Essay on Cystic Fibrosis: A Way of Life

CF is a chronic condition therefore the patients are either seeking medical attention or receiving (sometime involuntarily) a great deal of medical scrutiny and intervention during their lifetime.

Cystic Fibrosis is a genetic disease that causes the body’s lungs to generate a different type of mucus than a non-infected body would. The contaminated lungs will produce mucus that is thick and adhesive which clogs the lungs and leads to an unpleasant and abhorrent lung infection. CF also interferes with the pancreas, disallowing the digestive enzymes from breaking down and absorbing food in the intestine. This can result in low nutrition, feeble growth, excessive sweat production, difficulties in breathing, and sometimes lung disease. When producing extra sweat and mucus, the body loses salt. If too much salt is lost, it can cause abnormal heart rhythms, disturbance of minerals in the blood, and perhaps, shock.

“About 1 in 4,000 children in the United States are born with CF” (Crosta, 2009) and “one in every 3,600 children born in Canada [have] cystic fibrosis” ("Cystic fibrosis Canada," 2011). According to several resources a consensus has formed which proposes that people with northern European ancestry, specifically those that are white, are more likely to be carriers of the disease and thus more at risk of having children with the mutated gene. This risk is even more likely if the other parent of the child is a carrier. Another risk factor for CF is “family history, since the disease is hereditary it increases they likely hood of

Cystic Fibrosis is the most common genetically inherited disease in Australia with one out of every twenty-five people are carriers of the CF gene or similar gene mutations that end in a CF , symptoms of Cystic Fibrosis depend on the level of severity of the gene. Carriers will develop thick and sticky mucus within the lungs, airways, as a result carriers will experience a persistent and difficult cough, breathlessness, the inability to exercise, constant lung infections, inflamed nasal passage is the reason the life expectancy is 25 years of age. The CF gene also has a significant effect on the digestive symptoms such as foul smelling and greasy excretes with strain to excrete, intestinal blockage, the inability to gain weight and constipation.

With regards to the respiratory system, CF patients are required to wear a chest wall oscillator once daily for 30 minutes to mechanically agitate the mucus build up that they would otherwise not be cough up. On top of the “vest” treatment, they also must take anti-inflammatories and antibiotics regularly to prevent infection and inflammation. As for the GI tract, no mechanical treatment is available, so patients must ingest digestive enzyme supplements that the pancreas cannot deliver naturally. In some cases patients develop CF related diabetes, as the pancreas is also responsible for providing the body with insulin to regulate blood sugar concentrations. On top of these treatments, people with CF must boost the amount of calories and salts in their diets to compensate for the malnourishment and for the amount of salt released by the patients

Cystic fibrosis is a life-threatening genetic disease that primarily affects the lungs and digestive system. People who have Cystic Fibrosis have a defective gene that causes the body to produce thick, sticky mucus that clogs the lungs and eventually leads to life-threatening lung infections. It also obstructs the pancreas and stops natural enzymes from helping the body break down food and absorb nutrients. This genetic disease has affected over 70,000 people worldwide including 30,000 in the United States.

Cystic Fibrosis (Mucoviscidosis) is a disease that changes how the body produces sweat, and mucus glands. It causes organs such as the lungs to not function properly, and could be life threatening. Cystic Fibrosis is a genetic disease, and affects around 70,000 people worldwide. Every year a thousand new cases are reported.

Abnormally thick, abundant secretions from mucous glands can lead to a chronic, diffuse, and obstructive pulmonary disorder in almost all patients.

Have you ever heard of cystic fibrosis? If so, do you know what it is? Well, cystic fibrosis is an acquired issue that causes extreme harm to the lungs and digestive framework. Cystic fibrosis influences the cells that deliver bodily fluid, sweat and digestive juices. These discharged liquids are regularly thin and elusive. Be that as it may, in individuals with cystic fibrosis, a damaged quality causes the discharges to end up thick and sticky. Rather than going about as a grease, the emissions attachment up tubes, channels and ways, particularly in the lungs and pancreas. Although, cystic fibrosis requires day by day consideration, individuals with the condition can go to class and work, and have a superior personal satisfaction than in

Cystic fibrosis is a recessive genetic disease caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. This mutation causes problems with the apical membrane CFTR protein which when working to its full potential regulates the sodium and chloride intake in epithelial cells (Eitan Kerem et al. 2005). It affects about 70,000 people in the world and in the UK it is said to affect 1 in every 2,500 children. The disease causes the apical membrane CFTR protein to not be able to transport the sodium and chloride it needs to, this can have a huge effect on multiple organ systems, mainly the respiratory system. The most common clinical problems Cystic Fibrosis causes are pulmonary damage

Cystic fibrosis mainly affects the CFTR gene, located at 7q31.2, or the 3rd region on the long arm of the seventh chromosome. The CFTR gene is responsible for producing the cystic fibrosis transmembrane conductance regulator

This disease is considered as inherited disease mostly among Caucasians, where approximately 1000 new cases are recorded every year. Latinos and American Indians are among the races most likely to acquire CF by genetic characters and less prevalent among African American. Statistics from the health agencies had recorded that there are more than 10 million Americans who have faulty CF gene carriers without them knowing it (Buckingham, 2012). Based on the Changing Epidemiology of Cystic Fibrosis reported by Simmons (1992) in Journal of Pediatrics, he said that from 17,857 patients treated with cystic fibrosis Foundation demonstrated a significant shift in the age distribution of patients. The adult patient population increased and in 1990s the median age range of patients with this disorder is 12.5 years old. Statistics revealed that among the surveyed patients, 90% of those belong to age 12 was diagnosed with CF. Median survival age doubled in later years from age 14 to 28 years. Females are found to have lower median survival age than males. Etiology The main cause of cystic fibrosis is hereditary where a carrier parents may transmit the faulty CFTR to her offspring, whereas if such gene is transferred to the child, the latter has the chance of 25 percent of developing CF. Experts claimed that if the child acquired the faulty CFTR gene from only one parent, say

Cystic fibrosis is an Autosomal Recessive Disorder. The mutation of the Cystic Fibrosis Transmembrane Regulator is what causes Cystic Fibrosis. Normally, in the cells, CFTR protein is a channel that allows cells to release chloride and other ions. In the case of an individual with Cystic Fibrosis, the protein is defective therefore cells do not release the chloride. For that reason, there is a thick, sticky mucus with individual with cystic fibrosis.

Cystic fibrosis (CF) is an autosomal recessively inherited condition that affects approximately 9000 patients in the UK (Rowe et al, 2005). CF is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene (Rowe et al, 2005), resulting in deficiencies in normal ion transport across cell membranes (Mall and Boucher, 2014). Abnormal ion transport causes the sputum to become dehydrated and more viscous (Mall and Boucher, 2014), leading to the airways becoming blocked and a reduction in the efficacy of the mucocilliary escalator at clearing sputum (Cystic Fibrosis Trust, 2011). This can result in the patient’s symptoms of breathlessness and recurrent infections as the sputum

Cystic fibrosis (CF) is a disease of exocrine gland function that involves multiple organ systems but chiefly results in chronic respiratory infections, pancreatic enzyme insufficiency, and associated complications in untreated patients. CF is the major cause of severe chronic respiratory disease in children, and it is an autosomal recessive disorder involving the exocrine glands. According to Bye (2016), this disorder is caused by mutations in the CF transmembrane conductance regulator protein, which normally functions to regulate the transepithelial ion flow critical to maintaining the proper ionic composition and volume of airway surface fluid.