Common Forms Of Respiratory Cancer

What are lung cancers? Lung cancers are the abnormal cells which grow in uncontrolled manner in one or both lungs. They do not function as normal lung cells and do not develop into healthy lung tissue. The abnormal cells can grow, form tumours and interfere with the normal functions of the lung (Lungcancer.org, 2015). Lung cancers can be divided into two major types, namely non-small cell lung cancers (NSCLC) and small cell lung cancers (SCLC). NSCLC can be further classified into three main subtypes, namely adenocarcinoma, squamous-cell carcinoma and large-cell carcinoma (Longo & Harrison, 2012). Lung cancers can be diagnosed by chest X-ray, computerised tomography (CT) scan, positron emission tomography-computerised tomography (PET-CT) scan, bronchoscopy and biopsy (Nhs.uk, 2015). Unfortunately, lung cancers are often diagnosed at the later stages. This is due to the unrecognisable symptoms and warning signs at the earlier stages. NSCLC are often diagnosed at stage IV which accounts for 30-40% of cases whereas 60% of SCLC is diagnosed at stage IV. Lung cancer usually originates from the cells lining the bronchi, bronchioles and alveoli. Carcinogens especially tobacco smoke will alter the gene expression of the normal human lung cells, resulting in cell mutation. The proto-oncogenes will be converted to mutated form, oncogenes. Mutation leads to the decreased expression of the tumour suppressor genes. This results in uncontrolled cell proliferation, cell

Throughout life, many individuals experience difficulties due to growing up in everyday life. While going in depth of the human life, it is discovered that there are many diseases and disorders that affect humans’ everyday functions. A very popular disease that has traumatically affected the human body is cancer. Cancer is a disease that spreads throughout your body in many ways. The purpose of cancer is to attach to a blood cell in your body and cause a plague within itself, causing the body to initially shut down and die. This disease contains many forms and have many causes to it. However its main goal is to destroy the human body.

However, there are stages in the lives of all humans when the body finds itself in a position where it is no longer able to defend itself against ailments and diseases and eventually may even lose the battle. One such disease which claims many lives every year in this manner is Cancer. So far so, there has been no cure for Cancer but some medicines and treatments are now available which can slow down and in some cases can even alter the effects of Cancer, depending on the stage at which the disease is at that moment. For this paper however we would concentrate on Lung Cancer and its effects.

Lung cancer is a cancer (malignancy) that originates in the tissues of the lungs or the cells lining the airways. Lung cancer originates when normal lung cells become cancer cells, usually after a series of mutations, and begin to divide out of control.

The leading cause of cancer death for both men and women in the United States and worldwide is lung cancer. Lung cancer is responsible for thirty percent of cancer deaths in the United States. The deaths caused by breast cancer, colon cancer and prostate cancer combined do not add up to the deaths that lung cancer causes. In 2007, 158,683 people, 88,243 men and 70,354 women died from lung cancer in the United States (Eldridge, 2012). Out of the 158,683 people that died from lung cancer in 2007, 135,000 of them died of lung cancer caused by smoking cigarettes. The overall survival rate of those with lung cancer is at about fifteen percent.

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Lung cancer is a genetic and acquired disease. Lung cancer is genetic because cancer in general is caused by changes to the genes that control the way our cells function, especially how they grow and divide. All of these changes include mutations in the DNA that makes up our genes. Genetic changes that increase cancer risk can be inherited from our parents, if the changes are presents in germ cells. Which are the reproductive cells of the body, those are the eggs and the sperm. Lung cancer is also acquired because as the result of errors that occur as cells divide a person’s lifetime or exposure to certain chemicals. Some examples of these chemicals are found in tobacco smoke, radiation, UV rays from the sun that damage DNA. “In general, cancer cells have more genetic changes than normal cells. But each person’s cancer has a unique combination of genetic alterations.” Some of these changes may be the result of cancer, rather than the cause. As the cancer continues to grow, additional changes will occur. Even within the same tumor, cancer cells may have different genetic changes.

