Colorectal Cancer : Cancer And Cancer

The signs and symptoms of colon cancer are diarrhea and constipation that may last more than a few days. Also, cramping or belly pain, weakness, fatigue, and unintended weight loss. A medical professional diagnose the patient by finding something suspicious during a screening exam, if there are signs of colon cancer the doctor will recommend an exam. Some exams that can be done are a CT scan, colonoscopy, and biopsy, there are many more ways to find out if you have colon cancer. A CT scan is a scan "to make detailed cross-sectional images of your body". A colonoscopy "the doctor will look at the entire length of the colon and rectrum with a colonoscope (a thin, flexible, lighted tube with a small camera at the end)." Biopsy test

Colon cancer is a condition in which polyps form in the lining of the colon (large intestine).

Colorectal cancer mainly starts at colon or the rectum. They are common in most of the way like features, but they have different treatment. What is the different between colon cancer and rectum cancer? Colon cancer happens first four to five feet of the large intestine and rectal cancer happens in the last few inches of the large intestine where it is connected to anus.

Mr BW was a 74-year-old man who had a fall due to a new onset of seizures, which resulted, to a direct impact of his head on the ground while at home. While at the hospital, MR BW underwent a CT and MRI brain scan and showed a haematoma, which resulted to commencing of the patient on Keppra and Bezodiapenes. Moreover, Mr BW also developed a sudden onset of pleuretic chest pain, which was confirmed by CTPA as a small pleural effusion on the left lungs; while there was also pulmonary embolism on both upper and lower lobes of the left lung. Due to the development of a provoked pulmonary embolism, patient commenced on Clexane injection. In September 2015, an elective open abdominoperineal resection was performed on Mr BW, which resulted to prolonged stay in the hospital due to delayed wound healing.

There are over 100 types of cancer. One type is called colon cancer, a very common disease in the lower part of the digestive system. Colon cancer is luckily very treatable if caught early, but because it is so common it is the second leading cause of death from cancer. About 140,000 people in the U.S. are diagnosed with colon cancer every year.

Familial adenomatous polyposis (FAP) is a genetic disease that can be inherited. If a person has FAP, they are likely to get colorectal cancer. If FAP is not treated, there is about a 100% chance you will receive colorectal cancer. FAP produces growths with mucus on the inside walls of the colon and rectum. The growths are called polyps. You can get between 100 and 1000 polyps in just 10 years. The genetic test that they run for FAP is a blood screening test for the adenomatous polyposis coli (APC) gene. The blood test is for checking for a mutation in the APC gene. If the results are positive, closely related family members should be tested too. You should also be tested if colon cancer is hereditary, or if you have a history of more than

Imagine having an almost 100% chance of developing colon cancer. That is what people are told with Familial Adenomatous Polyposis (FAP) if they do not have their over 100 polyps, or growths, removed. FAP is a genetic disorder where normal cells that line your large intestine can grow into cancerous tumors. These tumors must be removed before they become cancerous. This disorder is passed down from parents on the APC gene which is on your fifth chromosome. If the APC gene is mutated you are more likely to develop these growths which lead to cancer in your lifetime. This disorder has an autosomal dominant inheritance pattern, which means if either parent has just one dominant mutated APC gene you have a 50% chance of inheriting it. Symptoms of FAP do not just include the growths in your colon. They can also include skin changes, osteomas or bone growths, and extra or missing teeth.

Lynch syndrome (LS) is a genetic disorder which increases the risk for other types of cancers and can have

Imagine a cancer that creates cancer. Lynch syndrome, which is also known as hereditary nonpolyposis collectral cancer (HNCC) is an inherited disease that is a passed down trait that increases your chance of colon cancer and other cancers as well. The cause is the trait being passed through families. There are no symptoms since it is simply passed down. They just have increased probability of developing bowel, colon and other cancers.

Colon cancer is expected to be responsible for about 47,700 deaths (23,100 men and 24,600 women) during 2000. About 8,600 people (4,700 men and 3,900 women) will die from rectal cancer during 2000. The death rate from colorectal cancer has been going down for the past 20 years. This may be because there are fewer cases, more of the cases are found early, and treatments have improved.

This condition is known as the familial adenomatous polyposis which one of the main precursors to the development of colorectal cancer (P, 2013). This condition is inherited and is as a result of a genetic mutation in the gene that codes for the APC protein (a tumour suppressor gene). It starts out as a benign tumour but has the tendency to progress onto a malignant form as in the case of our patient. (Flemming et al., 2012).

Colorectal cancer is the third most common cancer among men and women in the United States, and mutations in the MUTYH gene significantly increase the risk of developing polyps that may evolve into cancer.1,2 Biallelic mutations in the MUTYH gene can lead to MYH-Associated Polyposis (MAP), which causes the growth of dozens to hundreds of polyps, furthering increasing the risk for colon cancer.2 Meanwhile, recent studies have shown that both biallelic and monoallelic mutations can contribute to bladder, ovarian, gastric, hepatobiliary, endometrial, and breast cancer.3 The MUTYH gene itself codes for the MYH glycosylase enzyme, which repairs mistakes in DNA caused by reactive oxygen species.3,4 Also a sign of oxidative stress, the oxidation product, 8-oxo-7,8-dihydro-2-deoxyguanosine (OG), mimics thymine, eventually matching with adenine and resulting in a complete loss of the cytosine-guanine pair.4 MUTYH removes the undamaged A base from the mismatched pair, aiding in the correction of such damage.4 However, when MUTYH is mutated, there is an increase in G to T mutations, which can eventually affect the tumor suppressor genes APC and K-ras and lead to tumor formation.4 The MUTYH variants Y165C and G382D are the most common mutations seen in individuals with MAP, and for this reason are of great interest in research working towards reducing the risk of colorectal cancer.2,4 In recent years, the CRISPR/Cas system for gene editing has become the preferred method for

(WENY) - Every year nearly 50,000 people die of colon cancer in the United States and is the third leading cause of cancer related deaths.

Lynch syndrome, previously known as hereditary nonpolyposis colorectal cancer (HNPCC) is a parental inherited condition that exposes a person to the risks of cancers, but most commonly colon cancer1-9. It is a heterozygous autosomal dominant genetic condition, which means that if only one parent carries the gene for Lynch syndrome (LS), then a 50 percent chance of passing on the mutation will be passed to each child1-9. LS is limited to families with a known pathogenic germline mutation2. A germline mutation is when mutations occur in the germ line, which is a group of cells that contribute to the improvement of gametes2,3,10. To find out how individuals are to contract this disease, the family medical history must be taken into account. Early

Colorectal cancer mainly starts at colon or the rectum. They are common in most of the way like features, but they have different treatment. What is the different between colon cancer and rectal cancer? Colon cancer happens first four to five feet of the large intestine and rectal cancer happens in the last few inches of the large intestine where it is connected to anus. (cancercenter.com)