Diabetes And Drug Treatment Of Diabetes

Diabetes is a disease where the body is unable to produce or use insulin effectively. Insulin is needed for proper storage and use of carbohydrates. Without it, blood sugar levels can become too high or too low, resulting in a diabetic emergency. It affects about 7.8% of the population. The incidence of diabetes is known to increase with age. It’s the leading cause of end-stage renal disease in the US, and is the primary cause of blindness and foot and leg amputation. It is known to cause neuropathy in up to 70% of diabetic patients. Individuals with diabetes are twice as likely to develop cardiovascular disease. There are two types of diabetes: Type 1 and Type 2.

Type 1 diabetes, is an incurable but treatable disease which can occur at any age but is mostly found in children due to the high levels of glucose in the blood (Eckman 2011). Juvenile diabetes affects about 1 in every 400-600 children and more than 13,000 are diagnosed yearly (Couch 2008). Type 1 Diabetes means your blood glucose, or blood sugar, is too high. With Type 1 diabetes, your pancreas does not make insulin. Insulin is a hormone, which helps glucose gets into your cells to provide energy. Without insulin, too much glucose stays in your blood. Over time, high blood glucose can lead to serious problems with your heart, eyes, kidneys, nerves, gums and teeth (American Diabetes Association). Previous research has suggested proper

Diabetes is a growing concern and health challenge for the American people (b). Diabetes is a condition in which the body cannot react to insulin appropriately or either cannot produce insulin efficiently (w). “Without a properly functioning insulin signaling system, blood glucose levels become elevated and other metabolic abnormalities occur, leading to the development of serious, disabling complications” (w). There are numerous forms of diabetes amongst the nation, however, there are three main forms of diabetes. Most people have heard of type one diabetes, type two diabetes, and gestational diabetes because they are common. Type two diabetes deals with a resistance to insulin, while

Type 1 Diabetes, also called “insulin-dependent diabetes”, “juvenile diabetes”, or “early-onset diabetes”, is when the pancreas produces little to no insulin. Type 1 diabetes is not as common as type 2, but 10% of all diabetics are type 1. Patients with type 1 diabetes will need to take insulin injections for the rest of there lives. Also people with type 1

Juvenile diabetes is a version of Type 1 diabetes that occurs in children. Type I occurs because of an early degeneration of beta cells in the

Diabetes remains the 7th leading cause of death in the United States. The cost of care for diabetics and new cases of diagnosed diabetes patient’s rise more and more each year. In 2010 234’051 death certificates were issued with the mention of diabetes as a contributing factor to the death. About 60% of lower limb amputations were performed. The cost of care for diabetics is now at an astronomical high of $176 billion dollars. A change a most be made to prevent all of this loss. (American Diabetes Association, 2014)

Diabetes has become a widespread epidemic, primarily because of the increasing prevalence and incidence of type 2 diabetes. Diabetes is an endocrine disease in which the body has either a shortage of insulin or a decrease ability to use insulin or both. Insulin is a hormone that allows glucose to enter the cells and be converted into energy. Diabetes can be characterized as a prevailing, incapacitating, and deadly disease. There are a number of risk factors that increase a person’s tendency toward developing type II diabetes. Modifiable risk factors include obesity, physical inactivity and poor dietary habits are just a few. The

Diabetes continues to be a growing problem for the United States population especially type 2 diabetes, which “accounts for about 90% to 95% of all diagnosed cases of diabetes”(Center for Disease Control and Prevention (CDC), 2014). Type 2 diabetes, formally known as adult onset diabetes, is defined as a “disorder of insulin resistance in which the cells primarily within the muscle, liver, and fat tissue do not use insulin properly. As the need for insulin rises the cells in the pancreas gradually lose the ability to produce enough hormone”(CDC, 2014). Diabetes as a whole affects about “9.3% of the US population or 29.1 million people” (American Diabetes Association (ADA), 2014; CDC, 2014). Despite the high prevalence of the disease, it is only going to continue to grow if nothing is done to correct the problem. The “United States spent an estimated $245 billion on diabetes in 2012” (ADA, 2014; CDC, 2014). This outrageous number and the drastic impact diabetes has on health should emphasis the need to reduce the diabetic population in the future.

