Essay on Common Gynecologic Malignancy: Cervical Carcinoma

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Cervical carcinoma is the third most common gynecologic malignancy with an approximate 85% of the global burden is from developing countries, where it accounts for 13% of all female cancers [1, 2]. Even though there have been significant advances in surgical techniques, radiotherapy, and chemotherapy, there are still approximately 30% of these patients with invasive cervical carcinoma who die as a result of residual or recurrent disease [3].
As the prognosis and survival has improved with advance in the management of these patients with additional radiation therapy or chemotherapy, early detection of recurrent cervical carcinoma is imperative. The follow-up after primary therapy is usually performed with clinical examination and imaging (computed tomography (CT) or magnetic resonance imaging (MRI)) [4–7]. Because of the wide availability and certain advantages, such rapid acquisition time, lack of bowel motion artifact, and fewer contraindications than MRI, CT is most widely used for follow up and is an effective diagnostic tool for detection of recurrence [4, 5]. However, the value of CT in differentiating recurrence from postoperative changes/ post radiation fibrosis is limited [6, 7]. Few studies exist in literature to confirm the usefulness of MRI over CT for diagnosis of recurrent cervical carcinoma and differentiating it from radiation fibrosis [7, 8].
Literature on the value of Multiparametric MRI (MPMRI) in diagnosing recurrence in postoperative…