s medical history is another indicator of the risk for cirrhosis; the progression to cirrhosis is adaptable and may take time over weeks or many years. Cirrhosis is a liver disease characterized by permanent scarring of the

Cirrhosis is a consequence of chronic liver disease characterized by replacement of normal, healthy liver tissue by fibrotic scar tissue, blocking the flow of blood through the organ and preventing it from working as it should, as well as regenerative nodules leading to progressive loss of liver function. The liver, the largest organ in the body, is vital in keeping the body functioning properly. It removes or neutralizes poisons from the blood, produces immune agents to control infection, and removes germs and bacteria from the blood. It

Cirrhosis is the 12th leading cause of death in the United States. Cirrhosis affects one of the largest organs in the body, the liver. It is a condition that slowly worsens the liver and is unable to function normally due to chronic injury. Cirrhosis consists of four stages with the fourth stage being the most advanced stage of cirrhosis. When healthy liver cells are damaged and replaced by scar tissue (fibrosis) it’s known as a degenerative disease called cirrhosis. Chronic alcoholism is the leading cause of cirrhosis due to excessive drinking of alcohol, which causes the liver to swell. In sequence with alcoholism and hepatitis C, or alone obesity can be a risk factor in developing cirrhosis. Cirrhosis of the liver is a disease that can affect many individuals if the condition is not caught in early stages it can become deadly.

The liver is the largest gland and second largest organ in the human body. It is also the only internal organ capable of regeneration following injury. Located in the abdominal cavity, this reddish brown organ is divided into lobes of different size and shape. The liver plays a critical role in metabolism, digestion, elimination, and detoxification, among other processes. This organ performs a surprisingly large number of functions that influence virtually all other body systems. This is why diseases of the liver can be so devastating. One class of chronic diseases affecting the liver is cirrhosis. (Kasper, 2008)

Cirrhosis of the Liver is a horrible disease that takes the lives of many people every year. There are many causes, symptoms, ways to diagnose and treatments that surround this disease as well as many ways that this fatal disease can be prevented.

Cirrhosis is a condition that results in development of fibrosis in liver, resulting in decrease in

Fibrosis and Cirrhosis are two pathological conditions. Liver fibrosis is first stage of liver scarring characterized by the excessive accumulation of extracellular matrix (ECM), which

So then, hypertrichosis is an abnormal of hair growth over the body; extensive cases cases of hypertrichosis have informally been called werewolf syndrome. One of the human oddities for instance has werewolf syndrome. His name is Jo-Jo; the dog-faced boy is his common named (Pednaud, 2014, sect. 3). The most common type of this condition in freak shows are the bearded ladies. Which also dates back centuries ago like, Percilla, The Monkey Girl; she was a very commonly known for her time. Her dad at a young at did not know how to handle his daughter’s condition, so he sold her to a show. He died shortly after. She was not to upset about being sold. She found love in the show and married someone who also worked in the show (Pednaud, 2014, sect.

Some preventions that can be done to avoid having cirrhosis is to stop bad habits such as large alcohol consumption, cigarette smoking and eating too much. Antioxidant-rich foods and drinks can prevent cirrhosis as well. People who have specific conditions should take some antiviral medicine to prevent the complications of getting hepatitis B or C. By doing this, the next step that could have happened which is getting cirrhosis would be prevented. All patients with cirrhosis who are positive for HBsAg should get an oral antiviral therapy using entecavir or tenofovir antiviral medicines.

Hepatic fibrosis and cirrhosis are potentially reversible with timely intervention. [1] To achieve the best possible outcome, treatment must be initiated in the early stages of liver fibrosis.[1] Another benefit of timely treatment of fibrosis and cirrhosis is the prevention of hepato-cellular carcinoma.[3, 6] Additionally, in patients with chronic hepatitis C,anti-viral treatment is indicated with severe fibrosis. [3, 6]Therefore, clinicians must serially monitor the level and severity of fibrotic tissue, to ensure timely treatment and to determine the patient’s risk of liver-related morbidity, mortality and hepatic comorbidities, for example, portal hypertension or hepatic carcinoma.[7-10]

Liver cirrhosis is a disease, usually caused by excessive alcohol consumption over many years, wherein the liver shrinks and becomes hardened. In this state it is ineffective at removing toxins from the body, leading to a variety of serious health problems.

Manuscript History: Received: 14 October 2015 Final Accepted: 22 November 2015 Published Online: December 2015 Key words: Portal vein, Thrombosis, risk factors, cirrhosis. *Corresponding Author