Common Inflammatory Demyelinating Disease Of The Cns Essay

Multiple sclerosis (MS) involves an autoimmune process that develops when a previous viral insult to the nervous system has occurred in a genetically susceptible individual. B lymphocytes, plasma cells, and activated T cells, along with proinflammatory cytokines, cause inflammation, oligodendrocyte injury and demyelination. Early inflammation and demyelination lead to irreversible axonal

Multiple Sclerosis (MS) is a neurologic disease that affects the Central Nervous System (CNS) through cellular immune response and the demyelination of CNS white matter (McCance et al., 2014, pp. 630–633). The initial causes of MS are unknown however, it is believed that it could possibly be due to an immune response to an initiating infection or an autoimmune response to CNS antigens on the myelin itself (Brück, 2005) (Miljković and Spasojević, 2013). MS is a result of the degradation of the myelin sheath surrounding neurons and therefore disrupts the transmission of action potentials along these cells. MS can display itself in the form of symptoms ranging from muscle weakness to trouble with sensation and coordination (NHS, 2016). The degradation of myelin leads the body to attempt to remyelinate the neurons, a process that in turn leads to the thickening of the cell by glial cells and this causes lesions to form (Chari, 2007). It is this thickening (sclerae) from which the disease gets its name. Sufferers of MS can either have a relapsing type of MS, in which there are episodes that lead to the worsening of symptoms for a period of time, or a progressive type of MS where symptoms gradually progress and worsen (McCance et al., 2014, pp. 630–633).

Multiple sclerosis, or MS, is a disease of the central nervous system. The central nervous system is made up of the brain and spinal cord. Both have nerve fibers that are wrapped in a myelin sheath. In MS, the myelin sheath becomes inflamed and gradually is destroyed. With the destruction of the myelin sheath comes an array of symptoms that may include numbness or tingling, balance problems, weakness, muscle spasms, and blurred vision.

Multiple Sclerosis is an inflammatory demyelinating neurodegenerative disorder of the central nervous system that has the potential to cause significant disability in those affected through the body's immune system attacking and destroying the myelin sheaths surrounding the axons. Myelin is rich in lipids and proteins that form layers around the nerve fibers and acts as insulation and protection. This damage to the myelin in the CNS, and to the actual nerve fibers, has the potential to block the transmission of nerve signals between the brain and spinal cord and also other parts of the body. This disruption of the nerve signals produces the primary symptoms of MS which then possibly lead to secondary and tertiary symptoms stemming from these

Multiple Sclerosis (MS) is a lifelong disorder of the central nervous system: that consist of the brain and spinal cord. MS is known as an autoimmune disease in which the immune system mistakenly attacks myelin sheath. The myelin sheath is the cover that protects the nerve cells. When the myelin is damaged, messages between the brain and the whole body get disrupt. MS is more probable to affect people between the ages of 20 to 40 years. The effects of the disease vary for everybody who suffers from it. Depending on this the disease may progress rapidly or slowly. MS has four different categories of progressing. Unfortunately, MS is an incurable disease, but treatments such as medication and physical therapy can help comfort and regulate the symptoms. In this essay, I will talk about the progression of the four types of MS and the stages of diagnosis.

Multiple Sclerosis is also known as MS and is a disease of the central nervous system. It is a chronic inflammation disease that is immune-mediated and attacks the protective sheath that covers the fibers of the nerve and causes problems of communication between the brain and the remainder of the body. This disease will eventually cause the nerves to deteriorate or become damaged permanently. Multiple Sclerosis has the potential to disable the brain and spinal cord. The cause of this autoimmune disease unknown. The body’s immune system attacks its own tissues.

Multiple Sclerosis is a disease that can impact many different parts of the body. It starts out by the immune system attacking the myelin that surrounds the nerve fibers in the Central Nervous System. Once the myelin tissue is damaged, it forms a type of scar tissue that essentially causes the sclerosis. It then sends nerve impulses back and forth between the brain and spinal cord that can cause many different ranges of symptoms. Scientists are still researching the cause for this disease; however, there have been great advancements since it was first discovered back in the eighteen-hundreds. From conducting research over the years, scientists have been able to collect data that gives a further insight into how MS works. There is no cure

Multiple sclerosis (MS) is a very complex disease characterized by many different pathophysiological mechanisms that play a role in how the disease presents itself and its progression (Miller, 2012). Some mechanisms that play a role in MS are demyelination, axonal/neuronal damage, inflammation, gliosis, etc (Miller, 2012). Among 20-40 year olds, MS is the most common neurological disease (Miller, 2012). There are many different causes associated with MS but the two main causes of MS are axonal injury and oxidative stress and excitotoxicity.

