Creatine Research Paper

The supplement creatine is used for faster recovery for muscles after short periods of exercise. The theory is an athlete on creatine can exhibit more explosive bursts of energy allowing for longer weight workouts, more sprints, etc. Increased muscle mass and bulk are two of the ideas behind creatine, but they only occur as long as people work out while taking the substance. It doesn’t create

Creatine has many drug like uses and people who are oblivious to creatine would think it is a steroid unless told differently. Creatine can be used as a way of cheating and can be abused to a very dangerous level therefore making it a risk for the athlete. Although creatine is a natural substance, supplementing creatine can boost your creatine level by over 500 times. Creatine can be found in red meat but to get 5 grams of creatine which is the recommended dosage you would have to eat 5kg of raw red

Creatine phosphate has been heavily experimented upon to show that it is an important effector towards muscle activity. When creatine phosphate is present in a solution containing muscle fibers without the presence of ATP, it serves as the energy supplier due to the fact that it absorbs bound adenine nucleotide, which is firmly linked to the contractile elements on muscle fibers (Bozler, 1953). Even in low concentrations this nucleotide can be considered an energy transfer mechanism, for it takes full advantage of the creatine phosphates energy supply, thus acting as a substrate for the enzymatic activity of the contractile elements of a muscle group. Consumption of this nucleotide leads to an increase in the strength of contraction. Creatine phosphate also speeds up rate of relaxation of muscles, for it induces the relaxing effect of ATP (Bozler, 1953). Thus, this research suggests that creatine phosphate is directly linked to instigate muscle contractibility.

Creatine Monohydrate has been proven to significantly enhance athletic performance in the areas of power, strength, and muscle mass. Most importantly though, it doesn't seem to have any serious side effects. Also, since Creatine is found naturally in the body and in foods, it is likely that it will not be removed from sports.      

It is found in skeletal muscles. Creatine phosphate can house high-energy phosphate bonds. There is an abundance of ATP while the muscle cell is at rest. The creatine kinase transfers the high-energy phosphate bonds of the ATP to the high-energy phosphate bonds of the creatine phosphate. Once the cell is ready to contract, creatine kinase removes the phosphate groups from creatine phosphate and transfers them to ADP to create ATP. ATP is used to drive the contraction since it is a quick energy source. A large amount of creatine kinase should not be present in the bloodstream unless there is a large-scale destruction of muscle cells. The Duchenne muscular dystrophy causes this phenomenon to occur where muscle cell membranes are destroyed spilling out the creatine kinase into the bloodstream.

This enzyme causes Creatine Phosphophate (which is also present in the muscle cell) to be broken down into Creatine and Phosphate.

Although creatine is fairly expensive (fifty dollars for a one month supply), the original results of creatine testing and usage were very positive. Creatine supplementation helps the body by increasing the amount of creatine in the muscles, thus enabli ng the body to put out more energy more quickly. It was first discovered in the early 1900s, before creatine supplements were available, that increasing dietary creatine in turn increases the amount of creatine in the muscles (Jenkins). Supplementation of creatine in the diet leads to even higher levels of muscular creatine. Research has confirmed this. Current data indicate that muscle creatine levels increase, on average, 20% after six days of creatine supplementation at twenty grams per day (Eichne r 76). This increase of creatine in the muscles in turn increases the body's potential for exertion. Once creatine supplements were tested in humans, those increases were

A number of studies have examined the effect of creatine supplementation on performance. The consensus appears to be that creatine can increase the amount of work done by 8% in the first few short duration, maximal effort trials. Creatine also helped reduce energy waste. As a result, creatine enhances performance and decreases you muscle fatigue.

