Creatine Analysis

Creatine allows for increased storage of ATP. “The transfer of a molecule of phosphorous from creatine phosphate to adenosine diphosphate(ADP) results in the formation of ATP. …since the muscle creatine phosphate concentrations can fall to almost zero, it(creatine consumption) can make a significant contribution to the energy supply needed for brief bursts of very high-intensity exercise,” says Dr. Bolotte. The equation for the synthesis of ATP from creatine phosphate and ADP is as follows: PCr + ADP forms ATP + Cr. (http://www.lsms.org/journal/98creat.html) Also, lactic acid levels, which cause muscles to burn during workouts, are lowered by the consumption of creatine. Without the burning sensation, athletes don’t feel the need to stop exercising. Athletes begin their creatine process with a loading phase of twenty grams per day for five days. Then, they consume three to five grams per day. (http://www.mothernature.com/ency/supp/creatine_monohydrate.asp) Many studies have exhibited gains after this process of consumption.

Creatine has many drug like uses and people who are oblivious to creatine would think it is a steroid unless told differently. Creatine can be used as a way of cheating and can be abused to a very dangerous level therefore making it a risk for the athlete. Although creatine is a natural substance, supplementing creatine can boost your creatine level by over 500 times. Creatine can be found in red meat but to get 5 grams of creatine which is the recommended dosage you would have to eat 5kg of raw red

Creatine phosphate has been heavily experimented upon to show that it is an important effector towards muscle activity. When creatine phosphate is present in a solution containing muscle fibers without the presence of ATP, it serves as the energy supplier due to the fact that it absorbs bound adenine nucleotide, which is firmly linked to the contractile elements on muscle fibers (Bozler, 1953). Even in low concentrations this nucleotide can be considered an energy transfer mechanism, for it takes full advantage of the creatine phosphates energy supply, thus acting as a substrate for the enzymatic activity of the contractile elements of a muscle group. Consumption of this nucleotide leads to an increase in the strength of contraction. Creatine phosphate also speeds up rate of relaxation of muscles, for it induces the relaxing effect of ATP (Bozler, 1953). Thus, this research suggests that creatine phosphate is directly linked to instigate muscle contractibility.

     How does Creatine work? When somebody is exercising, his or her muscles demand energy. The energy that the muscle gets is called adenosine triphosphate (ATP). As the muscles keep contracting, the ATP is turned into adenosine diphosphate (ADP). ADP causes your muscles to fatigue. Creatine Phosphate helps to convert ADP into ATP when the ATP is gone. In doing this, the athlete has better endurance during his of her workout or event.

Although creatine is fairly expensive (fifty dollars for a one month supply), the original results of creatine testing and usage were very positive. Creatine supplementation helps the body by increasing the amount of creatine in the muscles, thus enabli ng the body to put out more energy more quickly. It was first discovered in the early 1900s, before creatine supplements were available, that increasing dietary creatine in turn increases the amount of creatine in the muscles (Jenkins). Supplementation of creatine in the diet leads to even higher levels of muscular creatine. Research has confirmed this. Current data indicate that muscle creatine levels increase, on average, 20% after six days of creatine supplementation at twenty grams per day (Eichne r 76). This increase of creatine in the muscles in turn increases the body's potential for exertion. Once creatine supplements were tested in humans, those increases were

Creatine is perhaps the best supplement ever to hit the sports nutrition market. Creatine is a

Creatine (Cr) is a popular dietary supplement used by athletes to increase sports performance, muscle mass, and strength. Creatine was first discovered in “1835, when a French scientist reported finding this constituent of meat” (Demant & Rhodes, 1999). This organic compound is manufactured endogenously by the liver and kidneys “from the amino acids glycine, arginine and methionine” for energy stipulation during muscular contraction. (Arazi, Rahmaninia, Hoseini, & Asadi, 2011). Creatine is either converted into free form Cr or phosphorylated form as known as creatine phosphate (CP). The endogenous production and exogenous consumption of Cr yields about 1 gram a day for the average person (Cooper, Naclerio, Allfrove , & Jimenez, 2012). In

They measured muscular strength and anaerobic performance in trained athletes. 17 physically, active young men were selected for the study and the creatine group had 8 people and the placebo group had 9 people with average age of 23 and 26, respectively. The creatine group took 20 grams a day over the course of 4 servings and the placebo group received a carbohydrate mixture and both groups took it before meals. They trained on day 1 and 4, which included exercises that the whole body. They measured anaerobic power on a 30 second Wingate test, max bench press and squat, took blood and urine samples, and measured height, weight, and body fat. Using an ANOVA with repeated measures across time, the results demonstrated that there was an increase in anaerobic force (12%) and back squat quality (11%) when contrasted with the placebo group. With more creatine in the body than with the control group and the creatine group had lower body fat but more body weight because of increased muscle mass. Proper training and creatine led to power and force increases for these athletes, which is helpful to a running back in improving power, speed, and game

