Creatine Research Paper

Creatine is a naturally occurring compound that is produced from amino acids by the kidneys and liver. It is also found in foods such as poultry, fish and meat. Creatine monohydrate is produced commercially for use as a supplement. There are benefits of using creatine as a performance enhancing supplement which include; supplying energy to muscles, delay fatigue during short and intense exercises, decrease recovery time between sessions of activities, enhancing the volume of muscles, increase of muscle mass and neutralizing lactic acid build-up. Creatine functions by increasing the amounts of creatine phosphate in the muscles which in turn increases the rate at which ATP can be regenerated from ADP (Marzilli, 2008). This regeneration of ATP leads to decrease in fatigue allowing the muscle to function for a longer period. High levels of ATP decreases dependence on

Creatine is a supplement, creatine is the most popular supplement for improving your performance. Many studies have proven it to be useful for strength, muscle mass and performance. Many people believe it is bad for you and your liver but there are no proven studies showing this if creatine is used correctly. Creatine is a natural substance found inside your muscle cells which helps you gain muscle in several different ways, raise anabolic hormones, boost work load, increase cell hydration, reduce protein break down, lower myostatin levels, improve cell signaling and help strength. Creatine also is 100% legal and is very effective for short term and long term muscle growth. Creatine can also help certain diseases such as Parkinson’s disease and Alzheimer’s. some people believe that creatine should be banned in sports and players caught using creatine should be punished, disqualified, or fined. This includes professional as well as semiprofessional and college athletes. These people believe that both the individual and team use of creatine should be illegal in sports. People who are for creatine believe that when used correctly creatine can be a healthy way to boost your athletic ability in a natural way. They believe creatine should not be banned and that players and teams should be allowed

Creatine phosphate has been heavily experimented upon to show that it is an important effector towards muscle activity. When creatine phosphate is present in a solution containing muscle fibers without the presence of ATP, it serves as the energy supplier due to the fact that it absorbs bound adenine nucleotide, which is firmly linked to the contractile elements on muscle fibers (Bozler, 1953). Even in low concentrations this nucleotide can be considered an energy transfer mechanism, for it takes full advantage of the creatine phosphates energy supply, thus acting as a substrate for the enzymatic activity of the contractile elements of a muscle group. Consumption of this nucleotide leads to an increase in the strength of contraction. Creatine phosphate also speeds up rate of relaxation of muscles, for it induces the relaxing effect of ATP (Bozler, 1953). Thus, this research suggests that creatine phosphate is directly linked to instigate muscle contractibility.

     How does Creatine work? When somebody is exercising, his or her muscles demand energy. The energy that the muscle gets is called adenosine triphosphate (ATP). As the muscles keep contracting, the ATP is turned into adenosine diphosphate (ADP). ADP causes your muscles to fatigue. Creatine Phosphate helps to convert ADP into ATP when the ATP is gone. In doing this, the athlete has better endurance during his of her workout or event.

Although creatine is fairly expensive (fifty dollars for a one month supply), the original results of creatine testing and usage were very positive. Creatine supplementation helps the body by increasing the amount of creatine in the muscles, thus enabli ng the body to put out more energy more quickly. It was first discovered in the early 1900s, before creatine supplements were available, that increasing dietary creatine in turn increases the amount of creatine in the muscles (Jenkins). Supplementation of creatine in the diet leads to even higher levels of muscular creatine. Research has confirmed this. Current data indicate that muscle creatine levels increase, on average, 20% after six days of creatine supplementation at twenty grams per day (Eichne r 76). This increase of creatine in the muscles in turn increases the body's potential for exertion. Once creatine supplements were tested in humans, those increases were

A number of studies have examined the effect of creatine supplementation on performance. The consensus appears to be that creatine can increase the amount of work done by 8% in the first few short duration, maximal effort trials. Creatine also helped reduce energy waste. As a result, creatine enhances performance and decreases you muscle fatigue.

Creatine (Cr) is a popular dietary supplement used by athletes to increase sports performance, muscle mass, and strength. Creatine was first discovered in “1835, when a French scientist reported finding this constituent of meat” (Demant & Rhodes, 1999). This organic compound is manufactured endogenously by the liver and kidneys “from the amino acids glycine, arginine and methionine” for energy stipulation during muscular contraction. (Arazi, Rahmaninia, Hoseini, & Asadi, 2011). Creatine is either converted into free form Cr or phosphorylated form as known as creatine phosphate (CP). The endogenous production and exogenous consumption of Cr yields about 1 gram a day for the average person (Cooper, Naclerio, Allfrove , & Jimenez, 2012). In

They measured muscular strength and anaerobic performance in trained athletes. 17 physically, active young men were selected for the study and the creatine group had 8 people and the placebo group had 9 people with average age of 23 and 26, respectively. The creatine group took 20 grams a day over the course of 4 servings and the placebo group received a carbohydrate mixture and both groups took it before meals. They trained on day 1 and 4, which included exercises that the whole body. They measured anaerobic power on a 30 second Wingate test, max bench press and squat, took blood and urine samples, and measured height, weight, and body fat. Using an ANOVA with repeated measures across time, the results demonstrated that there was an increase in anaerobic force (12%) and back squat quality (11%) when contrasted with the placebo group. With more creatine in the body than with the control group and the creatine group had lower body fat but more body weight because of increased muscle mass. Proper training and creatine led to power and force increases for these athletes, which is helpful to a running back in improving power, speed, and game

