Common Obstructive Lung Diseases That Affects Adults And Children

1139 Words Feb 22nd, 2016 5 Pages
Asthma is one of the common obstructive lung diseases that affects adults and children. According to centers of diseases control, approximately 26.8 million people are suffering from asthma []. Asthma is hard to diagnose in early stages because it doesn’t have obvious early symptoms. Studies revealed that inflammatory cells increase in the small airways causing dysfunction in the respiratory system, often before the onset of symptoms or changes in spirometry or imaging[1]. Despite the importance of small airways in respiratory system evaluation, but they are hard to study with the currently available tools [1, 2]. Spirometry has been used for decades as the gold standard pulmonary function test. It requires a series of maneuvers that dependent of patient effort, which is a major limitation of spirometry[3]. Another major limitation of spirometry is the insensitivity for measuring the Forced Expiratory Flow (FEF), both limitation makes spirometry is an insensitive tool to evaluate small airways obstruction [1, 2]. Then, Forced Oscillation Technique (FOT) became available in the market to measures respiratory system impedance. Several studies have shown that Forced Oscillation Technique (FOT) to be a reliable measurement tool to distinguish between healthy lung function and pulmonary lung disease [4-7]. Although, FOT shows promising results in evaluating small airways obstruction but it has been poorly studied as a tool to track hourly temporal variation in…
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