From a very early age sports are introduced upon both young boys and girls. Although it begins with sportsmanship and teamwork, it begins to evolve into new objectives when these young athletes enter high school. In fact, high school sports are vastly different. Your mind is trained to obliterate the opponent and win at all costs. This mentality can often lead many young athletes to turn to supplements to assist in muscle building. The most common supplement in use currently is Creatine. While athletic departments and sports nutrition stores claim that it is harmless, why do so many high school athletes end up with severe muscular and pulmonary damage? The answer has yet to be clearly

Periodized heavy resistance training was performed for 12 wk. Creatine or placebo capsules were consumed 25 grams per day for 1 wk followed by a maintenance dose of 5 grams per day for the remainder of the training. RESULTS: After 12 wk, significant increases in body mass and fat-free mass were greater in creatine than placebo subjects. After 12 wks, increases in bench press and squat were greater in creatine subjects. Compared with placebo subjects, creatine subjects demonstrated significantly greater increases in muscle total, creatine concentrations were unchanged in placebo subjects. Muscle creatine was significantly elevated after 1 wk in creatine subjects (22%), and values remained significantly greater than placebo subjects after 12 wk. Average volume lifted in the bench press during training was significantly greater in creatine subjects during weeks 5-8. No negative side effects to the supplementation were reported. CONCLUSION: Creatine supplementation enhanced fat-free mass, physical performance, and muscle morphology in response to heavy resistance training, presumably mediated via higher quality training sessions. This study was conducted by Richard B. Kreider of the Exercise & Sport Nutrition Laboratory Department of Human Movement Sciences and Education The University of Memphis. The one concern I have with this study is it seemed to leave out the limitations that Creatine may have on some body

But why is creatine supplementation needed for athletic performance if it can be manufactured by the body? Higher levels of creatine before exercise seem to have ergogenic effects which help the body perform better. Whether creatine is useful in long duration aerobic exercise hasn't been proven yet but it has a very specific and distinct function during

The Creatine supplement most commonly used is Creatine Monohydrate (C4H11N3O3). There are other derivatives of this supplement. Creatine Monohydrate has a variety of influences on athletes. Creatine’s occupation is to raise the rate at which ATP (Adenosine Triphosphate) is produced (Creatine Monohydrate Supplementation). When a muscle is used an ATP molecule goes through hydrolysis, the breaking of a chemical bond using H20. The muscle uses this breaking down of ATP to release energy. The ATP gives off an ADP (Adenosine Diphosphate) molecule. Due to the reliability of ATP breaking down with a water molecule, the amount of ATP available in the muscle cells is increased. At the same time ATP is being converted into ADP, ADP is being changed back to ATP inside the muscle. During the contraction of the muscle, the changing back of ADP to ATP is achieved by the Creatine already present in the cells. However, this rebuilding of ATP is not a direct result of the use of the Creatine in the cellular complex. Right upon the taking of Creatine Monohydrate, the total muscular capacity levels of phosphocreatine (PCr) and Creatine Monophosphate increase. This elevation of phosphocreatine “shifts the equilibrium towards the production of ATP,” allowing ATP to be generated at a much faster rate ( Muscle and Strength Magazine). This is the chemistry behind what Creatine does to your body and the reactions

Creatine is the primary metabolic fuel for high intensity, short duration movements such as sprinting, lifting heavy weights, and jumping to maximal heights (Smith-Ryan & Antonio, 2013), and a significant body of research (it is the most extensively studied ergogenic aid) reports supplementation during training can optimize muscle creatine stores, increased high-intensity intermittent work output, and promote greater gains in strength and muscle mass, plus Cr has been demonstrated to provide some therapeutic benefits in clinical populations (Kreider, 2008, p. 430). Cr is also known as methylguanidinoacetic acid, which is an amino acid derived compound chemically classified as a non-protein nitrogen (Smith-Ryan & Antonio, 2013). Cr can be

Creatine monohydrate supplementation has been shown to result in an increase in skeletal muscle total and phosphocreatine concentration, increase fat-free mass, and enhance high-intensity exercise performance in young healthy men and women. Recent evidence has also demonstrated a neuroprotective effect of creatine monohydrate

Creatine helps in increasing speed, power, and size of the muscles, strength endurance and tolerance to fatigue.