Creatine (Cr) is a popular dietary supplement used by athletes to increase sports performance, muscle mass, and strength. Creatine was first discovered in “1835, when a French scientist reported finding this constituent of meat” (Demant & Rhodes, 1999). This organic compound is manufactured endogenously by the liver and kidneys “from the amino acids glycine, arginine and methionine” for energy stipulation during muscular contraction. (Arazi, Rahmaninia, Hoseini, & Asadi, 2011). Creatine is either converted into free form Cr or phosphorylated form as known as creatine phosphate (CP). The endogenous production and exogenous consumption of Cr yields about 1 gram a day for the average person (Cooper, Naclerio, Allfrove , & Jimenez, 2012). In

They measured muscular strength and anaerobic performance in trained athletes. 17 physically, active young men were selected for the study and the creatine group had 8 people and the placebo group had 9 people with average age of 23 and 26, respectively. The creatine group took 20 grams a day over the course of 4 servings and the placebo group received a carbohydrate mixture and both groups took it before meals. They trained on day 1 and 4, which included exercises that the whole body. They measured anaerobic power on a 30 second Wingate test, max bench press and squat, took blood and urine samples, and measured height, weight, and body fat. Using an ANOVA with repeated measures across time, the results demonstrated that there was an increase in anaerobic force (12%) and back squat quality (11%) when contrasted with the placebo group. With more creatine in the body than with the control group and the creatine group had lower body fat but more body weight because of increased muscle mass. Proper training and creatine led to power and force increases for these athletes, which is helpful to a running back in improving power, speed, and game

The Creatine supplement most commonly used is Creatine Monohydrate (C4H11N3O3). There are other derivatives of this supplement. Creatine Monohydrate has a variety of influences on athletes. Creatine’s occupation is to raise the rate at which ATP (Adenosine Triphosphate) is produced (Creatine Monohydrate Supplementation). When a muscle is used an ATP molecule goes through hydrolysis, the breaking of a chemical bond using H20. The muscle uses this breaking down of ATP to release energy. The ATP gives off an ADP (Adenosine Diphosphate) molecule. Due to the reliability of ATP breaking down with a water molecule, the amount of ATP available in the muscle cells is increased. At the same time ATP is being converted into ADP, ADP is being changed back to ATP inside the muscle. During the contraction of the muscle, the changing back of ADP to ATP is achieved by the Creatine already present in the cells. However, this rebuilding of ATP is not a direct result of the use of the Creatine in the cellular complex. Right upon the taking of Creatine Monohydrate, the total muscular capacity levels of phosphocreatine (PCr) and Creatine Monophosphate increase. This elevation of phosphocreatine “shifts the equilibrium towards the production of ATP,” allowing ATP to be generated at a much faster rate ( Muscle and Strength Magazine). This is the chemistry behind what Creatine does to your body and the reactions

Next, Creatine is a supplement made of three different amino acids glycine, arginine, and methionine. Creatine can be produced by the body and found in high protein meats. When creatine enters the body it bonds with a phosphate molecule to form creatine phosphate. When macronutrients are consumed they go through a process called oxidation to become adenosine triphosphate (ATP). ATP is molecule that stores energy. When a task is performed energy is given off to perform the task and a phosphate is lost. Once a phosphate is lost ATP becomes ATD (adenosine diphosphate). ATD is useless to the body and can not be used for energy unless it is formed back into ATP. Creatine gives its phosphate to ATD to make up for the missing phosphate, reforming ATP. Creatine provides more energy to increase performances and strength while training. Shannon Clark, whom holds a degree in exercise science and sport performance said “Creatine allows you to keep pushing hard in the gym at a time when you would previously had to decrease the load or stop entirely, so it helps in building muscle faster” (Clark). Taking a creatine supplement provides more energy needed to build strength.

However; there is no evidence that creatine has any neuroprotective aspects. Continuing to look into clinical supplementation of creatine, it may be beneficial with conditions relating to muscle dysfunction.

Creatine can be beneficial to many people around the world because it improves the health, desires, and overall quality of life. Creatine can increase muscle energy, improve memory in some cases, lose weight, and increase muscle growth.

Creatine helps in increasing speed, power, and size of the muscles, strength endurance and tolerance to fatigue.