Comparing Methadone And Suboxone Maintenance Treatment

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There were no Cochrane meta-analyses or systematic reviews for comparing methadone and Suboxone maintenance treatment head-to-head. There were 8 trials that had specific populations or were under-powered that I had difficulty choosing between. Before I tried deciding between these articles, I chose to search Medline for any more leads. After searching Medline, I found a rapid response report by the Canadian Agency for Drugs and Technologies in Health that compared Suboxone and methadone head-to-head. After looking into this review more, many of the trials I was considering choosing from Cochrane were included in the study, such as one by McKeganey, Russell, Cockayne (2013) which compared methadone and Suboxone in context of opioid…show more content…
Because I wanted to avoid studies that specifically looked at opioid addiction in context of chronic pain management, I decided to extend my search to PsychINFO. PsychINFO provided me with my second article, a retrospective study that compared effectiveness of methadone, Subutex, and Suboxone head-to-head. When I widened my search terms, on PsychINFO the list was cumbersome and none addressed my topic specifically. It’s also notable that when going through trials from Cochrane, Medline, and PsychINFO, I examined pertinent articles with buprenorphine in the title because some articles refer to Suboxone (buprenorphine-naloxone) as buprenorphine. Results Study 1 Proctor, S.L., Copeland, A.L., Kopak, A.M., Herschman, P.L., Polukhina, N. (2014). A Naturalistic Comparison of the Effectiveness of Methadone and Two Sublingual Formulations of Buprenorphine on Maintenance Treatment Outcomes: Findings From a Retrospective Multisite Study. Experimental and Clinical Psychopharmacology, 22(5), 424-433. Doi: 10.1037/a0037550 Objective: This study compared the effectiveness of methadone, Subutex, and Suboxone in reducing illicit drug use during treatment for opioid dependency and retaining patients for the duration of treatment. Methods: This study was a retrospective study that used patient information from 34 maintenance treatment facilities of the CRC Health Group Inc. in the United States from July 1, 2012 to July 1, 2013. 8,442 patients
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