Cystic Fibrosis is one of the most common and fatal genetic diseases in the United States. Cystic Fibrosis is a disease that causes the body to produce a thick, sticky mucus that clogs the lungs. This can lead to infection and blocks in the pancreas, which stops digestive enzymes from reaching the intestine where they are required in order to digest(“Learning About Cystic Fibrosis,” 2013). Cystic Fibrosis can go undiagnosed for a long period of time. For example, Mackenzie Dondanville 11 years old, four years ago, who had been coughing a lot for the previous year and a half. Due to her being physically athletic while competing in soccer, her pediatrician thought her cough and shortness of breath was due to exercise-induced asthma. It wasn't until Mackenzie's prescribed inhaler isn't working, that they realized something more was going on (“Mackenzies Story,”2018). Cystic Fibrosis is a single gene disease, the Cystic Fibrosis Transmembrane Regulator gene is what causes CF, more than 900 mutations of this single gene has been discovered. Every person inherits two CFTR genes, one from each parent. Children who inherit a faulty CFTR gene from each parent will have CF. Children who inherit one faulty CFTR gene and one normal CFTR …show more content…
The Main treatment for someone with lung problems with CF is chest physical therapy, which is also called chest clapping or percussion. CPT is done by pounding your chest and back repeatedly with your hands or device to loosen the mucus from your lungs so that you can cough it up. Exercise is also a choice of a treatment plan, exercised that make you breathe harder can help loosen the mucus in your airways so you can cough it up. Medication can also be used to treat Cystic Fibrosis, your doctor may prescribe antibiotics, anti-inflammatory medicines, bronchodilators, or other medication that can help clear the mucus buildup in the lungs(“Cystic
Cystic fibrosis affects many of the body’s systems this includes the lungs and digestion. If you have CF your mucus becomes thick and sticky. It builds up in your lungs and blocks your airways. The mucus blocks the air passages in the lungs and creates bacteria. Numerous infections and blockages can cause permanent lung damage and death. Sticky mucus can also block tubes or ducts in
Cystic fibrosis (CF) is an inherited autosomal recessive disorder that affects the lungs and digestive system most often. In the United States some 30,000 children and adults have CF. There are approximately 1,000 new cases of cystic fibrosis diagnosed each year in the US with 70% of patients diagnosed with CF by the age of two, 40% of patients with CF are 18 or older. In the 1950's most children with CF did not survive to attend elementary school, but in 2006 the median age of survival was 37 years (Cystic Fibrosis Foundation, 2007).
Cystic fibrosis (CF) is a serious disease that is life-threatening. This disease is characterized by the buildup of thick mucous in the lungs due to a defective gene within the body. It is a disease that is genetic which means that it is passed down from one’s parents. The disease is genetic because patients with Cystic Fibrosis inherit a defective gene on chromosome 7. This gene is responsible for protein production and the moving of water and salt in and out of the body’s cells. If a person inherits on faulty CF gene from each parent the chances are very high that they will develop Cystic Fibrosis. If the person inherits only one faulty gene from their parents and one normal gene they are known as carriers of CF and usually develop no symptoms of the disease and usually end up living normal lives. However they can pass the faulty gene down to their children.
Cystic fibrosis is a rare, genetic, incurable disease. It affects cells that produce mucus, sweat, and digestive juices, it cause them to be thick and sticky, blocking airways, tubes, ducts, and passageways. The severity of symptoms depends on the person. Common include, cough, shortness of breath, wheezing, exercise intolerance, lung infections(pneumonia and bronchitis), inflamed nasal passages, stuff nose, inability to gain weight and grow, excessive salt in sweat, and foul-smelling, fatty stools, and severe constipation. Diagnostic tests for CF include a screening at birth(blood test), a sweat test(levels of salt), and a genetic test(chromosome 7). Cystic fibrosis is particularly abundant in European-Americans. It is also the most common in the United States. More than 75% of people with CF were diagnosed by age 2. Men and women are both equally affected. Over 30,000 people are living with CF in the United States, and over 70,000 worldwide. Between one and two people die everyday due to cystic fibrosis. The hope is for CF to become less prevalent due to the finding of a cure.
But because the type/severity of cystic fibrosis can differ from one person to another by a lot, there isn’t any normal treatment plan. One common treatment therapy is airway clearance, in which the affected person wears a vest that vibrates at a high frequency, which loosens and thins the mucus buildup. Another is the usage of inhaled medicines. These medicines help open airways and thin the mucus buildup. The medicines are liquids that are made into a mist and inhaled through a nebulizer. The medicines have antibiotics to help fight lung infections. Also, there are pancreatic enzyme capsules, which help improve the absorption of vital nutrients, and are normally taken with most meals and snacks. In addition to the capsule, people with the disease usually take multivitamins. Two relatively new treatments are a type of drug called a CTFR modulator, which targets the defective CTFR gene. These drugs were only recently approved by the FDA, the first was in 2012, and the second just this year (2015). It is expected that the new drugs could add many years to the lives of people affected by Cystic fibrosis. Also, a cystic fibrosis specialist can treat you. The U.S has about 100 cystic fibrosis care centers, which have teams of doctors/nurses and respiratory/physical therapists who all specialize in Cystic fibrosis care/treatment.
