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Developments to Hydrogels Made From 2-Hydroxyethyl Methacrylate

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There have been a significant development in the field of hydrogels made from 2-hydroxyethyl methacrylate (HEMA). HEMA is the monomer of the polymer poly2-hydroxyethylmethacrylate.This polymer has the remarkable property to get swelled due to the molecule’s hydrophilic pendant group when subjected to water. It is capable of absorbing water from 10 to 600% relative to the dry weight. Because of its unique property, it was one of the first material to be used in contact lenses. Xanthan gum is a polysaccharide secreted by the bacterium Xanthomonas campestris. There have been a lot of work done on Xanthan gum (GX), it has very good thickening properties of aqueous salts solutions. These are used as emulsifiers which contain hydrophilic and…show more content…
In particular, a lot of of methods exists to incorporate micrometer to centimeter scale of chemical gradients and complex biomaterials incorporating such gradients[5].

In our study we have used Xanthan Gum, a natural polymer to form hydrogel with HEMA. A hydrogel is a three dimensional cross linked polymeric network formed between a hydrophilic polymer like Xanthan gum and a hydrophobic polymer like HEMA. Here the solution of Xanthan gum and HEMA was cross linked with N,N,N,N-Tetra methylethylenediamine (TEMED) and Ammonium Persulphate (APS). The hydrogels formed from naturally occurring polymers have remarkable use in many biomedical applications like wound healing. These hydrogels show a better response in swelling compared to hydrogels formed from synthetic polymer. They possesses anti microbial properties whereas synthetic matrial based hydrogels need to incorporate antimicrobial agent to comprise antimicrobial property within the hydrogel. Hydrogels made from the naturally occurring polymer of xanthan gum are a type of biomaterial. These polymeric biomaterials have promising applications in drug delivery, tissueengineering, biomedical sensing, skin grafting, medical adhesives and textiles. From a practical perspective, medical applications of polymers fall into three broad categories: (i)extracorporealuses(catheters, tubing, and fluid lines; dialysis membranes/artificial kidney; ocular devices; wound dressings and artificial
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