Cns Tumors Research Paper

A person has a 0.55–0.7% chance of developing any type of brain tumor in their lifetime (Mohammadi and Schroeder 1). A brain tumor is a mass of abnormal cells located somewhere in the brain. Brain tumors can be caused by many different disorders including Tuberous Sclerosis Complex (TSC). Some tumors caused by this disorder are inoperable. Inoperable brain tumors can now be treated using new advanced technology. Technological advances provide new hope for patients who have inoperable brain tumors and TSC.

Once a person has been diagnosed with brain cancer, treatment should begin immediately. Treatment for brain tumors involves any combination of surgery, radiation, and chemotherapy. Some tumors require several different surgical procedures; some can be treated with radiation alone. Surgery is the best process to remove a brain tumor. Surgery attempts to remove most, if not all of the tumor. Once most of the tumor is removed, the rest of the tumor can be removed through a process called radiotherapy.

The primary ones include these types. Gliomas, the most common brain tumor involving the brain tissue. There are different grades and even types of gliomas. But if the tumor grade is higher, it will probably grow faster. Medullblastomas are brain tumors that in young children. Without treatment it will spread rapidly into the spinal fluid and other parts of the brain. But almost or half of the brain tumors found are benign. These types of brain tumors are usually Meningiomas and Neuromas. Meningiomas begin in the tissue membranes. Neuromas are in the nerves mostly in people over

Radiation therapy can be used anywhere in the body to treat any kind of cancer. Depending on what type of radiation therapy, it can have some side effects. The most common ones include fatigue, hair loss near the treated area, and skin darkening in the area exposed to a beam of radiation. ("Radiation Therapy for Cancer,” 1) There are also safety concerns that patients have when they are treated with radiation therapy. Many people that receive radiation therapy treatment, worry about exposing family and love ones to radiation, as well as the side effects. Radiation effects on the normal tissues are divided into acute and chronic effects (Schreiber). Acute effects occur during the course of therapy and during the post therapy period (approximately 2-3 weeks after the completion of a course of irradiation) (Schreiber).

The American cancer society estimated that 18,500 people would be diagnosed with brain tumor and those 12,760 men and women would die of brain cancer in 2005.The National Cancer Institute (NCI) estimated that 22,070 new cases of brain and other central nervous system (CNS) cancers would be diagnosed in the United States in 2009. The American Brain Tumor Association (ABTA) clarifies this statistic further by estimating that 62,930 new cases of primary brain tumors would be diagnosed in 2010. By the year 2030, there will be 26 million new cases, and the death toll will reach to around 1.7 million people. According to World Health Organization (WHO), there are more than 120 types of brain tumors.

Cancer is an incurable and unpredictable disease that, if left untreated, will likely result in death for the men, women, and children who must fight it. Sadly, approximately 36% of people will develop cancer during their lifetime, and of that percentage, fewer than 15% will survive, according to the National Cancer Institute. Along with surgery and chemotherapy, radiation is one of the few known methods for treating cancer, but it does not come without harmful side effects. While radiation therapy is currently a proven method for treating cancer, dangers to patients often outweigh its benefits, therefore a safer method for effectively treating and ultimately curing cancer.

Ependymoma is a type of brain tumor and while it is rare in adults, accounting for 2-3% of brain tumors, ependymoma is mainly found in children and accounts for around 5% of all childhood brain cancers (American Cancer Society [ACS], 2014, January 31; American Brain Tumor Association [ABTA], n.d.). The survival rate of patients with ependymoma who have survived five years after their tumor is detected is 75% Tumors occur when cells grow to excess and form a mass. While some tumors are benign, meaning that they are harmless, others are malignant, or cancerous. Ependymoma is a malignant cancerous brain tumor (“American Society of Clinical Oncology [ASCO]– Childhood,” n.d.). The tumor appears as soft, grey or red tumors and could comprise of cysts or mineral calcifications.

