Colorectal Cancer : Disease Risk Factor Research Paper Essay

I was deeply touched when my grandfather was diagnosed with widespread colon cancer several years ago. Being naïve at the time, I thought “why is cancer so bad, can’t it be cured just like the flu?” From my Biology and Genetics courses, I realized that cancer was a complex problem that was not fully understood, despite many advances. To my surprise, I found that cancer was the second leading cause of death according to the CDC website. This sobering statistic spiked my curiosity and led me deeper into the topic. I became intrigued by cellular pathways and how missteps in the pathways could result in cancer. It also struck me that most discoveries were confined to labs and research papers without ever reaching patients. I decided to become a scientist and do my part to advance the understanding of

In 2015, 132,700 people will be diagnosed with colorectal cancer (CRC) and 49,700 people will die from the disease (ACS, 2015). According to the CDC, 1 in 30 cases of colorectal cancer can be attributed to Lynch syndrome (CDC, 2015). Using figures from 2015, that would be 3,981 new colorectal diagnoses related to Lynch syndrome. Livstone (2014) states, “Patients with one of several known mutations have a 70 to 80% lifetime risk of developing CRC”.

In the United States (U.S.), colorectal cancer (CRC) is the second major cause of cancer associated deaths. During 2008-2012, per year incidence and mortality counts due to CRC were 42.4 and 15.5 per 100,000 men and women [2]. However, during 2008-2012 the incidence rate of CRC in AA population was 101.2 (16.89% higher) as compared to 84.1 of CA per 100,000 men and women. Moreover, the number of AA deaths associated with CRC was 47.5 (54.72% higher) in comparison with 30.7 CA deaths per 100,000 men and women [2]. CRC patients of AA

Rectal cancer has long been recognized as one of the common malignancy in developed and developing countries. It is one of the major causes of cancer related mortality in the world1. Early detection, early diagnosis and timely treatment results improvement in the survival rate among rectal cancer.

Your colon is the large intestine in your body. Colon cancer is pretty self explanatory from the name, it is the cancer of the colon. The colon is the final part of your digestive tract. The digestive system is the group of organs that allow us to eat and to use the food we eat to fuel our bodies. According to mayo clinic on October 31st, 2017, most cases of colon cancer begin as small, non cancerous clumps of cells called adenomatous polyps, which over time some of these polyps can become colon cancers. Polyps can be small and they produce few, if any, symptoms. This is why doctors recommend regular screening tests that help prevent colon cancer. The way they can detect colon cancer from any stage is by identifying and removing

Colon and rectum cancer, much like many other cancers, are researched and analyzed in order to study the trends of the disease. Either of these cancers are also named colorectal cancer for reference to either colon or rectal cancer. Colorectal cancer is in the top five most commonly diagnosed cancer within the United States, standing at number four. There are 50,260 estimated deaths from colon and rectum cancer, ultimately making up the estimated 8.4 percent of all diagnosed cancers. New cases of these cancers have decreased since 1992; deaths have also decreased. Statistics show deaths and numbers of cases diagnosed have been decreasing by over two percent each year for the last ten years.

National Colorectal Cancer Awareness Month is used to bring awareness to one of many cancers that affects 1 in every 100 person, health wise. Although colorectal cancer can be preventable, it is among the list of cancers that affect both men and women. As one of the second leading causes of cancer deaths in the United States, colorectal cancer affects approximately 140,000 Americans who are diagnosed each year, leaving more than 50,000 people die from it. According to the Prevent Cancer Foundation, the list below are ways to prevent this cancer:

Colon cancer is one of the deadliest diseases in the world as most patients don’t have any symptoms in the early stages of the illness.

Morbidity and mortality are increased in patients with advanced or metastatic colon cancer, and in

Colon cancer is the third most common cancer in the United States. It affects the large intestine by growing tumorous growths which are call adenomatous polyps. The continued growth of these tumor like substance can lead to colon cancer if left untreated. The cause for colon cancer is explain by Peter Crosta from Medical News Today which says, “In most cases, it’s not clear what causes colon cancer. Doctors know that colon cancer occurs when healthy cells in the colon develops errors in their genetic blueprint,”(Colon Cancer: Symptoms, Treatment, and Causes). Being related to someone who has colon cancer increases your risk of having this. The inherited gene is passed spreading to the next member of the family. There are symptoms that occur

The Intestines (Human Anatomy): Picture, Function, Location, Parts, Definition, and Conditions. (n.d.). Retrieved October 19, 2015, from http://www.webmd.com/digestive-disorders/picture-of-the-intestines

Neufeld and her fellow scientists, the threat of colon cancer has drastically declined. Between 1975 and 2009, the five-year colon cancer survival rate increased from 48.6% to 66.4% (National Cancer Institute). Despite these improvements, colon cancer remains the fourth most diagnosed cancer, following cancers of the breast, lung, and prostate. Moreover, it causes the second most deaths, with colon and rectal cancers combining to cause over 51,813 fatalities in 2013 (CDC). Scientists’ work to improve the diagnosis of colon cancer is particularly crucial, as it is commonly referred to as a “silent killer”. Oftentimes, it has no accompanying symptoms and people decide not to be tested via a colonoscopy. Once symptoms arise, the cancer tends to be in an advanced stage, at which point survival rates plunge from 90% to 10% (American Society for Gastrointestinal Endoscopy). Should a novel, noninvasive method be developed to predict and diagnose colon cancer, it is likely the survival rate would increase exponentially in the

Colorectal cancer is becoming an increasingly greater threat of death from cancer but if caught early the survival rate increases about 90% so screening is very important as a diagnostic tool.

The immune system has a way of detecting and destroying cells that are abnormal, which can cause cancer in the human body. In most rare cases some cancers are able to avoid the detection in the immune system. Colorectal cancer (CRC) is also known as colon cancer, it is part of the digestive system that is called the gastrointestinal system. It occurs in the large intestines that are located in the lower part of digestive system. Colon cancer usually starts small adenomatous polyps, which are noncancerous clumps of cell (Mayo clinic 2013). As time progress these small adenomatous polyps will eventually become colon cancer. The granulocytes colony stimulating factor (G-CSF) it occurs mostly in human and mouse CRC. In humans

Colon cancer is cancer in your large intestines. Colon cancer usually starts with polyps, which are small benign groups of cells. Over time the polyps may become malignant. Some symptoms of colon cancer are bloody stools, changes in bowel habits, and a feeling that your bowel does not feel completely empty. There are no clear causes of colon cancer, but we do know that it happens when healthy cells in the colon develop errors in their DNA. A cell becomes cancerous when the DNA is damaged. Some people may inherit genes that can create a larger risk of colon cancer. It has also been shown that people with diets of high in fiber and low in fat have a significantly greater risk of getting colon cancer. If the cancer is found in early-stage, then