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Demyelination Case Study

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Demyelination occurs during inflammatory phases.
Axons and oligodendrocytes in the CNS undergo demyelination. thymus gland involution is associated with MS, reduced thymus output disturb the homeostasis of Peripheral naïve CD4 T cells, that will produce an autoimmune response against myelin
• AS a result the nerve conduction from and to the brain will be distorted, slowed, and interrupted.
• Symptoms such as blindness, paralysis and numbness that worsen during the attack or relapse are caused by delayed synaptic transmission and increased conduction block.

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