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Colon Cancer: A Case Study

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Colon cancer is one of the most common cancers found in obese people. The colon (large intestine) absorbs water and salts before the remains are passed out of the rectum as faeces and also helps to absorb remaining carbohydrates and some fats (BHIA, n.d.). Among men, a higher BMI is strongly associated with increased risk of colorectal cancer and an association between BMI and colon cancer risk is also seen in women, however, the link is weaker (NIH, 2012). In addition, people who are overweight also have a higher potential for developing gallbladder disease and gallstones which are clusters of solid material in the gallbladder made mostly of cholesterol (NIH, 2012). Researchers have found that people who are obese tend to produce higher levels …show more content…

Furthermore, obese people have a higher risk of developing fatty liver disease due to the intake of excess kilojoules, causing excess fat to accumulate in the liver, causing inflammation (BHIA, n.d.). Many researchers believe that metabolic syndrome plays an important role in the development of fatty liver (Better Health Channel, 2015). Metabolic syndrome consists of six major components: abdominal obesity, elevated blood cholesterol, elevated blood pressure, insulin resistance, elevation of certain blood components that indicate inflammation, and elevation of certain clotting factors in the blood (Stanford Health Care, 2015). Whilst metabolic syndrome affects the digestive system by causing fatty liver, this health condition simultaneously impacts the circulatory system, being the risk factor of heart disease, diabetes and stroke. All stages of fatty liver disease are believed to be due to insulin resistance, a condition closely associated with obesity. In fact, it has been found that BMI correlates with the degree of liver damage and other metabolic problems, therefore, the greater the BMI the greater the liver damage (Lee, 2007). Hence, weight loss and correcting elevated cholesterol, triglycerides and blood sugar should be beneficial in fatty liver …show more content…

Obese individuals have an increased total blood volume to meet the perfusion needs of the increased adipose tissue (Garrett, 2004). As a result, the increased stroke volume increases resting cardiac output and left ventricular work, meaning oxygen consumption is also increased, affecting the respiratory system as well as the circulatory (Garrett, 2004). More circulating blood means higher pressure on the artery walls, resulting in increased blood pressure (Stanford Health Care, 2015). Atherosclerosis refers to the accumulation of fatty deposits called plaque on the inside walls of arteries. Plaque is a combination of calcium, cholesterol, other fatty materials and blood components which attach to the artery wall lining. As a result of plaque build up, the arteries gradually narrow, eventually becoming clogged which allows less blood to flow through (NIH, 2015). This may have damaging effects on the digestive system. Furthermore, the incidence of hypertension (abnormally high blood pressure) is more prevalent in the obese (Garrett,

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