Running head: CLOSTRIDIUM DIFFICILE Clostridium difficile Jane Doe A University Clostridium difficile Pathophysiology Clostridium difficile is a gram positive, spore forming anaerobic bacillus, which may or may not carry the genes for toxin A-B production (Nipa, 2010). These two types of protein exotoxins produced by the Clostridium difficile bacillus, toxin A and toxin B, can have an infectious form and a non-active, non-infectious form (Grossman, 2010). The infectious form can survive
Clostridium difficile BIS 222-001 Lillian Armoush (Introduction, Causal agent, and Epidemiology) Katelyn Ryan (Transmission, Clinical features, and Diagnosis) Jeremy Vasquez (Treatment, Prognosis, Control measures, and Conclusion) Introduction Clostridium difficile (C. diff) is a type of bacterium that can cause a person to endure diarrhea like symptoms to more drastic symptoms that may involve inflammation of the colon. Most people who come across C. diff are expected to be in a hospital
| | | | | Clostridium Difficile | Clostridium Difficile The healthcare professional can expect to encounter various conditions within their scope of experience. Clostridium difficile represents one of the most common and challenging nosocomial infections that can cause life-threatening complications such as hypervolemia, sepsis, pain, and peritonitis (Grossman and Mager 155). The recognition, diagnosis, treatment and inhibition of transmission of this bacterium are
of Relapse Following Clostridium difficile Infection Using Probiotic Lactobacillus casei Shirota This article, which was submitted for review in 2013, was written by Lennard YW Lee, Ramez Golmohamad, and George MacFaul of the Department of Gastroenterology, Milton Keynes NHS Foundation Trust, Standing Way, Milton Keynes MK65LD, United Kingdom. The paper was accepted for publication August 25, 2013. Clostridium difficile (C. difficile) is an anaerobic, Gram-positive, bacillus-shaped bacterium that
History Clostridium difficile was discovered and isolated from neonates in 1935. It was initially considered a component of the fecal flora of newborns and not thought to be pathogenic (Keessen, Gaastra, & Lipman, 2010). The history of C. diff and other antibiotic resistant pathogens are closely related with the history of antibiotics. The first antibiotic discovered was penicillin by Alexander Fleming while working with Staphylococcus. With this discovery, a surge of natural and synthetic drugs
difficile Clostridium difficile is an anaerobic, Gram-positive bacillus spore-forming, toxin-secreting bacteria that has long been recognized to be the most common etiologic pathogen of antibiotic-associated diarrhea(Shin Jh).It is a frequent environmental organism which has been isolated from soil, food, water, animals, asymptomatic infants, and health care environment (.Amit s,. Studies shows that only 7-15% of healthy adults are colonized with toxigenic C.difficile((Alison L) The spores of C.difficile
vancomycin for Clostridium difficile Infection? Background: Clostridium difficile is a spore forming, anaerobic, toxin-producing, gram-positive bacillus that is the most common cause of nosocomial, antibiotic-associated diarrhea (15-25%).1,2,3 The pathogenesis of C. difficile-associated diarrhea (CDAD) is the result of broad spectrum antibiotics, such as clindamycin, flouroquinolones or ceftriaxone, which reduces the population of normal bowel flora and allowing for an overgrowth of C. difficile.1,2 The
Clostridium difficile is a Gram-positive, spore-forming, rod-shaped bacillus that is renowned for being the leading cause of hospital-acquired diarrhea in adult patients. C. difficile is present as normal intestinal flora within 3% to 5% of healthy people2, while its spores are ubiquitous in the environment, especially in hospital settings. It grows at an optimal temperature and pH of 37ºC and 6.5–7.5 respectively.1 It is an obligate anaerobic as it thrives in the absence of oxygen. It is highly