Cystic fibrosis is an inherited disorder that affects many functions of the body: breathing, digestion, and reproduction. The lifelong illness usually gets more severe with age and can affect both males and female equally. The symptoms and severity of cystic fibrosis differ from person to person. Most patients have both respiratory and digestive problems, while others only have respiratory problems. Intelligence is not affected in people with CF.
Cystic Fibrosis (CF) is an inherited disease of the secretory gland. Secretory glands that make mucus and sweat. People who have CF inherit two faulty genes one from each other parent the parents do not have the disease. CF affects the lungs, pancreas, liver, and sex organs. In CF, a defect (mutation) in a gene changes a protein that regulates the movement of salt in and out of the cells. The result is thick, sticky mucus in the respiratory, digestive and reproductive systems, and increased salt in sweat. Signs of CF vary, depending the severity of the disease. In the same person they might worsen or get better. The symptoms of CF is persistent cough (having mucus), wheezing, breathlessness, exercise intolerance, repeated lung infections, and
Cystic fibrosis is an autosomal recessive disease which means that it is necessary to have two copies of altered gene to have the disorder.
This paper is over cystic fibrosis (CF). This is the most common life threatening condition in the white population. In the United States there are about 30,000 people who are living with CF and there are approximately 1,000 new cases diagnosed each year. Nearly half of the CF population is 18 years or older and with new breakthroughs in treatments people with CF are able to live longer lives, with the median age now being 40 years old. CF was first described in the 1930s as a distinct clinical entity, however as early as 1650 there has been several references to infants and children with meconium ileus and characteristics of pancreatic and lung disease. Over the years there are have been many improvements in treatments, but people with CF are not always compliant with their therapies. Mostly because they tend to time consuming. In this paper we will discuss what CF is, the diagnosis, treatment options, and prognosis.
Cystic Fibrosis (CF) is a disease that causes problems within the lungs and digestive systems (pancreas, liver, and intestines). It occurs due to the abnormal transport of chloride and sodium across cells leading to excessive secretion of thick mucus in these two major areas of the body. This makes breathing difficult as the thick, sticky mucus clogs the airway, and it can also result in sinus infections, poor growth, infertility, and reduced life expectancy. However, these can sometimes be treated with antibiotics and other medication, like medicated inhalers. It is an autosomal recessive genetic disorder and is caused by one of many different mutations in the gene for the protein cystic fibrosis transmembrane conductance regulator (CFTR)’ . Because CF is the result of an inherited genetic mutation it can therefore be treated with manipulations such as Selective Breeding and Gene Therapy.
Cystic fibrosis is an inherited disease that ultimately leads to death. It affects every racial group worldwide, but its prevalence varies from country to country. In those with cystic fibrosis, the lungs and digestive system are primarily affected by the disease. With the new developments in treatment and management, the 50 percent survival rate from the 1970’s has greatly improved, allowing patients to continue to live their lives longer than ever expected in the past. The new developments in prevention of exacerbations, therapy drugs and methods to preserve lung function have done great things to help patients extend their lives. Education is another important aspect of treating cystic fibrosis. For example, more the
Cystic fibrosis, a genetic disease that limits one’s ability to breathe, affects mostly the lungs but also can have a damaging effect on the intestine, kidneys, liver, and pancreas. The name cystic fibrosis comes from the characteristic fibrosis and cysts that form within the pancreas. It is a life-threatening illness, which afflicts around 30,000 people in the United States and about 70,000 worldwide, with approximately 1,000 new cases being diagnosed each year and more than 75 percent of those people being diagnosed by the age of two. Nearly half of the cystic fibrosis population is over 18 years of age, and the life expectancy is between 37 to 50 years old. The ailment, commonly referred to as CF, is a recessive disease, so both
Cystic fibrosis (CF) is a multisystem disease: the major clinical manifestations are related to respiratory disease. Clinical manifestations of CF are retention of sputum, reduced exercise capacity, and breathlessness. Physical therapy involves a range of interventions (e.g. airway clearance, physical therapy), which have an overall aim of reducing progression of CF.
Cystic Fibrosis (CF) is a disorder that is passed down from parent to child, which primarily occurs in the Secretory gland, this is the part of the human body that produces mucus. This by all mean does not indicate that the parents are affected, but instead states that they are carriers of this disorder. This is the reason why CF is said to be a recessive trait as oppose to a dominant trait. The main affected areas of the human body by this disorder are the lungs, pancreas, liver, intestines, sinuses, and the female and male reproductive organs according to (Cystic Fibrosis… 2015). When an individual has Cystic Fibrosis the buildup of mucus occurs
Cystic Fibrosis, a very serious inherited genetic disease, is also known as CF and sixty-five roses. This disease affects one in every 3,000 live births. It may first appear in a newborn, but can appear all the way up until a young adult. However, ten percent of most cases are apparent at birth. CF affects the lungs and causes a build-up of abnormally thick mucus which leads to chest infections, and CF also affects the reproductive system. Doctors do not know what causes the mucus to thicken. CF’s infections usually lead to death in childhood and early adulthood. Most people infected with CF had a life span into their teens long ago. Now, due to advanced technology, the life span is in the fifties or older.