Cohort Study Alzheimer's Disease

Adults beyond the age of 18 years will be considered eligible for the study and will be required to sign a consent for once informed of the impending study, which will however not interfere with their earlier developed care plans (LoBiondo-Wood & Haber, 2014). As a matter of precaution, all patients with Type 2 diabetes and gout will be excluded as study participants (Corbett, 2012).

experiment. The researchers told the participants that the study was only for 6 months, but in

According to the CDC symptoms of Alzheimer’s can being to show after the age of 60 and older.

There is evidence from older individuals who are deemed “clinically normal” that the process of Alzheimer’s disease starts way before the clinical diagnosis of dementia, thus suggesting a preclinical stage (Sperling et al., 2011). The criteria for the preclinical stage of Alzheimer’s Disease is broken up in three stages. Stage one consists of the presence of A displacement in the brain, stage two is the displacement of A plus neurodegeneration, and stage three is the displacement of A, neurodegeneration, and subdued cognitive deficiencies. The classification for an individual to be grouped into one of these stages is based on the amount of A levels (low levels in the cerebrospinal fluid, or high levels in the brain) and/or the neurodegenerative process (Burnham, et al., 2016).

Research shows that Alzheimer’s disease causes changes in the brain for decades prior to the first symptoms become visible, so even people who seem free of the disease today might be at risk.

Alzheimer's disease is a form of dementia that is nonreversible and develops over a period of years that affects mostly the elderly population. Alzheimer's disease can be mistaken for normal aging but personality and behavior changes sets Alzheimer's disease apart. Although Alzheimer's disease is considered an aged disease, it has been documented to affect people before the age of 65. This is termed early onset Alzheimer's disease which accounts for 5-10% of all Alzheimer's disease. Statistics conducted by the Alzheimer's Association estimates that 5.3 million people have Alzheimer's disease with an annual cost for medical care of 172 billion dollars [2]. The impact of Alzheimer’s disease on American society has caused Social

These relate to the age at which the disease first manifests itself. The occasion of early-onset is much lower than that of late-onset. There is a 10% occurrence rate for persons over the age of sixty-five, and a 50% occurrence rate for those over age eighty five. Late-onset Alzheimer's is often confused with senility due to old-age. This also makes diagnosis difficult for older patients. However Alzheimer's is not an inevitable part of the aging process, unlike a certain amount of senility. It can be helped and with new research may be prevented.

Alzheimer’s disease is a very slowly progressive disease that occurs inside the brain in which is characterized by damage of memory. Also this type of disease can lead into interruption in language, problem solving, planning and perception. The chance of a person developing Alzheimer’s disease increases enormously after the age of 70 (Crystal, 2009). Also people who are over the age of 85 have over a 50 percent chance of developing Alzheimer’s disease. This type of disease is not at all normal in the aging process and is also not something that happens out of no where in a person’s life.

I think one of the saddest day in my life was when I found out my father had Alzheimer’s disease. It took an emotional toll on me and my family members. I believe Alzheimer is much harder on me and my loved ones than on my grandfather; because he was unaware of what was going on. It’s painful watching my grandfather degrade and get worse each and every day. The worst thing is that he doesn’t even know who I am anymore. In this paper I will discuss certain risk factors, background of Alzheimer’s,

They were able to locate 354 local residents who did not have known dementia. They located 506 local people in 1999 from SMS47. “The Aberdeen cohorts were studied from ages 77 to 88 (SMS32) and from age 64 to 68 (SMS47)” (Whalley et al., 2011). The researchers wanted to identify major childhood influences in risks for dementia and they believed that because the proposed risk factors for AD were found equally in childhood (e.g. years of fulltime education, childhood intelligence, socioeconomic adversity, death of a parent, family history of dementia, APOE e4 carrier status) as compared to in late life (e.g. deficiencies of the vitamins B6, B9 and B12, head injury, sedentary lifestyle, risk factors for vascular disease). Data would be required from a long life course to build a full model of Alzheimer risk. They were able to use the surveys to adjust the data for the contribution of childhood mental ability to compare to the adult behavior patterns. This gave them the estimation of lifetime change. The recognized that the lack of exposure of data, between the surveys and information gathered in the adult interviews, was an important limitation to the study design. This can be eliminated with current longitudinal studies being

In regards to Alzheimer’s disease, there are two types of the disease: sporadic and familial. Sporadic Alzheimer’s disease occurs when the disease develops with no one in the affected individual’s family having had it before. Familial Alzheimer’s disease occurs when the affected individual has a family history of Alzheimer’s disease and develops the disease due to this predisposition. It is thought that the APOE-4 gene, or apolipoprotein E-4, is responsible for familial alzheimer’s disease, as it has been shown to be present in over half of the population of those with Alzheimer’s disease and to potentially be the cause of increased plaque production within those who have the gene.

Alzheimer is a disease that affects the elderly most. The disease was discovered by Dr. Alois Alzheimer in the year 1906 when he was examining a female’s brain. He found out that the woman displayed memory loss, language problems and some inexplicable changes in behavior. The disease was named after the doctor who was a German psychiatrist and a neuropathologist. Alzheimer’s disease is a degenerative brain disorder that leads to memory loss, personality changes, and language problems (Gilbert & Julie 2). The disease is mostly diagnosed in people over the age of 65 years, though there is a small minority of people under the age of 50 who get the disease. Studies show that 1% of a whole population aged between the ages 65-75 have severe

They focused on the experiment stimuli and the response of the brain. Also, they talked about how older people and people with Alzheimer’s disease have a difficult time with estimating chronological age. “Disorientation to chronological age becomes more pronounced with dementia severity” (“Time Perspective and Positivity Effects in Alzheimer’s Disease”, 2016). It mentioned that people with Alzheimer’s Disease tend to remember more positive images than negative images. In the conclusion it talked about the results they found out and talked about how important using a variety of ages

Through focusing on the study of different brain diseases, clinical neuroscientists attempt to unravel the complex pathogenesis associated within the complex organ. Although little is known on the major causes of the brain diseases studied, age is seen as one of the most the most prominent risk factors for diagnosis (Levy, 2007). In turn, elderly populations are at the greatest risk for developing or inheriting dementia type diseases; one of these being Alzheimer’s Disease (AD). AD is a form of dementia that over time leads towards cognitive decline and eventual lessening of one’s daily activities (Colovic, 2013; Thompson, 2012). Present stats show that of 5.5 million people diagnosed with AD in America, 5.3 million are 65 or older. (Alzheimer’s

A disease is a medical condition that affects a living organism either physically, mentally or emotionally. It is basically a condition involving a pathological process along with a set of various symptoms; some easily noticeable whereas others quite difficult to detect, making their treatment process slower. (Healio.com, 2012) Nevertheless, the social and economic impacts followed by the diagnosis of the disease are generally quite drastic.