Common Inflammatory Demyelinating Disease Of The Cns Essay

1906 WordsDec 18, 20168 Pages
Abstract background: Multiple sclerosis (MS) is the most common inflammatory demyelinating disease of the CNS and the most frequent cause of nontraumatic neurological disability in young and middle-aged adults (1). Women are twice as likely to be affected as men, and onset typically occurs between the ages of 20 and 40 years (2). The diagnosis Depend on a detailed history; careful neurological examination; and supportive paraclinical investigations. According to the new McDonald criteria, the diagnosis of MS requires objective evidence of lesions disseminated in space and time.MRI findings may contribute to the determination of dissemination in time or space (4). Aim of the study: the aim is to evaluate the role of MRI and find the most common findings in the early stages of the disease, which could provide the knowledge to help finding a higher quality care or even a cure to the disease. Result: we have found that the MRI is the first choice of imaging in detecting Multiple Sclerosis. From our 50 patients 15(30%/) were diagnosed by active demyelinating MS and 35 patients (7%) were diagnosed by chronic demyelinating MS. The most used sequence in all of the cases was T2 weighted, FLAIR was performed in 49 of the cases (98%), T1 after IV contrast was used in 7 cases (14%). The common findings in the active demyelinating MS were high signal intensity in T2 weighted and in Axial FLAIR, in chronic demyelinating MS was characterized by enhancement after IV contrast and
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