Type 1 diabetes is a disease where the pancreas no longer produces insulin for the body function properly and survive. When your body is no longer producing insulin, you will need a way to provide your body with insulin to function properly and to survive. Type 1 Diabetes in children is commonly known as juvenile diabetes or insulin-dependent diabetes.

There are 2 types of diabetes namely type 1 Diabetes Mellitus (juvenile diabetes) insulin dependent, and type 2 Diabetes Mellitus (adult – onset) insulin resistant or abnormal insulin secretion. Diabetes Mellitus type 1 is known as a genetic disease. Diabetes type 1 effect 5% of children and adolescent.

Type 1 diabetes, also referred to as Insulin Dependent Diabetes Mellitus (IDDM) or Juvenile Diabetes, can be caused by a genetic disorder. It can occur at any age, but it is most often diagnosed in children, adolescents, or young adults around 20 years old or before a person is 30 years of age. Insulin is a hormone produced by special cells, called the beta cells, in the pancreas, an organ located in the area behind the stomach. Insulin is needed to move blood sugar (glucose) into cells, where it is stored and later used for energy. In type 1 diabetes, these cells produce little or no insulin. Without enough insulin, glucose builds up in the bloodstream instead of going into the cells. The body is unable to

Diabetes is an illness that’s been raising for many years and yet there hasn’t been a cure found for it. Diabetes is diagnosed when you have too much glucose also known as sugar in your blood, where the pancreas isn’t able to make enough insulin to pass the sugar in use for energy to the different cells in your body. Glucose in the bloodstreams comes from the carbohydrate foods which are changed into sugar after we have eaten them or the glucose that’s been stored in the liver that ensures constant supply when we have not eaten recently. For a person without diabetes have a glucose level of 4 to 8 mmol/L in their body. There are three types of diabetes, type one which happens within a week or even days, unlike type two which takes as long as 10 years to be diagnosed, and gestational diabetes which happens during pregnancy. Diabetes can also lead to other health conditions, including kidney failure, eye disease, foot ulceration and a higher risk of heart disease.

Almost everyone knows somebody who is suffering from diabetes, from family members or just acquaintances; the number of people associated with diabetes is colossal. A total of 29.1 million people or 9.3% of the population have diabetes according to Centers for Disease Control and Prevention (CDC), (2014). This incredibly dreadful disease is commonly known as diabetes; its medical term is Diabetes Mellitus. “Mellitus is the Latin word for “sweet like honey”, referring to the excess glucose in the blood and urine of a patient with diabetes” according to Ladd, D. L., & Altshuler, A. (2013).

The genetics causes of Type I and Type II diabetes stem from elevated blood glucose levels. Type I diabetes is an autoimmune disease characterized by b -cell destruction, usually leading to an absolute insulin deficiency (Dahlquist 5). Type II diabetes extends from primarily insulin resistance with relative insulin deficiency to primarily defective insulin secretion with insulin resistance.

There are three different types of diabetes: type 1, type 2, and gestational diabetes. More than 13,000 youths are diagnosed with diabetes every year, making it one of the most common chronic childhood diseases in the United States (Peterson, Silverstein, Kaufman, Warren-Boulton, 2007). Type 1 diabetes, formerly known as juvenile diabetes, is “a chronic condition in which the pancreas produces little or no insulin” (Merck Manual, 2017). Type 1 diabetes results in the body’s failure to produce insulin, the hormone that unlocks the cells of the body, allowing glucose to enter and fuel them. Only 5-10% of Americans diagnosed with diabetes have Type 1. It is an autoimmune disease leading to absolute insulin deficiency resulting in