Cancer, it can affect anyone; it can affect any part of the body but what is it? Cancer results from the abnormality in the body's cells. This occurs when the cells divided and grow. Disruption in the system of the growth and division of a cell results in an uncontrolled division and proliferation of cells that form a mass which leads to cancer. The patient outcome for cancer is different for everyone, but it is also different with each type. In the respiratory department, a major type of cancer we will deal with is lung cancer. Lung cancer, however, has different types and stages, but for this paper, we are going to talk about Stage IIIA non-small cell lung cancer (NSCLC). In the article titled “Stage IIIA Non-Small Cell Lung Cancer” it states

Cancer is a class of diseases in which abnormal cells multiply and divide uncontrollably in the body. These abnormal cells form malignant growths called tumors. Throat cancer refers to cancer of the voice box, the vocal cords, and other parts of the throat, such as the tonsils and oropharynx.Throat cancer is often grouped into two categories: pharyngeal cancer and laryngeal cancer. Pharyngeal cancer forms in the pharynx. This is the hollow tube that runs from behind your nose to the top of your windpipe. Laryngeal cancer forms in the larynx, which is your voice

Throat cancer is anywhere found in the throat which is also called pharynx. The pharynx is a 5” tube that runs from the nose to your neck. The larynx, known as the voice box, is found at the front of the neck. The larynx and pharynx are the main places where then cancer forms. The head and neck squamous cell carcinoma (HNSCC) will be found in the mouth, nose, and throat; it can also be spread to the lymph nodes and lungs. HNSCC can be altered to the DNA in cells; HNSCC is the most common cancer worldwide. You could develop throat cancer in your later years, most people develop throat cancer around the year 65. You can develop throat cancer by smoking cigarettes, pipes, cigars. Also, the lack of fruits and vegetables, and excessive alcohol use can lead to throat cancer.

The larynx is a part of the throat which contains vocal cords that resonate as air passes through them, resulting in our voices. This part of the respiratory system, which lies in between the tongue and trachea, is also involved with breathing and protection of the trachea from food aspiration. Several risk factors such as diet, age, excessive drinking or alcohol use and even acid reflux can increase the chances of developing cancer of the larynx. A growth may occur anywhere on the tissues of the larynx causing laryngeal caner leading you to have surgery. In many cases a laryngectomy is done to extract a tumor or growth that may eventually become malignant. It is important that before, during and after surgery we maintain care for the patient. The purpose is to optimize the delivery of safe care for post laryngectomy patients.

|Specific Purpose: |To inform readers on the causes, effects and treatments of lung cancer. |

- Usually, human cells will divide and grow into a new cell, when the cells grow old and die the

Many of the cancers besides lung cancer may develop as a result of cigarette smoking. One example is cancer of the larynx. Sometimes the larynx has to be removed because of the presence of a tumor, forcing the smoker to breathe through a surgical opening in the wind pipe. Because the larynx is located near the voice box, the voice box will often get destroyed from the tumor on the larynx, forcing the smoker to use an artificial voice box in order to speak. Less major cancers including cancers of the cheeks, gums, lips, tongue, esophagus, bladder, kidney, and pancreas may also arise.

Laryngeal cancer shows up in the vocal cords. Symptoms of this cancer include cough, coughing blood, and hoarseness. Oral cancer arises in the mouth and throat. It's most common in people who chew tobacco. Esophageal cancer is in the esophagus which links the oral cavity to the stomach. Pancreatic cancer is in the pancreas which is a secreatory organ situated at the rear of the abdominal cavity behind the stomach. Being bathed in the tobacco carcinogens which are in the blood and then concentrated in the urine causes kidney cancer. Cancer of the urinary bladder is in the bladder's surface, and the earliest symptom is bleeding. Respiratory diseases cause by smoking includes chronic obstructive pulmonary disease, respiratory morbidity, emphysema, and respiratory infections.