The DIPG tumor make up 10-15% of the brain tumors found in children. There is at least 100-150 new diagnosis an year in the United States. In North American and Europe there is around 300 diagnosis a year. Sadly only around 10% of children with DIPG survive two years from their diagnosis. The tumor associated with DIPG is located on the lower back of the brain near the top of the spinal cord on the brain stem (Patients 1 of 2). With this being located closer to the spinal cord it damages the nerve cells. Where the tumor is usually located is the part of the brain that controls many basic functions like breathing, swallowing, sleeping, bladder control, balance, and muscles that help with speech and eye

Primary brain cancer develops from cells within the brain. Part of the central nervous system (CNS), the brain is the control center for vital functions of the body, including speech, movement, thoughts, feelings, memory, vision, hearing and more.

DIPG (Diffuse Intrinsic Pontine Glioma) is a disease which strikes at the heart of childhood. At the base of the brain, just above the spinal cord is the brainstem. The tumor affects the pons area of the brainstem, supplying the nervous system function unattainable. ‘“There’s not a single drug approved”’ (Mukhopadhyay). Due to the location of the tumor, it cannot be surgically removed. Unfortunately, the only option available is Radiation that is considered temporary, with no benefits. “Chemotherapy is frequently ineffective, since anti-cancer drugs cannot cross the blood-brain barrier and reach the tumor” (Zhiping 2). In the end, leaves the patient and parents hopeless for fighting this

A brain tumor is a mass or development of irregular cells in your cerebrum or near your mind. There are different types of brain tumor exist which even are health hazardous. Essential brain tumors rise up out of the different cells that make up the cerebrum and focal sensory system and are named for the sort of cell in which they first shape. Gliomas and astrocytic tumors are the most common types of adult brain

Malignant gliomas are the most common type of primary brain tumors. As already shown in the Central Brain Tumor Registry of the United States (CBTRUS) report from 1998 – 2002, gliomas account for approximately 80 % of all malignant brain tumors and at least 30 % of all brain and CNS neoplasms (Ostrom et al., 2014). A number of putative risk factors that have been associated with brain tumors have been discussed. However, there is no clear cause for brain and CNS tumors. Less that 1 % are linked to lifestyle or environmental factors (Parkin, Boyd, & Walker, 2011). The only exposure that has been shown to affect glioma risk is ionizing radiation and has been classified as a cause by the International Agency for Research on Cancer (IARC) (Cogliano

Many people are living longer because of radiation therapy to treat cancer, but what happens after treatment is over? Most people go back to their normal life. However, some people will have their quality of life affected by late effects of radiation therapy. Late effects of radiation therapy can happen months or years after treatment and may be temporary or permanent. Some can be minor such as skin changes to the treated area, and some can be as serious as cardiovascular problems. As radiation therapy has become more advanced and more common in treating cancer, professionals in medicine have studied the treatments and late effects to decide what can be done to prevent late-effects from occurring.

Glioma is a solid primary tumour that starts in the brain and has a very high mortality rate. Brain tumours are most common in adults but can also affect children. There are two types of tumours one type is called the low-grade tumour and this is the slow growing tumours that are referred to as non-malignant. High-grade tumours are fast growing and are referred to as malignant tumours. However even though there are different grades they both have the potential to cause harm. The high grade which are cancerous are the most difficult to treat this is because of highly vascularized nature of the tumour. Treating high-grade gliomas requires specific alterations within the cells. Patients who suffer from a brain tumour will have many symptoms.

Radiation therapy is the ionization of atoms in tissues resulting in formation of highly reactive radicals in a well-defined, restricted volume (1). In other words, ionizing radiations are used to eradicate tumors and at the same time preserve structure and function of normal tissue. A limitation is prevented from being a problem. If bone marrow or neuronal cells are destroyed or injured, they do not regenerate. However, with radiation therapy, these cells are often saved from injury or destruction, unless the tumor is infecting bone marrow or neuronal cells. Today, radiation therapy is the most popular type of cancer therapy in use. It is used to treat one-half to two-thirds of all cancers, which translates to more than ten percent of the population