Periodized heavy resistance training was performed for 12 wk. Creatine or placebo capsules were consumed 25 grams per day for 1 wk followed by a maintenance dose of 5 grams per day for the remainder of the training. RESULTS: After 12 wk, significant increases in body mass and fat-free mass were greater in creatine than placebo subjects. After 12 wks, increases in bench press and squat were greater in creatine subjects. Compared with placebo subjects, creatine subjects demonstrated significantly greater increases in muscle total, creatine concentrations were unchanged in placebo subjects. Muscle creatine was significantly elevated after 1 wk in creatine subjects (22%), and values remained significantly greater than placebo subjects after 12 wk. Average volume lifted in the bench press during training was significantly greater in creatine subjects during weeks 5-8. No negative side effects to the supplementation were reported. CONCLUSION: Creatine supplementation enhanced fat-free mass, physical performance, and muscle morphology in response to heavy resistance training, presumably mediated via higher quality training sessions. This study was conducted by Richard B. Kreider of the Exercise & Sport Nutrition Laboratory Department of Human Movement Sciences and Education The University of Memphis. The one concern I have with this study is it seemed to leave out the limitations that Creatine may have on some body

The Creatine supplement most commonly used is Creatine Monohydrate (C4H11N3O3). There are other derivatives of this supplement. Creatine Monohydrate has a variety of influences on athletes. Creatine’s occupation is to raise the rate at which ATP (Adenosine Triphosphate) is produced (Creatine Monohydrate Supplementation). When a muscle is used an ATP molecule goes through hydrolysis, the breaking of a chemical bond using H20. The muscle uses this breaking down of ATP to release energy. The ATP gives off an ADP (Adenosine Diphosphate) molecule. Due to the reliability of ATP breaking down with a water molecule, the amount of ATP available in the muscle cells is increased. At the same time ATP is being converted into ADP, ADP is being changed back to ATP inside the muscle. During the contraction of the muscle, the changing back of ADP to ATP is achieved by the Creatine already present in the cells. However, this rebuilding of ATP is not a direct result of the use of the Creatine in the cellular complex. Right upon the taking of Creatine Monohydrate, the total muscular capacity levels of phosphocreatine (PCr) and Creatine Monophosphate increase. This elevation of phosphocreatine “shifts the equilibrium towards the production of ATP,” allowing ATP to be generated at a much faster rate ( Muscle and Strength Magazine). This is the chemistry behind what Creatine does to your body and the reactions

Creatine is the primary metabolic fuel for high intensity, short duration movements such as sprinting, lifting heavy weights, and jumping to maximal heights (Smith-Ryan & Antonio, 2013), and a significant body of research (it is the most extensively studied ergogenic aid) reports supplementation during training can optimize muscle creatine stores, increased high-intensity intermittent work output, and promote greater gains in strength and muscle mass, plus Cr has been demonstrated to provide some therapeutic benefits in clinical populations (Kreider, 2008, p. 430). Cr is also known as methylguanidinoacetic acid, which is an amino acid derived compound chemically classified as a non-protein nitrogen (Smith-Ryan & Antonio, 2013). Cr can be

As most examinations have detailed an inrease in muscle mass and diminished fatigability after taking the dose of creatine, whereas the advantages were only for the athletes who are participating in high intensity sports. But for other athletes,

In addition to this, it has been examined as a playing possible therapeutic role in medical conditions. The energy supplied to your body during and after intense exercise is due to phosphocreatine collected in the muscles. Phosphocreatine may influence the amount of energy exerted in high intensity exercise. On top of that, it is assumed that an increase in muscle phosphocreatine, by use of creatine supplement, can increase creatine levels in your body allowing faster adenosine triphosphate (ATP) expenditure during and after high intensity activity. Analytically, consuming creatine while training may lead to greater training integrations because of increased quality and volume of effort. In regards of possible medical exercise, creatine is personally associated with numerous metabolic

Creatine can be beneficial to many people around the world because it improves the health, desires, and overall quality of life. Creatine can increase muscle energy, improve memory in some cases, lose weight, and increase muscle growth.

Over the last decade, thousands of articles have been written about creatine side effects in scientific journals, magazines, newspapers, and on the Internet. The reason for this interest is that creatine supplements have proven to be one of the most effective methods available to increase strength, power, and muscle mass. Moreover, a number of potential therapeutic creatine benefits have been suggested for various patient populations. Despite this impressive body of research, concerns have been raised about the safety of creatine side effects and ethics of athletes taking performance-enhancing nutritional supplements. While a number of very good reviews have been published about creatine side effects in the scientific literature, a significant amount of misinformation has been written about creatine side effects, particularly in the popular media. Additionally, several nutritional supplement companies have attempted to gain market share by perpetuating some of these creatine side effect myths. The result is that people are often confused about the potential creatine benefits and risks of creatine supplements.