Designing a Malaria Intervention Supply Chain: a Case Study

Ecological factors that encourage the Anopheles mosquito, and thus also encourage the prevalence of malaria include: being near the equator, densely populated areas, warmer temperatures, standing water, maintaining water for irrigation and deforested areas. (Holy p.1)

About 1,500 cases of malaria are diagnosed in the United States annually, mostly in returned travelers” (Global Health - Division of Parasitic Diseases , 2010). Malaria risk is not distributed homogeneously throughout all countries. Some destinations have malaria transmission occurring throughout the whole country, while in others it occurs in defined pockets so the traveler should be weary of areas whose climate is conducive to mosquitoes.

Also, a malaria surveillance and response program was implemented to insure urgency in attacking this

Malaria (also called biduoterian fever, blackwater fever, falciparum malaria, plasmodium, Quartan malaria, and tertian malaria) is one of the most infectious and most common diseases in the world. This serious, sometimes-fatal disease is caused by a parasite that is carried by a certain species of mosquito called the Anopheles. It claims more lives every year than any other transmissible disease except tuberculosis. Every year, five hundred million adults and children (around nine percent of the world’s population) contract the disease and of these, one hundred million people die. Children are more susceptible to the disease than adults, and in Africa, where ninety percent of the world’s cases occur and where eighty percent of the cases

Background - Malaria is a water borne disease. It is spread by a parasite-carrying mosquito. It kills many people and reduces a country 's capacity to develop. There are different strategies to combat malaria. Around half the population is at risk of malaria and this disease is active in 106 counties across Africa, Asian and the Americas (see source 3). the global annual mortality from malaria is between 1.5 - 3 million deaths, or between 4000 and 8000 each day. Developing countries are most vulnerable to Malaria and as shown on source 2 Malaria has been spread across many various other countries including in Europe, but these countries have eradicated Malaria.

Malaria is a serious and sometimes fatal disease caused by a parasite that commonly infects a certain type of mosquito which feeds on humans. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness.. In 2015 an estimated 212 million cases of malaria occurred worldwide and 429,000 people died, mostly children in the African Region. Although malaria can be a deadly disease, illness and death from malaria can usually be prevented. In Malawi, malaria is very common because

Moreover, when examining the intersection between the medical impacts of malaria on the human and the social consequences, a vicious cycle is revealed in which the body, the community, and the economy are all similarly impacted by the presence of malaria in a

Malaria has been a huge problem among many developing nations over the past century. The amount of people in the entire world that die from malaria each year is between 700,000 and 2.7 million. 75% of these deaths are African children (Med. Letter on CDC & FDA, 2001). 90% of the malaria cases in the world are located in Sub-Saharan Africa. Once again, the majority of these deaths are of children (Randerson, 2002). The numbers speak for themselves. Malaria is a huge problem and needs to be dealt with immediately.

Also, human population movement from higher transmission areas jeopardizes reintroduction and resurgence in malaria-free regions, and in addition has undermined elimination works in the past. For that reason, it is important to understand the patterns of parasite dispersal in order to target control by pinpointing regions where the imported infections originate from and where they play a part in transmission.

Malaria is considered one of the most serious and life-threatening public health problems in the world. According to World Health Organization, more than 3 billion people live in areas classified as being at risk from malaria, with nearly 200 million cases.1 Approximately, 750,000 deaths occur every year, primarily among children, due to malaria and its complications.1 Children less than 5 years of age are more vulnerable to be affected by malaria.2 In 2015, about 438,000 malaria deaths were reported, of which estimated 69% were children under 5 years of age.2

Plasmodium a single-cell parasitic protozoa is transmitted to humans via the bite of an infected female Anopheles species mosquitoes. This can lead to potentially fatal parasites, rapidly multiplying in the liver attacking red blood cells resulting in symptoms arising from cycles of fevers, chills, severe headaches, vomiting, jaundice and diarrhoea. One major disastrous symptom includes sweats accompanied by anaemia, cause damages to vital organs and interruption of blood supply to the brain, which could result in incurable illness leading to fatal death. In very severe cases it can cause seizures, comas or even death. Symptoms usually present between ten to fifteen days after the initial infection. Unlike other diseases, Malaria can represent in people months or even years later. Death rate is approximately 1%-5% due to the spread of Malaria in Afghanistan, affecting each and everyone.

Malaria is the world’s most deadly infectious disease by numbers and disproportionately effects tropical third-world populations which are ill-equipped to handle it. Each year hundreds of thousands of lives are lost to Malaria and more than one-million more are disabled or lose productivity due to symptoms. Current malaria prevention efforts are focused on Insecticide Treated Nets (ITN’s) and Indoor Residual Spraying (IRS) tactics. Currently, there is not sufficient data which supports one prevention method as more effective than the other. Recent malaria statistics were used to create a mathematical model for determining the most effective prevention method. The model plotted expected

Malaria has to potential to effect nearly 3.5 billion people. There are many options for some protection against contracting malaria such as mosquito nets and insecticide sprays, however, because of poor living environments and even lack of education on how to protect themselves, the spread of malaria continued.

About 3.3 billion people, that is about half of the world’s population are at risk of contracting malaria (figure 1). Every year there are 250 million cases of malaria, and nearly 1 million deaths. That amounts to 2,732 deaths per day. Out of those million people that die every year, 800,000 of them are African children under the age of 5. To control malaria three actions need to be taken: insecticides need to be used to decrease the vector population, people have to be educated as to how to prevent the vector from reproducing, and anti-malarial drugs need to be distributed. To understand the vector and what the vector is, scientists had to first discover what the parasite was and how it worked. It was not until the year 1880 that French Physician Charles Laveran discovered that Malaria was caused by a protozoan in the genus Plasmodium (Malaria, 2013)

Malaria is one of the ten most common, yet deadly diseases in the world. It is a parasitic disease spread by the bite of Anopheles mosquito, which is active between dusk and dawn. Malaria occurs in over 100 countries and territories.