Multiple Sclerosis has haunted my reality as a young child. I can recall an episode that lay at the beginning memories of my childhood. The steady shifting of the bed and the sudden spike in heat surrounding me woke me from my peaceful slumber to find my grandma having a M.S episode. Multiple Sclerosis was a word that always lingered in my family at every turn, but never had I known the true meaning. Diseases are commonly discussed in television programs, papers, and daily conversation, but the normal course of the discussion goes towards scientific findings and the implementation of treatment options what science has created to cure. The disease is never really discussed in its entirety; neither are there enough discoveries on how to stop

Multiples sclerosis, also known as MS, is a disease in which a patient’s immune system attacks his or her central nervous system. Within the central nervous system, the myelin sheaths of individual nerves are attacked and damaged causing a break in communication between the patient’s brain and his and her body. The location of this disease is within the myelin sheaths on the nerves located in the central nervous system.

Multiple sclerosis, or MS, is a chronic, autoimmune, and degenerative disease of the central nervous system. Its etiology is unknown, but a combination of environmental and genetic factors is likely responsible for its development. MS occurs when one’s immune system attacks the fatty protein myelin, which insulates and protects the axons of oligodendrocytes in the brain and spinal cord. Damage to this sheath can cause the miscommunication between these oligodendrocytes and the rest of the body, and additionally causes painful and debilitating symptoms. The severity of these symptoms varies from one person to another and is dependent on the extent of the nerve damage and the types of nerves that have been affected. This disease effects one’s motor and cognitive abilities, and can oftentimes lead to severe impairment of one’s movement and speech. There is no known cure for this inflammatory disease, but medication and therapy can help alleviate the effects as the disease progresses.

However, when myelin is not present, the nerve signals no longer have any “gaps” to jump over and the nerve fibers do not receive any insulation. Multiple sclerosis means “many scars,” and this name holds true because without the myelin, the nerve fibers appear very scarred. This disease is a disabling one, and there are many symptoms of it. These include fatigue, or weakness, stiffness, tremor, swollen ankles, movement impairment, numbness, difficulty controlling bladder and bowel, pain, speech complications, dysphagia, memory problems, weight gain, loss of vision, dizziness, and pressure sores. Because there are so many symptoms of this disease, it is not always easy to diagnose it. An important way that physicians diagnose multiple sclerosis is by referring to a set of criteria published by the “International Panel on the Diagnosis of Multiple Sclerosis” . This method of diagnosis says that the patient experiences multiple symptoms occurring in the CNS. Clinicians use magnetic resonance imaging (MRI) in order to clearly see what is going on in the CNS. They look for lesions on the brain and spinal cord, which indicates that scarring is happening. When this case applies to the patient, they are said to have

Jean – Martin was the first neurologist to identify multiple sclerosis disease in 1868. Three major signs of MS are nystagmus, intention tremor, and telegraphic speech. Multiple sclerosis is also known disseminated sclerosis or encephalomyelitis disseminate which is an inflammatory disease in which of the nerve cells , brain and spinal cord becomes damaged. The damage of the nervous system causes the body to not be able to communicate, which results in signs and symptoms such as physical,mental and psychiatric problems. The cause of MS is not just yet clear but the underlying cause for it is to be either destruction by the immune system or failure of myelin- producing cells. It also includes genetics and environmental factors such as infections. MS have no cure for

The first case of multiple sclerosis (MS) was found in 1849. This disease is not contagious, but epidemiologists have identified some factor such as gender, generics, age, geography and ethnic background that may help determine what cause this disease. MS affects more than 2.3 million people worldwide of those women are more likely than men and people who lives in the north. The average age for women are between 20 to 60 years old. It is important to know that the multiple sclerosis does not have cure and is a chronic

As we already know, Multiple Sclerosis is characterized by demyelinated regions known as plaques/lesions. It is a combination of patient’s history, neurological exam and para-clinical evidence such as MRI, evoked potentials and spinal tap that will allow a physician to come to the diagnosis. Evoked potential tests include VEP, BAEP'S, and SSEP'S. It is a painless procedure where electrodes are placed on the head and body.(14) ‘Response is recorded to determine where delays in nerve transmission occur.’ (14) This is a way of measuring where the demyelination has occurred. A physician will generally perform an eye examination especially if the patients is suffering from balance difficulties or eye strain. (14) ‘Optical coherence tomography (OCT)