The American Cancer Society estimates that over 100,000 men and women living in the United States will be diagnosed with colon cancer in 2013. Statistically, cancers of the colon and rectum are often combined and referred to as colorectal cancer. This addition brings the total to over 140,000 affected individuals with over 50,000 of these diagnoses resulting in death (American cancer society, 2013). Globally, the impact of this disease reached over one million people in 2008 with over 600,000 deaths attributed to colorectal cancer (Dusek, Maluskova, & Musik, 2013). Colon cancer is preventable with a healthy diet, exercise, and curable with regular bowel exams. However, signs and symptoms of colon cancer usually do not present until the …show more content…
When these cells become neoplastic they begin to grow into the layers of the colon and beyond as well. This event facilitates contact with capillaries and lymph vessels and cancer cells can then break off and migrate through the entire body (McCartney & Oberleitner, 2011). The risk of cancer increases with age, and colon cancer is included in this factor with 62 being the most common age at diagnosis (McCartney & Oberleitner, 2011). Repeated exposure to carcinogens over time can cause mutations in DNA, especially in highly mitotic epithelial cells, resulting in cancerous growths. An immune response in a young and healthy body would destroy the early formation of cancer cells. Unfortunately, individuals of advanced age suffer a decrease in the capabilities of the immune system. This puts them at a higher risk of dysplastic cells multiplying in the colon. Genetics may induce the coding of certain genes within cells to undergo spontaneous mutations. (Labianca, Nordlinger, Beretta, Brouquet, Cervantes, 2010). This factor produces the cluster of colon cancers seen in families. The risk of an individual getting cancer of the colon increases when immediate family members have received a diagnosis in the past. The rate of occurrence decreases when isolated extended family members develop the disease. However, if several people in one family group such as cousins, aunts and grandparents are diagnosed, the risk for the rest of the members of that
Colon cancer is a condition in which polyps form in the lining of the colon (large intestine).
The signs and symptoms of colon cancer include blood in the stool, weight loss, change in movements in the bowel and fatigue. Most colon cancers are adenocarcinomas because they begin in the cells responsible for making and releasing mucus and other fluids. Colon cancer usually begins as a type of growth known as a polyp which forms in colon or rectum’s inner wall. Some polyps may develop to become cancer after some time. Diagnosing and removing polyps is used to prevent cancer. In the United Kingdom, colon cancer is 3rd most common type of cancer for women and men. However, deaths associated with the cancer have been decreasing after the use of colonoscopies as well as fecal occult blood tests which are used to check for the presence of blood in people’s
There are about 35,000 new cases each year in the UK. More than 80% of
“The colon cancer vs. Crohn’s disease debate is generating a lot of interest in the medical community. Every year in the U.S., approximately 57,000 people die from colorectal cancer and 147,000 new cases are diagnosed”states Dr. Victor Marchione. Crohn's disease is a new disease that was introduced into today's society in 2015. 1.4 million Americans have Crohn’s disease or ulcerative colitis. Of those, about 700,000 have Crohn’s has been diagnosed in the years between 1992 and 2004 just from a doctor's visit. People have came up with different ways that we can help and prevent the disease such as Surgery, Conferences and “ KEY TO PROCESS “.
Lynch syndrome, also known as Hereditary Nonpolyposis Colorectal Carcinoma (HNPCC), was characterized in 1966 by Henry T. Lynch. His research in the 1960’s was prompted by a single patient’s response. According to (Lynch & Lynch, 2004, p. 182), “…the patient’s response was that he knew that he, like “everyone” in his family, was going to die of cancer, and that it would likely be cancer of the colon, although he realized that many other cancers had also affected the family” (p. 182). Years of research involving this patient’s family led to a common connection. Family N showed a well-defined autosomal dominant mode of genetic transmission of carcinoma of the colon with early age of cancer onset, multiple primaries, and with the integral association of carcinoma of the endometrium and ovary (Lynch & Lynch, 2004, p. 182-183). Therefore, it was found that gene mutations put a person at high risk for CRC and endometrial cancer at a much younger age. Since then, Lynch
What is Mr. Watt’s risk factors related to colon cancer? Consider all aspects of his health, his family history and his culture.
Only about 6% of all colorectal cancer is said to be hereditary. Sporadic, or non hereditary colorectal cancer, makes up the other 94%. Hereditary colorectal cancer is made up of two syndromes- HNPCC (Hereditary Non Polyposis
Unlike other forms of cancer where the growths or tumors are malignant from stage one, colon cancer starts with small polyp on the lining of either the rectum or the colon. Initially, these small growths are seldom cancerous, which means that if removed in time, they would pose no risk at all.
Over the past decade incidence rate of colorectal cancer remained very much static but mortality rate has been improved, largely due to early detection and advancement in cancer treatments (Baade 2011) As per NICE, half of the patients in UK survive after 5
Prevention includes regular checkups, if found early enough “survival rate is 90%”, however only 4 out of 10 people find colonic cancer in this stage due to lack of regular checkups. Prevention also includes consuming the recommended amounts of fruits, vegetables, whole grains, and vitamins high in calcium and vitamin D. Risk factors include drinking, smoking, obesity, low activity, and a history of polyps.
The NHS have found that bowel cancer is one of the most common cancers in the UK, with around 40,000 new cases being diagnosed every single year. This means that approximately 1 in every 20 people will develop bowel cancer at some point within their lifetime. However, the earlier it is detected, the higher the rate of successful treatment and survival. This is why bowel screening is so important. It has been found that around 90% of those who suffer from bowel cancer are over the age of
Concerning for group of age, the people who are above 65 years the odds ratios of colon and rectal cancer were higher than people who are between 45-65 year (Crump, Guess, 1982, pp346)."Increased risks of rectal, bladder and colon cancer of the magnitudes suggested by these studies are large enough to be of concern yet small enough to be very difficult to separate from confounding risks associated with other environmental factors".
There are many risk factors for stomach cancer. Gender is a minor risk factor because men are more likely to get stomach cancer than women are. Age is a risk factor as well because most people are over the age of 65 when they are diagnosed with stomach cancer. Ethnicity is a big risk factor because the rate cancer is higher in Hispanics and African-Americans rather than non-Hispanic white. Tobacco use is a risk factor for stomach cancer along with most of every other type of cancer. Smoking doubles the risk for someone to get cancer. It has been proven that people with Type A Blood are more likely to get stomach cancer as well. Some other risk factors are things like bacteria infection, diet, earlier stomach surgery, stomach polyps, and oddly enough, some occupations in coal, metal, and rubber industries are even risk factors of stomach cancer.
Colorectal cancer mainly starts at colon or the rectum. They are common in most of the way like features, but they have different treatment. What is the different between colon cancer and rectal cancer? Colon cancer happens first four to five feet of the large intestine and rectal cancer happens in the last few inches of the large intestine where it is connected to anus. (cancercenter.com)
Colon cancer: a non-infectious cancer that shows primarily in adults over the age of 75. Arthur et al. (2012) provide evidence that inflammation in the intestines promotes an increase in harmful bacteria: genotoxic E. coli. This expanse of cancer through the intestines aids tumorigenesis, ultimately forming the perfect environment for cancerous polyps to form.