3.6 Interferences study The influence of various substances as compounds potentially interfering with the determination of risperidone was studied under optimum conditions with 300.0 μM risperidone at pH 7.0. The potentially interfering substances were determined from the group of substances commonly detected with risperidone in pharmaceuticals. The tolerance limit was specified as the maximum concentration of the interfering substance that caused an error of less than ±5% in the measurement of risperidone. According to the results, neither a 1000-fold excess of methanol, ethanol, NH4 +, Fe2+, Fe3+, Mg2+, Fe2+, Fe3+, SO42−, Al3+, SO42−NH4 +, Fe2+, Fe3+, CO32−, Cl− or F−, CO32−, alanine, phenylalanine did not affect the selectivity, nor a 50-fold excess of levodopa, carbidopa, methyldopa, epinephrine, norepinephrine and methylphenidate interfered with the determination of risperidone. …show more content…
The results for determination of the risperidone and methylphenidate in Risperidone tablet and Ritalin tablet are presented in Table 1. Satisfactory recoveries of the experimental results were determined for risperidone and methylphenidate. The repeatability of the method was indicated by the mean relative standard deviation
In this day and age, drugs are being prescribed without hesitation. In fact, many of these drugs are being prescribed for children with various disorders. One of these disorders is called Attention Deficit Hyperactivity Disorder (ADHD). An estimated five to ten percent of children are diagnosed with this syndrome (Taylor 11). One of the methods to treat this disorder is to use stimulants, specifically Ritalin. This method is controversial because it has many side effects and its long-term effects are unknown. It can also lead to addiction. Approximately two to three percent of elementary school children are taking some kind of stimulant to treat ADHD (Taylor 64). Since so many children are taking this medication, new problems have arisen.
Physiological Changes Due to Risperdal Hallucinations, delusions, paranoia, psychosis and thought disorder are all symptoms of Schizophrenia and people who suffer from these symptoms seek the treatment of atypical anti-psychotic medications. Those medicines include Risperidone (Risperdal), Clozapine (Clozaril) , Ziprasidone (Geodon) and Quetiapine(Seroquel). The purpose of these medications is to alleviate symptoms of Schizophrenia and lessen the chances of a recurrence. The basic function of Atypical Antipsychotics is to reduce the effects of blockage in the dopamine receptors and serotonin and allow communication between nerve cells. Dopamine is thought to be relevant in Schizophrenic symptoms and
Discussion: Mrs. Lanchance reported that Dylan Risperdal was D/c'd and Cogentin was prescribed. Mrs.Lanchace said that she has noticed some changes in behavior since the change in meds. She stated the Dylan is "edgy, hyperactive and easily distracted." She also informed the team that the MRI test for an ocular headache came out normal and no further test was recommended.
Garber, Stephen W., Ph.D, Marianne Daniels Garber, Ph.D, and Robyn Freedman Spizman. Beyond Ritalin. New York: Villard, 1996. p 56-59.
There are two groups of stimulants: methylphenidate-based medications, which include Ritalin, Concerta, and Metadate, and dextroamphetamine-based medications, which include Adderall, Vyvanse, and Dexedrine (Boorady 2). The two most popular of these groups, Ritalin and Adderall, have these similar side effects: loss of appetite, insomnia, dizziness, nervousness, and prone to raising blood pressure (Ogbru 1). Both of these medications are also similar in short-acting and long-acting formulations, but, according to Susan York Morris, Ritalin is highly preferred over Adderall because it reaches its performance peak much more quickly, and prevents cells from reabsorbing norepinephrines, a precursor of adrenaline (Marcovitch 476), and dopamine, a precursor of norepinephrines that conveys inhibitory in the neurological system (Marcovitch 197), keeping them active in the brain.. (Morris 2). As a child, my parents began the process of testing different medications to treat my ADHD, and they began with Ritalin because it received the majority of positive results. Unfortunately, after random spurts of aggression, irritability, and unrest, they had to try a different medication. Next, they tested Adderall, but the same results occurred, but at greater rates than the
risperidone whereas in this one there was a fixed dose to limit breach in blinding and to facilitate comparison between similar groups, also having this fixed dosage helped prevent bias because when using a titrating schedule of dosing in a randomized trial, it tends to show bias toward a desired goal. Risperidone in this study was well tolerated and there weren’t significant differences in weight gain or sedation(13). One of the main things disliked about risperidone is its tendency to increase the incidence of dyskinesia and other extrapyramidal side effects. In this study only mild and transient dyskinesias were seen in only 3 children, however that could be due to the low fixed dosage(13) of the study.
