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Dermographism: Concomitant Thyroid Disease

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Case # 2 Dermographism Abstract: Dermographism or skin writing is a condition which occurs mostly in young adults who are otherwise healthy. Occasionally these patients have concomitant thyroid disease. Dermographism is accentuated by stress. Weals can occur by minor pressure, kissing, after hot shower or bath,rubbing or exercise. It is hypothesized to have co –relation with H. pylori infection. The course of dermographism can be prolonged to months to years. However, after a period of time it gradually improves with no significant symptoms. History: 35 years old lady presented with a history of hives that itch. Patient informed of having raised bumpy weals on skin after rubbing or applying pressure . Patient noticed these bumpy hives will remain for less than 1 hour then disappear. She is a known case …show more content…

However, ESR, thyroid antibodies, T3, T4, TSH,FBC, LFT’s ANA, Complement screen for C1 esteraseinhibitor, stool analysis for parasites, urinanalysis for bacteria, H. Pylori screening and skin biopsy for uticarial vasculitis can be ordered. Treatment: Usually no treatment is required other than councelling for dermographism. Since the patient ‘s condition was bothersome hence she was prescribed cetirizine(zyrtec) to giver her relief. Advice was given on avoiding hot bath or shower, rough towelling or clothing against her skin. Discussion: Dermographism is reported to occur in 25% -50% of healthy population among which 5% are symptomatic. Histamine is most likely a mediator, other mast cells such as prostaglandins, leukotrienes, platelet activating factor, serotonin , chemotactic factors are not directly related. It has been hypothesized that the IgE-sensitized mast cells can react to unknown antigen which is induced by skin stroking. H.Pylori have an etiologic role in dermographism.

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