Risperidone is atypical antipsychotics drug used in the treatment of mental and mood disorders. It is helping to restore the balance of certain natural substances in the brain. This medication may also be used in combination
There are many medications that affect children’s health in today’s society. Doctors prescribe lots of medication which can be avoided, when children are properly diagnosed with certain health problems. Attention - deficit/hyperactivity disorder (ADHD) has impacted many people with the danger of certain medications which is overprescribed to all ages each year. The hidden dangers of the medications these doctors are prescribing, is that our children are being misdiagnosed with ADHD at a very early age, and this is causing many different side effects. Long term use of these medications can cause severe side effects. The most commonly prescribed drugs, are Ritalin, Adderall and Concerta, which cause children to have nervousness, appetite suppression, insomnia and increased blood pressure and heart problems. Also pharmaceutical companies are well aware of the danger to children and adults that these drugs may cause.
Furthermore, The tone of the article is persuasive with medical professional quoting, and statics depicted, to convince the audience, mainly parents that the use of internet is no longer normal but on the path of becoming a recognised diagnosis. IF the article succeeds in its aim, then parents with children with similar symptoms will treat the diagnosis with stimulants, antidepressants and psychiatric drugs despite the limited research and lack of comprehensive clinical practice guidelines (Rivers, 2009). Psychotropic medication seems to be prescribed as the first pioririty, furthermore it is more convenient for many families who live with low-socioeconomic lifestyles, because of the time and money advantage. Sessions, Overseas data and anecdotal
1. Brodaty, H., Ames, D., Snowdon, J., Woodward, M., Kirwan, J., Clarnette, R., & ... Greenspan, D. (2005). Risperidone for psychosis of Alzheimer's disease and mixed dementia: results of a double-blind, placebo-controlled trial. International Journal of Geriatric Psychiatry, 20(12), 1153-1157.
Ritalin is another example of a prescription ADHD stimulant that is misused frequently with a high mortality rate from overdose. Ritalin, which is more prevalent with high school age students, is primarily misused for weight loss and a feeling being high. The majority of children misusing prescription drugs such a Ritalin are under the impression that it is safer then illegal street drugs (CCHR, 2013). Ritalin is the most common stimulant drug prescribed to children with ADHD, but is also prescribed for other disorders, such as cancer, brain injury and pain management (Morton & Stockton, 2000). According to Morton & Stockton (2000) the effects of Ritalin are similar to the feeling of using cocaine, which may be one of the reasons that the ADHD drug is misused. According to research done by Musser et al. (1998) most school aged children using Ritalin did not think that Ritalin or any other prescription medication for ADHD could be abused. This ignorance may be part of the overwhelming reason that drugs such as Ritalin are becoming more widely
Antipsychotics are classified as major tranquilizers that are used to treat mental health illnesses such as schizophrenia, bipolar disorder, and other mental illnesses. They can also treat severe depression and severe anxiety. These antipsychotics drugs reduce or increase the effect of neurotransmitters in the brain to regulate levels that help transfer information throughout the brain. The neurotransmitters that are affected are the serotonin, dopamine, and noradrenaline.
Were considered to be prevalent users. The theoretical duration of use of each prescription was calculated using information about the dispensing date, the number of units dispensed and the prescribed dosage regimen. Discontinuation of ADHD treatment was defined as not having
Many individuals may assume that it has a better safety profile due to the agent not being a controlled substance, and efficacy still remains questioned (Mohammadi & Akhondzadeh, 2007). In the present paper, the similarities and differences between methylphenidate and atomoxetine will be investigated in regards to efficacy and safety. The following literature that is examined supports methylphenidate’s efficacy over the use of atomoxetine. Furthermore, it also supports there are non-significant differences in terms of the safety profiles when the medications are compared.
Those children that are diagnosed with ADHD are usually prescribed psycho-stimulant medications, such as ‘methylphenidate’, otherwise known as ‘Ritalin’, as the primary method of treatment. (Chandler, 2010).